Výsledky vyhledávání - "PE24 exotoxin"

Akademický článek

GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases

Autor: Rita Sala, Elisa Rioja-Blanco, Naroa Serna, Laura Sánchez-García, Patricia Álamo, Lorena Alba-Castellón, Isolda Casanova, Antonio López-Pousa, Ugutz Unzueta, María Virtudes Céspedes, Esther Vázquez, Antonio Villaverde, Ramon Mangues

Publikováno v: Drug Delivery, Vol 29, Iss 1, Pp 1384-1397 (2022)

Colorectal cancer (CRC) remains the third cause of cancer-related mortality in Western countries, metastases are the main cause of death. CRC treatment remains limited by systemic toxicity and chemotherapy resistance. Therefore, nanoparticle-mediated

Externí odkaz: https://doaj.org/article/cd8cbc74b6b642dead764be19bd723bb

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Selective delivery of T22-PE24-H6 to CXCR4 + diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model

Autor: Falgàs, Aïda, Pallarès, Victor, Serna, Naroa, Sánchez García, Laura, Sierra, Jorge, Gallardo, Alberto, Alba-Castellón, Lorena, Álamo, Patricia, Unzueta Elorza, Ugutz, Villaverde Corrales, Antonio, Vázquez Gómez, Esther, Mangues, Ramon, Casanova Rigat, Isolda, Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

Altres ajuts: EU COST Action CA 17140 to R.M., FIS PI17/01246 and RD16/0011/0028 to J.S., and FIS PI15/00272 to E.V. CIBER-BBN [CB06/01/1031 and 4NanoMets to R.M., and VENOM4CANCER to A.V.]. a grant from the Generalitat de Catalunya (PERIS) [SLT002/1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8019737c0961b1e9865a8bd77dcc0a
https://ddd.uab.cat/record/227754

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Selective delivery of T22-PE24-H6 to CXCR4(+) diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model

Autor: Falgàs, Aïda, Pallarès, Victor, Serna, Naroa, Sánchez, Laura, Sierra, Jorge, Gallardo, Alberto, Alba-Castellón, Lorena, Álamo, Patricia, Unzueta Elorza, Ugutz, Villaverde Corrales, Antonio, Vázquez Gómez, Esther, Mangues, Ramon, Casanova Rigat, Isolda

Publikováno v: Theranostics
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Background: Novel therapeutic strategies are urgently needed to reduce relapse rates and enhance survival in Diffuse Large B-Cell Lymphoma (DLBCL) patients. CXCR4-overexpressing cancer cells are good targets for therapy because of their association w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c04e58d3bdfa0f35216d0000557b29a4
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2145

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Selective delivery of T22-PE24-H6 to CXCR4

Autor: Aïda, Falgàs, Victor, Pallarès, Naroa, Serna, Laura, Sánchez-García, Jorge, Sierra, Alberto, Gallardo, Lorena, Alba-Castellón, Patricia, Álamo, Ugutz, Unzueta, Antonio, Villaverde, Esther, Vázquez, Ramon, Mangues, Isolda, Casanova

Publikováno v: Theranostics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df35f9757188b64c8bf0e8805d25af58
https://pubmed.ncbi.nlm.nih.gov/32373205

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Akademický článek

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Akademický článek

Selective delivery of T22-PE24-H6 to CXCR4 ⁺ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model.

Autor: Falgàs A; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Pallarès V; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Serna N; Institute of Biotechnology and Biomedicine (IBB), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, Spain., Sánchez-García L; Institute of Biotechnology and Biomedicine (IBB), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, Spain., Sierra J; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, Spain.; Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Gallardo A; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain., Alba-Castellón L; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain., Álamo P; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Unzueta U; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Villaverde A; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain.; Institute of Biotechnology and Biomedicine (IBB), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, Spain., Vázquez E; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain.; Institute of Biotechnology and Biomedicine (IBB), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, Spain., Mangues R; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain., Casanova I; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona Spain.; Josep Carreras Leukaemia Research Institute (IJC), Barcelona, Spain.; CIBER de Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain.

Publikováno v: Theranostics [Theranostics] 2020 Apr 06; Vol. 10 (12), pp. 5169-5180. Date of Electronic Publication: 2020 Apr 06 (Print Publication: 2020).

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