Zobrazeno 1 - 10
of 37
pro vyhledávání: '"PEAQX"'
Autor:
Lind, Genevieve E., Mou, Tung-Chung, Tamborini, Lucia, Pomper, Martin G., De Micheli, Carlo, Conti, Paola, Pinto, Andrea, Hansen, Kasper B.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Aug . 114(33), E6942-E6951.
Externí odkaz:
https://www.jstor.org/stable/26487087
Autor:
Mitsuhiko Yamada, Hiroki Furuie
Publikováno v:
Neuroscience Research. 176:57-65
The immature brain is highly sensitive to disturbances in the functioning of N-methyl- d -aspartate (NMDA) receptor in rodents, and blockade of the receptor during postnatal brain development period causes schizophrenia-like behavior in adulthood. Du
Autor:
Hong-Li Chi, Tong Xiao, Xiao-Jing Yu, Hong-Li Gao, Abdoulaye Issotina Zibrila, Yu-Ming Kang, Hong-Bao Li, Ying Li, Jie Qi, Yan Zhang, Xiao-Lian Shi, Li-Yan Fu, Yu-Xin Lu, Qing Su, Yan-Mei Chen
Publikováno v:
American Journal of Hypertension. 34:840-850
BACKGROUND N-Methyl-d-aspartate receptor (NMDAR) in the hypothalamic paraventricular nucleus (PVN) plays critical roles in regulating sympathetic outflow. Studies showed that acute application of the antagonists of NMDAR or its subunits would reduce
Publikováno v:
Neuropharmacology. 148:11-20
24S-hydroxycholesterol (24HC) is the major metabolic breakdown product of cholesterol in the brain. Among its other effects on neurons, 24HC modulates N-methyl-D-aspartate (NMDA or GluN) receptors, but our understanding of this mechanism is poor. We
Autor:
Chun-Ping Chu, Guang-Jian Zhang, Bai-Ri Cui, Yan-Hua Bing, Xin-Yuan Zhang, Bing-Xue Li, Li-Na Cui, De-Lai Qiu
Publikováno v:
Neuroscience letters. 736
N-methyl-D-aspartate receptors (NMDARs) are expressed in granule cell and involve in mossy fiber-granule cell (MF-GC) synaptic transmission in cerebellar cortex. In the absence GABAA receptor activity, we here studied the role of NMDARs during the fa
Publikováno v:
Physiology & Behavior. 177:44-48
N-methyl-d-aspartate (NMDA) receptors are crucial synaptic elements in long-term memory formation, including the associative learning of fearful events. Although NMDA blockers were consistently shown to inhibit fear memory acquisition and recall, the
Publikováno v:
Journal of the Neurological Sciences. 376:166-175
Sigma-1 receptor (σ1r) activation could attenuate the learning and memory deficits in the AD model, ischemia model and others. In our previous study, the activation of σ1r increased the expression of brain-derived neurotrophic factor (BDNF), possib
Autor:
Fernando Osuna-Lopez, Irving S Aguilar-Martinez, Eloy G. Moreno-Galindo, Raúl Aguilar-Roblero, Luis Castro-Sánchez, Javier Alamilla, Ricardo A. Navarro-Polanco, Herrera-Zamora Jm, Miriam E. Reyes-Mendez, Enrique Sánchez-Pastor
Publikováno v:
Journal of biological rhythms. 34(1)
The suprachiasmatic nucleus (SCN) is the main brain clock that regulates circadian rhythms in mammals. The SCN synchronizes to the LD cycle through the retinohypothalamic tract (RHT), which projects to ventral SCN neurons via glutamatergic synapses.
Autor:
Maria F. M. Braga, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, Vassiliki Aroniadou-Anderjaska
Publikováno v:
Neuroscience. 373
Synchronous, rhythmic firing of GABAergic interneurons is a fundamental mechanism underlying the generation of brain oscillations, and evidence suggests that NMDA receptors (NMDARs) play a key role in oscillatory activity by regulating the activity o
Autor:
Andrea Pinto, Carlo De Micheli, Genevieve E. Lind, Martin G. Pomper, Tung-Chung Mou, Lucia Tamborini, Kasper B. Hansen, Paola Conti
Publikováno v:
Proceedings of the National Academy of Sciences. 114
NMDA-type glutamate receptors are ligand-gated ion channels that contribute to excitatory neurotransmission in the central nervous system (CNS). Most NMDA receptors comprise two glycine-binding GluN1 and two glutamate-binding GluN2 subunits (GluN2A-D