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Understanding PFAS toxicity through cell culture metabolomics: Current applications and future perspectives

Autor: Nguyen, Thao V., Trang, Phan Nguyen, Kumar, Anu

Publikováno v: In Environment International April 2024 186

Understanding PFAS toxicity through cell culture metabolomics: Current applications and future perspectives

Autor: Thao V. Nguyen, Phan Nguyen Trang, Anu Kumar

Publikováno v: Environment International, Vol 186, Iss , Pp 108620- (2024)

Per- and polyfluoroalkyl substances (PFAS), ubiquitous environmental contaminants, pose significant challenges to ecosystems and human health. While cell cultures have emerged as new approach methodologies (NAMs) in ecotoxicity research, metabolomics

Externí odkaz: https://doaj.org/article/03040ff690ed4bfc85b9ec53dbbf178a

Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity

Autor: Stefano Palazzolo, Isabella Caligiuri, Andrea Augusto Sfriso, Matteo Mauceri, Rossella Rotondo, Davide Campagnol, Vincenzo Canzonieri, Flavio Rizzolio

Publikováno v: Toxics, Vol 10, Iss 2, p 91 (2022)

Short-chain per-fluoroalkyl substances (PFAS) have replaced long-chains in many applications, however the toxicity and its mode of action and interactions due to the large number of these compounds and their mixtures is still poorly understood. The p

Externí odkaz: https://doaj.org/article/6d0442579bfc4ed4b44eb395956845fe

Diet as an Exposure Source and Mediator of Per- and Polyfluoroalkyl Substance (PFAS) Toxicity.

Autor: Roth K; Institute of Environmental Health Sciences, Wayne State University, Detroit, MI, United States., Imran Z; Department of Chemistry, Wayne State University, Detroit, MI, United States., Liu W; Department of Pharmaceutical Sciences, College of Pharmacy, Wayne State University, Detroit, MI, United States.; Department of Pharmacology, School of Medicine, Wayne State University, Detroit, MI, United States., Petriello MC; Institute of Environmental Health Sciences, Wayne State University, Detroit, MI, United States.; Department of Pharmacology, School of Medicine, Wayne State University, Detroit, MI, United States.

Publikováno v: Frontiers in toxicology [Front Toxicol] 2020 Dec 04; Vol. 2, pp. 601149. Date of Electronic Publication: 2020 Dec 04 (Print Publication: 2020).