Zobrazeno 1 - 10
of 878
pro vyhledávání: '"PENG-SHENG CHEN"'
Autor:
Neal Yuan, Nathan R. Stein, Grant Duffy, Roopinder K. Sandhu, Sumeet S. Chugh, Peng-Sheng Chen, Carine Rosenberg, Christine M. Albert, Susan Cheng, Robert J. Siegel, David Ouyang
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Atrial fibrillation (AF) often escapes detection, given its frequent paroxysmal and asymptomatic presentation. Deep learning of transthoracic echocardiograms (TTEs), which have structural information, could help identify occult AF. We create
Externí odkaz:
https://doaj.org/article/deecdc10d70844219eb04a44f0a65baf
Autor:
Joseph E. Ebinger, Matthew P. Driver, Tzu Yu Huang, Jose Magraner, Patrick G. Botting, Minhao Wang, Peng-Sheng Chen, Natalie A. Bello, David Ouyang, John Theurer, Susan Cheng, Zaldy S. Tan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Blood pressure variability (BPV) and heart rate variability (HRV) have been associated with Alzheimer’s Disease and Related Dementias (ADRD) in rigorously controlled studies. However, the extent to which BPV and HRV may offer predictive in
Externí odkaz:
https://doaj.org/article/a8386b2b6000465688060eb77583806c
Publikováno v:
Tzu-Chi Medical Journal, Vol 33, Iss 4, Pp 339-344 (2021)
Calmodulin (CaM) is a ubiquitous intracellular calcium sensor that controls and regulates key cellular functions. In all vertebrates, three CaM genes located on separate chromosomes encode an identical 149 amino acid protein, implying an extraordinar
Externí odkaz:
https://doaj.org/article/00267fa257534997a12c4ccd3bd5ebd2
Autor:
Songwen Chen, Guannan Meng, Anisiia Doytchinova, Johnson Wong, Susan Straka, Julie Lacy, Xiaochun Li, Peng-Sheng Chen, Thomas H. Everett IV
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Skin sympathetic nerve activity (SKNA) and QT interval variability are known to be associated with ventricular arrhythmias. However, the relationship between the two remains unclear.Objective: The aim was to test the hypothesis that SKNA
Externí odkaz:
https://doaj.org/article/02a2c60700f541e7ab9bcd6b01f1ab0b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Small-conductance Ca2+-activated K+ channels (SK channels) have been proposed as antiarrhythmic targets for the treatment of atrial fibrillation. We previously demonstrated that the 5-HT3 receptor antagonist ondansetron inhibits heterolog
Externí odkaz:
https://doaj.org/article/a4e47335c57740cabe3b2d96dcf36359
Autor:
Hugh Calkins, MD, Gerhard Hindricks, MD, Riccardo Cappato, MD, Young-Hoon Kim, MD, PhD, Eduardo B. Saad, MD, PhD, Luis Aguinaga, MD, PhD, Joseph G. Akar, MD, PhD, Vinay Badhwar, MD, Josep Brugada, MD, PhD, John Camm, MD, Peng-Sheng Chen, MD, Shih-Ann Chen, MD, Mina K. Chung, MD, Jens Cosedis Nielsen, DMSc, PhD, Anne B. Curtis, MD, D. Wyn Davies, MD, John D. Day, MD, André d’Avila, MD, PhD, N.M.S. (Natasja) de Groot, MD, PhD, Luigi Di Biase, MD, PhD, Mattias Duytschaever, MD, PhD, James R. Edgerton, MD, Kenneth A. Ellenbogen, MD, Patrick T. Ellinor, MD, PhD, Sabine Ernst, MD, PhD, Guilherme Fenelon, MD, PhD, Edward P. Gerstenfeld, MS, MD, David E. Haines, MD, Michel Haissaguerre, MD, Robert H. Helm, MD, Elaine Hylek, MD, MPH, Warren M. Jackman, MD, Jose Jalife, MD, Jonathan M. Kalman, MBBS, PhD, Josef Kautzner, MD, PhD, Hans Kottkamp, MD, Karl