Výsledky vyhledávání - "PGC MDD Working Group"

Akademický článek

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.

Autor: Meng X; Division of Psychiatry, UCL, London, UK., Navoly G; UCL Genetics Institute, UCL, London, UK., Giannakopoulou O; Division of Psychiatry, UCL, London, UK., Levey DF; Department of Psychiatry, VA CT Healthcare Center, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Koller D; Department of Psychiatry, VA CT Healthcare Center, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Genetics, Microbiology and Statistics, University of Barcelona, Barcelona, Spain., Pathak GA; Department of Psychiatry, VA CT Healthcare Center, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Koen N; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Adams MJ; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Rentería ME; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Feng Y; Division of Psychiatry, UCL, London, UK., Gaziano JM; Department of Medicine, VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Stein DJ; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Zar HJ; SAMRC Unit on Child and Adolescent Health, Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa., Campbell ML; Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa., van Heel DA; Blizard Institute, Queen Mary University of London, London, UK., Trivedi B; Blizard Institute, Queen Mary University of London, London, UK., Finer S; Wolfson Institute of Population Health, Queen Mary University of London, London, UK., McQuillin A; Division of Psychiatry, UCL, London, UK., Bass N; Division of Psychiatry, UCL, London, UK., Chundru VK; Wellcome Sanger Institute, Saffron Walden, UK., Martin HC; Wellcome Sanger Institute, Saffron Walden, UK., Huang QQ; Wellcome Sanger Institute, Saffron Walden, UK., Valkovskaya M; Division of Psychiatry, UCL, London, UK., Chu CY; Division of Psychiatry, UCL, London, UK., Kanjira S; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Kuo PH; Department of Public Health and Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan., Chen HC; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.; Center of Sleep Disorders, National Taiwan University Hospital, Taipei, Taiwan., Tsai SJ; Institute of Brain Science and Division of Psychiatry, National Yang-Ming Chiao Tung University, Taipei, Taiwan.; Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan., Liu YL; Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli County, Taiwan., Kendler KS; Department of Psychiatry, VCU, Richmond, VA, USA., Peterson RE; Department of Psychiatry, VCU, Richmond, VA, USA.; Department of Psychiatry, SUNY Downstate Health Sciences University, Brooklyn, NY, USA., Cai N; Helmholtz Pioneer Campus, Helmholtz Munich, Neuherberg, Germany.; Computational Health Centre, Helmholtz Munich, Neuherberg, Germany.; Department of Medicine, Technical University of Munich, Munich, Germany., Fang Y; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Sen S; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA., Scott LJ; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Burmeister M; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Preuss MH; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Actkins KV; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Davis LK; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Uddin M; College of Public Health, University of South Florida, Tampa, FL, USA., Wani AH; College of Public Health, University of South Florida, Tampa, FL, USA., Wildman DE; Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA., Aiello AE; Robert N. Butler Columbia Aging Center, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Ursano RJ; Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Kessler RC; Department of Health Care Policy, Harvard Medical School, Boston, MA, USA., Kanai M; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Department of Genome Informatics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Rabinowitz JA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Maher BS; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Uhl G; Neurology and Pharmacology, University of Maryland, Maryland VA Healthcare System, Baltimore, MD, USA., Eaton W; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Cruz-Fuentes CS; Departamento de Genética, Instituto Nacional de Psiquiatría 'Ramón de la Fuente Muñíz', Mexico City, Mexico., Martinez-Levy GA; Departamento de Genética, Instituto Nacional de Psiquiatría 'Ramón de la Fuente Muñíz', Mexico City, Mexico., Campos AI; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.; Peking University Center for Public Health and Epidemic Preparedness and Response, Peking University, Beijing, China.; Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China., Wassertheil-Smoller S; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Jiang Y; Department of Biostatistics, Emory University, Atlanta, GA, USA.; 23andMe, Inc., Mountain View, CA, USA., Tian C; 23andMe, Inc., Mountain View, CA, USA., Martin NG; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Mitchell BL; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Byrne EM; Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia., Awasthi S; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Coleman JRI; Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Ripke S; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Cambridge, MA, USA., Sofer T; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.; Institute for Genomics and Cancer, University of Edinburgh, Edinburgh, UK., Polimanti R; Department of Psychiatry, VA CT Healthcare Center, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; VA Connecticut Healthcare Center, West Haven, CT, USA., Dunn EC; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Stein MB; Department of Psychiatry, UC San Diego School of Medicine, La Jolla, CA, USA.; Herbert Wertheim School of Public Health and Human Longevity, University of California San Diego, La Jolla, CA, USA.; Psychiatry Service, VA San Diego Healthcare System, San Diego, CA, USA., Gelernter J; Department of Psychiatry, VA CT Healthcare Center, West Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA., Lewis CM; Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Department of Medical and Molecular Genetics, King's College London, London, UK., Kuchenbaecker K; Division of Psychiatry, UCL, London, UK. k.kuchenbaecker@ucl.ac.uk.; UCL Genetics Institute, UCL, London, UK. k.kuchenbaecker@ucl.ac.uk.

Publikováno v: Nature genetics [Nat Genet] 2024 Feb; Vol. 56 (2), pp. 222-233. Date of Electronic Publication: 2024 Jan 04.