Zobrazeno 1 - 10
of 115
pro vyhledávání: '"PENGYUAN ZHENG"'
Autor:
Simeng Liu, Huayuan Xi, Xia Xue, Xiangdong Sun, Huang Huang, Dongjun Fu, Yang Mi, Yongzheng He, Pingchang Yang, Youcai Tang, Pengyuan Zheng
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder that has been found to be associated with dysregulation of gastrointestinal functions and gut microbial homeostasis (the so-called “gut-brain axis”). ASD
Externí odkaz:
https://doaj.org/article/dae1c8c833dd4120940f46c2cd30bf5f
Autor:
Simeng Liu, Huijuan Wen, Fazhan Li, Xia Xue, Xiangdong Sun, Fuhao Li, Ruoyu Hu, Huayuan Xi, Francesco Boccellato, Thomas F Meyer, Yang Mi, Pengyuan Zheng
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Gastric intestinal metaplasia (GIM) is an essential precancerous lesion. Although the reversal of GIM is challenging, it potentially brings a state-to-art strategy for gastric cancer therapeutics (GC). The lack of the appropriate
Externí odkaz:
https://doaj.org/article/9ce16ff024ee41068d4718c07694e629
Autor:
Xuecui Yin, Lin Dong, Xiaohan Wang, Zhenzhen Qin, Yuying Ma, Xiaofei Ke, Ya Li, Qingde Wang, Yang Mi, Quanjun Lyu, Xia Xu, Pengyuan Zheng, Youcai Tang
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 2, Pp 166-178 (2024)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases globally. Hepatic stellate cells (HSCs) are the major effector cells of liver fibrosis. HSCs contain abundant lipid droplets (LDs) in their
Externí odkaz:
https://doaj.org/article/819eb71873144d5eade6111c079560ce
Autor:
Ruoyu Hu, Xia Xue, Xiangdong Sun, Yang Mi, Huijuan Wen, Huayuan Xi, Fuhao Li, Pengyuan Zheng, Simeng Liu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveGastric intestinal metaplasia (IM) is a precancerous stage associated with gastric cancer. Despite the observed beneficial effects of metformin on IM, its molecular mechanism remains not fully elucidated. This study aims to reveal the effect
Externí odkaz:
https://doaj.org/article/1cd4b2e68c49438bbf9e6f22dab84334
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33637- (2024)
Background: Revealing the role of anoikis resistance plays in CRC is significant for CRC diagnosis and treatment. This study integrated the CRC anoikis-related key genes (CRC-AKGs) and established a novel model for improving the efficiency and accura
Externí odkaz:
https://doaj.org/article/67335e36dc2543e8922e0c652acd5e70
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31621- (2024)
Activated hepatic stellate cells (HSCs) have been widely recognized as a primary source of pathological myofibroblasts, leading to the accumulation of extracellular matrix and liver fibrosis. CD47, a transmembrane glycoprotein expressed on the surfac
Externí odkaz:
https://doaj.org/article/e1fa13ad33f0405eb0eaeb5b0b2e840a
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Objective: Vitamin D3 has the general properties of a lipid-soluble vitamin, but is also an active steroid hormone that can regulate the proliferation, apoptosis and differentiation of many tumor cells, and exerts anticancer activity against numerous
Externí odkaz:
https://doaj.org/article/464859a4da374c9ba3e89a6c249d1a66
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The development of cancer is not just the growth and proliferation of a single transformed cell, but its tumor microenvironment (TME) also coevolves with it, which is primarily involved in tumor initiation, development, metastasis, and therapeutic re
Externí odkaz:
https://doaj.org/article/4f65e1b867c840808d03a3195d7e3ad8
Autor:
Qian Li, Man Wang, Yue Zhang, Yubing Li, Xianfen Zhang, Haowei Li, Ying Peng, Changlian Zhu, Pengyuan Zheng, Shaolong Yang, Jiang Li, Jiafu Lin, Rong He, Hongmei Zhang, Huoxiang Zhou
Publikováno v:
Journal of Functional Foods, Vol 112, Iss , Pp 105928- (2024)
Pectic oligosaccharides have been proposed as a novel prebiotic to prevent obesity and associated with metabolic disorders by regulating gut microbiota, but their various probiotic functions in the gut depended on their complex and heterogeneous suga
Externí odkaz:
https://doaj.org/article/4c278e10947e4095bb7f3ab7c4cd984b
Autor:
Qiang Zhang, Chunjing Qiu, Wenya Jiang, Pengya Feng, Xia Xue, Ihtisham Bukhari, Yang Mi, Pengyuan Zheng
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22677- (2023)
Dioctyl phthalate, commonly known as bis(2-ethylhexyl) phthalate (DEHP), is a widely used plasticizer in various industries and has been shown to directly or indirectly impact human health. However, there is a lack of comprehensive studies evaluating
Externí odkaz:
https://doaj.org/article/8723e59b91b249be9ab8c7f4af75d4f3