Heinz Kuck, MD, PhD, Koichiro Kumagai, MD, PhD, Richard Lee, MD, MBA, Thorsten Lewalter, MD, PhD, Bruce D. Lindsay, MD, Laurent Macle, MD, Moussa Mansour, MD, Francis E. Marchlinski, MD, Gregory F. Michaud, MD, Hiroshi Nakagawa, MD, PhD, Andrea Natale, MD, Stanley Nattel, MD, Ken Okumura, MD, PhD, Douglas Packer, MD, Evgeny Pokushalov, MD, PhD, Matthew R. Reynolds, MD, MSc, Prashanthan Sanders, MBBS, PhD, Mauricio Scanavacca, MD, PhD, Richard Schilling, MD, Claudio Tondo, MD, PhD, Hsuan-Ming Tsao, MD, Atul Verma, MD, David J. Wilber, MD, Teiichi Yamane, MD, PhD
Publikováno v:
Journal of Arrhythmia, Vol 33, Iss 5, Pp 369-409 (2017)
Externí odkaz:
https://doaj.org/article/dbe4ae4338c346e09a7f0ad99807e40d
Autor:
Jin Yang, Konstantinos Savvatis, Jong Seok Kang, Peidong Fan, Hongyan Zhong, Karen Schwartz, Vivian Barry, Amanda Mikels-Vigdal, Serge Karpinski, Dmytro Kornyeyev, Joanne Adamkewicz, Xuhui Feng, Qiong Zhou, Ching Shang, Praveen Kumar, Dillon Phan, Mario Kasner, Begoña López, Javier Diez, Keith C. Wright, Roxanne L. Kovacs, Peng-Sheng Chen, Thomas Quertermous, Victoria Smith, Lina Yao, Carsten Tschöpe, Ching-Pin Chang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Lysyl oxidase-like 2 (LOXL2) is an enzyme that promotes scaffolding of extracellular matrix proteins. Here the authors show that LOXL2 is crucial for pressure-overload induced cardiac fibrosis, and that antibody-mediated inhibition or genetic disrupt
Externí odkaz:
https://doaj.org/article/3c49e4174d5d4829a56a0c196d697c78
Autor:
Michael A. Olaopa, Katherine G. Spoonamore, Deepak Bhakta, Zhenhui Chen, Patricia B.S. Celestino-Soper, Peng-Sheng Chen, Tomohiko Ai, Matteo Vatta
Publikováno v:
Cardiogenetics, Vol 8, Iss 1 (2018)
Variants in the LMNA gene, which encodes Lamin-A/C, have been commonly associated with cardiac conduction system diseases usually accompanying cardiomyopathy. We have seen two unrelated patients who presented with atrioventricular block (AVB) with or
Externí odkaz:
https://doaj.org/article/a6cb82b6b1e1409285d13902c23e6978
Autor:
Thomas A. Reher, Zhuo Wang, Chia‐Hsiang Hsueh, Po‐Cheng Chang, Zhenwei Pan, Mohineesh Kumar, Jheel Patel, Jian Tan, Changyu Shen, Zhenhui Chen, Michael C. Fishbein, Michael Rubart, Penelope Boyden, Peng‐Sheng Chen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)
BackgroundPurkinje cells (PCs) are important in cardiac arrhythmogenesis. Whether small‐conductance calcium‐activated potassium (SK) channels are present in PCs remains unclear. We tested the hypotheses that subtype 2 SK (SK2) channel proteins an
Externí odkaz:
https://doaj.org/article/0dd4e074bcce432c9c5a81e2b05a81cb
Autor:
Tecla M Temu, Kathleen A Lane, Changyu Shen, Loise Ng'ang'a, Constantine O Akwanalo, Peng-Sheng Chen, Wilfred Emonyi, Susan R Heckbert, Myra M Koech, Imran Manji, Matteo Vatta, Eric J Velazquez, Jennifer Wessel, Sylvester Kimaiyo, Thomas S Inui, Gerald S Bloomfield
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185204 (2017)
Atrial fibrillation (AF) is a major contributor to the global cardiovascular disease burden. The clinical profile and outcomes of AF patients with valvular heart diseases in sub-Saharan Africa (SSA) have not been adequately described. We assessed cli
Externí odkaz:
https://doaj.org/article/c79e0682a14646eda5e992f5bd475375