Zobrazeno 1 - 10
of 10 807
pro vyhledávání: '"PET-imaging"'
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background Type 1 diabetes (T1D) is an autoimmune disease characterized by a progressive β-cell destruction. There are no clinically established methods for quantifying endocrine cells of the pancreas and current knowledge is almost exclusi
Externí odkaz:
https://doaj.org/article/3edfc8c9823444cf8097dcc5e1ddafd2
Autor:
Pan Zhou, Kai Ning, Shuai Xue, Qingqing Li, Danni Li, Haijun Yang, Zeying Liang, Rou Li, Jian Yang, Xiao Li, Lan Zhang
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Background Angiotensin-converting enzyme-2 (ACE2) acts as a key regulatory molecule and important therapeutic target in the pathological remodeling of numerous organs and diseases. In this study, a rapid, simple, and efficient synthetic rout
Externí odkaz:
https://doaj.org/article/468e2eb0332941ad8b5f9c7f213eecf9
Autor:
Francesco Lechi, Jonas Eriksson, Luke R. Odell, Olivia Wegrzyniak, John Löfblom, Fredrik Y. Frejd, Bo Zhang, Olof Eriksson
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Background In recent years, the interest in Al[18F]F as a labeling agent for Positron Emission Tomography (PET) radiotracers has risen, as it allows for fast and efficient fluorine-18 labeling by harnessing chelation chemistry. The introduct
Externí odkaz:
https://doaj.org/article/1e47d67acbb5417c88a66699c63b9e28
Autor:
Kiwon Kim, Yoo Jin Jang, Jeong-Hyeon Shin, Mi Jin Park, Hyun Soo Kim, Joon-Kyung Seong, Hong Jin Jeon
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Although depression is linked to an increased risk of dementia, the association between late-onset depression (LOD) and amyloid burden remains unclear. This study aimed to determine amyloid deposition in patients with LOD compared
Externí odkaz:
https://doaj.org/article/e129760857f4458c822d73ca56a937d0
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Hepatocellular cancer (HCC) remained a life-threatening carcinoma. Agents for HCC imaging and therapy were expected to possess different intratumoral retention time. To construct an agent with different intratumoral retention time when appli
Externí odkaz:
https://doaj.org/article/bdc2f6f6f3b1461297876c14ec76c095
Autor:
Anika Wuestefeld, Alexa Pichet Binette, Danielle van Westen, Olof Strandberg, Erik Stomrud, Niklas Mattsson-Carlgren, Shorena Janelidze, Ruben Smith, Sebastian Palmqvist, Hannah Baumeister, David Berron, Paul A. Yushkevich, Oskar Hansson, Nicola Spotorno, Laura E.M. Wisse
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background The medial temporal lobe (MTL) is hypothesized to be relatively spared in early-onset Alzheimer’s disease (EOAD). Yet, detailed examination of MTL subfields and drivers of atrophy in amnestic EOAD is lacking. Methods BioFINDER-2
Externí odkaz:
https://doaj.org/article/b9abd4ab96174d0c88ed8964d092f79e
Autor:
Junqi Hu, Yinlong Li, Chenchen Dong, Huiyi Wei, Kai Liao, Junjie Wei, Chunyu Zhao, Ahmad Chaudhary, Jiahui Chen, Hao Xu, Ke Zhong, Steven H. Liang, Lu Wang, Weijian Ye
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4014-4027 (2024)
The arginine-vasopressin (AVP) hormone plays a pivotal role in regulating various physiological processes, such as hormone secretion, cardiovascular modulation, and social behavior. Recent studies have highlighted the V1a receptor as a promising ther
Externí odkaz:
https://doaj.org/article/3d89230ad29d4937a8d0aff7aaaff0fb
Autor:
Louis Lauwerys, Lucas Beroske, Angelo Solania, Christel Vangestel, Alan Miranda, Nele Van Giel, Karuna Adhikari, Anne-Marie Lambeir, Leonie wyffels, Dennis Wolan, Pieter Van der Veken, Filipe Elvas
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-26 (2024)
Abstract Background The cysteine-aspartic acid protease caspase-3 is recognized as the main executioner of apoptosis in cells responding to specific extrinsic and intrinsic stimuli. Caspase-3 represents an interesting biomarker to evaluate treatment
Externí odkaz:
https://doaj.org/article/7d195dcb92624a9bab00b7cbe35e7adc
Autor:
Ling Wang, Xue Zhu, Yan Xue, Zhihong Huang, Wenjun Zou, Zhengwei Zhang, Mengxi Yu, Donghui Pan, Ke Wang
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background Uveal melanoma (UM) is the most common primary intraocular tumor in adults, and early detection is critical to improve the clinical outcome of this disease. In this study, the diagnostic effectiveness of [18F]AlF-NOTA-PRGD2 (an in
Externí odkaz:
https://doaj.org/article/e963af5c09434217913f0745c5ffea7d
Autor:
Qian Zhang, Haizhen Du, Xiuli Ma, Song Liu, Xiangxing Kong, Muye Hu, Jing Shi, Yanfang Tang, ShuHui Liu, Xun Meng, Qian Guo, Yan Kong, Jun Guo, Bin Lian, Zhi Yang, Hua Zhu
Publikováno v:
View, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract In the context of precision diagnosis for various subtypes of melanoma, identifying biomarkers with clinical translational potential from a molecular standpoint is crucial for a more comprehensive characterization of the disease. Mucin 18 (M
Externí odkaz:
https://doaj.org/article/e77badb4bfd9401ba3bb7dd9447bd0d4