Výsledky vyhledávání - "PG, peptidoglycan"

Lytic transglycosylase MltG cleaves in nascent peptidoglycan and produces short glycan strands

Autor: Sassine, Jad, Pazos, Manuel, Breukink, Eefjan, Vollmer, Waldemar, Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics

Publikováno v: The Cell Surface, Vol 7, Iss, Pp 100053-(2021)
The Cell Surface
The Cell Surface, 7, 1. Elsevier BV

Bacteria encase their cytoplasmic membrane with peptidoglycan (PG) to maintain the shape of the cell and protect it from bursting. The enlargement of the PG layer is facilitated by the coordinated activities of PG synthesising and -cleaving enzymes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb7d63fa41b501d9bd50798fe7b7a4c
http://www.sciencedirect.com/science/article/pii/S2468233021000062

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Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria

Autor: Sarah G. Whaley, Matthew W. Frank, Christopher D. Radka, Charles O. Rock, Chitra Subramanian

Publikováno v: The Journal of Biological Chemistry

Bacterial fatty acid synthesis in Escherichia coli is initiated by the condensation of an acetyl-CoA with a malonyl-acyl carrier protein (ACP) by the β-ketoacyl-ACP synthase III enzyme, FabH. E. coli ΔfabH knockout strains are viable because of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403bca77b66efe2dad00899b24173d60
https://pubmed.ncbi.nlm.nih.gov/34801557

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Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni

Autor: Martin E. Tanner, Jacob A. Brockerman, Chang Sheng-Huei Lin, Jean-Pierre Simorre, Erin C. Gaynor, Jenny Vermeulen, Lawrence P. McIntosh, Anson C. K. Chan, Arvind Soni, Michael E. P. Murphy

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 296, pp.100528. ⟨10.1016/j.jbc.2021.100528⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 296, pp.100528. ⟨10.1016/j.jbc.2021.100528⟩
The Journal of Biological Chemistry

International audience; The helical morphology of Campylobacter jejuni, a bacterium involved in host gut colonization and pathogenesis in humans, is determined by the structure of the peptidoglycan (PG) layer. This structure is dictated by trimming o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0e0e23388d36bc0f74269c64db3c73
https://hal.science/hal-03328690

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Synthetic mimetics of the endogenous gastrointestinal nanomineral: Silent constructs that trap macromolecules for intracellular delivery

Autor: Jack Robertson, Laetitia C. Pele, Juan C. Hernández-Garrido, Rachel E. Hewitt, Nuno Jorge Rodrigues Faria, Helen F. Chappell, Andy Brown, Jeremy N. Skepper, Jonathan J. Powell, Paul A. Midgley, Carolin T Haas

Publikováno v: Nanomedicine

Amorphous magnesium-substituted calcium phosphate (AMCP) nanoparticles (75-150 nm) form constitutively in large numbers in the mammalian gut. Collective evidence indicates that they trap and deliver luminal macromolecules to mucosal antigen presentin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bd3e00b9f852e7ed40f2e8791990be
https://doi.org/10.1016/j.nano.2016.07.008

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ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis

Autor: J. Harry Caufield, Norman Goodacre, Tanneke den Blaauwen, Alla Gagarinova, Sergey M. Vorobiev, Randy M. Morgenstein, Peter Uetz, Gaetano T. Montelione, Jitender Mehla, Mary Brockett, John F. Hunt, Mohan Babu, Rong Xiao, Neha Sakhawalkar, Sadhna Phanse, Ali Hosseinnia, George W. Liechti

Publikováno v: The Journal of Biological Chemistry

YhcB, a poorly understood protein conserved across gamma-proteobacteria, contains a domain of unknown function (DUF1043) and an N-terminal transmembrane domain. Here, we used an integrated approach including X-ray crystallography, genetics, and molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04d0bee8d94d22030f83b723978e99d
https://doi.org/10.1016/j.jbc.2021.100700

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Conjugative type IV secretion systems in Gram-positive bacteria

Autor: Nikolaus Goessweiner-Mohr, Elisabeth Grohmann, Karsten Arends, Walter Keller

Publikováno v: Plasmid

Highlights • The conjugative transfer mechanism of broad-host-range, Enterococcus sex pheromone and Clostridium plasmids is reviewed. • Comparisons with Gram-negative type IV secretion systems are presented. • The current understanding of the u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90315ffe35f7ceff0dc77fb50f9706f
https://doi.org/10.1016/j.plasmid.2013.09.005

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Akademický článek

Recent developments on UDP-N-acetylmuramoyl-L-alanine-D-gutamate ligase (Mur D) enzyme for antimicrobial drug development: An emphasis on in-silico approaches.

Autor: Gaur V; Department of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Punjab, 144411, India., Bera S; Department of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Punjab, 144411, India.

Publikováno v: Current research in pharmacology and drug discovery [Curr Res Pharmacol Drug Discov] 2022 Nov 03; Vol. 3, pp. 100137. Date of Electronic Publication: 2022 Nov 03 (Print Publication: 2022).

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Akademický článek

Towards discovery of inhibitors of the undecaprenyl-pyrophosphate phosphatase BacA by virtual high-throughput screening.

Autor: Jukič M; University of Maribor, Faculty of Chemistry and Chemical Engineering, Laboratory of Physical Chemistry and Chemical Thermodynamics, Smetanova 17, Maribor SI-2000, Slovenia.; University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Glagoljaška 8, Koper SI-6000, Slovenia., Auger R; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette FR-91198, France., Folcher V; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette FR-91198, France., Proj M; Univerza v Ljubljani, Fakulteta za Farmacijo, Aškerčeva cesta 7, Ljubljana SI-1000, Slovenia., Barreteau H; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette FR-91198, France., Gobec S; Univerza v Ljubljani, Fakulteta za Farmacijo, Aškerčeva cesta 7, Ljubljana SI-1000, Slovenia., Touzé T; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette FR-91198, France.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2022 May 11; Vol. 20, pp. 2360-2371. Date of Electronic Publication: 2022 May 11 (Print Publication: 2022).

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Akademický článek

Antimicrobial peptide gene induction, involvement of Toll and IMD pathways and defense against bacteria in the red flour beetle, Tribolium castaneum.

Autor: Yokoi K; Applied Entomology Laboratory, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan., Koyama H; Applied Entomology Laboratory, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan., Minakuchi C; Applied Entomology Laboratory, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan., Tanaka T; Applied Entomology Laboratory, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan., Miura K; Applied Entomology Laboratory, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan.

Publikováno v: Results in immunology [Results Immunol] 2012 Mar 30; Vol. 2, pp. 72-82. Date of Electronic Publication: 2012 Mar 30 (Print Publication: 2012).

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