Real-world biologics response and super-response in the International Severe Asthma Registry cohort.

Autor: Denton E; Allergy, Asthma & Clinical Immunology, Alfred Health, Melbourne, Victoria, Australia.; Department of Medicine, Central Clinical School, Monash University, Melbourne, Victoria, Australia., Hew M; Allergy, Asthma & Clinical Immunology, Alfred Health, Melbourne, Victoria, Australia.; Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Peters MJ; Department of Thoracic Medicine, Concord Hospital, Sydney, New South Wales, Australia.; Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia., Upham JW; Frazer Institute & PA-Southside Clinical Unit, The University of Queensland, Brisbane, Queensland, Australia., Bulathsinhala L; Optimum Patient Care Global, Cambridge, UK.; Observational and Pragmatic Research Institute, Singapore, Singapore., Tran TN; BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Maryland, USA., Martin N; BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Maryland, USA.; Department of Respiratory Medicine, University of Leicester, Leicester, UK., Bergeron C; Centre for Lung Health, Vancouver General Hospital, Vancouver, British Columbia, Canada.; University of British Columbia, Vancouver, British Columbia, Canada., Al-Ahmad M; Microbiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait.; Al-Rashed Allergy Center, Ministry of Health, Kuwait City, Kuwait., Altraja A; Department of Pulmonology, University of Tartu and Lung Clinic, Tartu University Hospital, Tartu, Estonia., Larenas-Linnemann D; Centro de Excelencia en Asma y Alergia, Hospital Médica Sur, Mexico City, Mexico., Murray R; Optimum Patient Care Global, Cambridge, UK., Celis-Preciado CA; Pulmonary Unit, Hospital Universitario San Ignacio, Bogota, Colombia.; Faculty of Medicine, Pontificia Universidad Javeriana, Bogota, Colombia., Al-Lehebi R; Department of Pulmonology, King Fahad Medical City, Riyadh, Saudi Arabia.; Alfaisal University, Riyadh, Saudi Arabia., Belhassen M; PELyon, Lyon, France., Bhutani M; Department of Medicine, Division of Pulmonary Medicine, University of Alberta, Alberta, Canada., Bosnic-Anticevich SZ; Faculty of Medicine, Health and Human Sciences, Macquarie Medical School, Macquarie University, Sydney, New South Wales, Australia.; Woolcock Institute of Medical Research, Sydney, New South Wales, Australia., Bourdin A; PhyMedExp, University of Montpellier, CNRS, INSERM, CHU Montpellier, Montpellier, France., Brusselle GG; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.; Department of Epidemiology and Respiratory Medicine, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands., Busby J; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Canonica GW; Personalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Heffler E; Personalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Chapman KR; University of Toronto, Toronto, Ontario, Canada., Charriot J; PhyMedExp, University of Montpellier, CNRS, INSERM, CHU Montpellier, Montpellier, France., Christoff GC; Faculty of Public Health, Medical University, Sofia, Bulgaria., Chung LP; Fiona Stanley Hospital, Perth, Western Australia, Australia., Cosio BG; Son Espases University Hospital-IdISBa-Ciberes, Mallorca, Spain., Côté A; Department of Medicine, Laval University, Quebec City, Quebec, Canada., Costello RW; Department of Respiratory Medicine, Clinical Research Centre, Smurfit Building Beaumont Hospital, RCSI, Dublin, Ireland., Cushen B; Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland., Fingleton J; Capital and Coast District Health Board, Wellington, New Zealand., Fonseca JA; CINTESIS@RISE, MEDCIDS, Faculty of Medicine of the University of Porto, Porto, Portugal., Gibson PG; Australian Severe Asthma Network, Priority Research Centre for Healthy Lungs, University of Newcastle, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, New Lambton Heights, New South Wales, Australia., Heaney LG; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK., Huang EW; Department of Internal Medicine, Division of Pulmonary Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Iwanaga T; Kindai University Hospital, Osakasayama, Japan., Jackson DJ; Guy's Severe Asthma Centre, Guy's Hospital, King's College London, London, UK., Koh MS; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore., Lehtimäki L; Allergy Centre, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Máspero J; Clinical Research for Allergy and Respiratory Medicine, CIDEA Foundation, Buenos Aires, Argentina.; University Career of Specialists in Allergy and Clinical Immunology at the Buenos Aires University School of Medicine, Buenos Aires, Argentina., Mahboub B; Rashid hospital, Dubai Health Authority (DHA), Dubai, United Arab Emirates., Menzies-Gow AN; AstraZeneca, Cambridge, UK.; Lung Division, Royal Brompton & Harefield Hospital, London, UK., Mitchell PD; School of Medicine, Trinity College Dublin, Dublin, Ireland., Papadopoulos NG; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, UK.; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece., Papaioannou AI; 2nd Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, Attikon University Hospital, Athens, Greece., Perez-de-Llano L; Pneumology Service, Lucus Augusti University Hospital, EOXI Lugo, Monforte, Cervo, Spain., Perng DW; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan., Pfeffer PE; Department of Respiratory Medicine, Barts Health NHS Trust, London, UK.; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Popov TA; University Hospital St. Ivan Rilski, Sofia, Bulgaria., Porsbjerg CM; Department of Respiratory Medicine and Infectious Diseases, Research Unit, Bispebjerg Hospital, Copenhagen, Denmark., Rhee CK; Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Roche N; Department of Respiratory Medicine, APHP-Centre University Paris Cité, Cochin Hospital and Institute (UMR1016), Paris, France., Sadatsafavi M; Respiratory Evaluation Sciences Program, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada., Salvi S; Pulmocare Research and Education Foundation, Pune, India., Schmid JM; University Hospital of Aarhus, Aarhus, Denmark., Sheu CC; Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Sirena C; Severe Asthma Network Italy (SANI), Milan, Italy., Torres-Duque CA; CINEUMO, Respiratory Research Center, Fundación Neumológica Colombiana, Bogotá, Colombia.; Universidad de La Sabana, Chia, Colombia., Salameh L; Rashid hospital, Dubai Health Authority (DHA), Dubai, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Patel PH; Respiratory Medicine, Royal Brompton Hospital, London, UK., Ulrik CS; Department of Respiratory Medicine, Copenhagen University Hospital, Hvidovre, Denmark., Wang E; Department of Medicine, Division of Allergy and Clinical Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, Colorado, USA., Wechsler ME; Department of Medicine, NJH Cohen Family Asthma Institute, National Jewish Health, Denver, Colorado, USA., Price DB; Optimum Patient Care Global, Cambridge, UK.; Observational and Pragmatic Research Institute, Singapore, Singapore.; Division of Applied Health Sciences, Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK.

Publikováno v: Allergy [Allergy] 2024 Oct; Vol. 79 (10), pp. 2700-2716. Date of Electronic Publication: 2024 Jun 22.

Overcoming Barriers to Remission in Severe Eosinophilic Asthma: Two-Year Real-World Data With Benralizumab.

Autor: Jackson DJ; Guy's Severe Asthma Centre, Guy's & St Thomas' NHS Trust, London, UK.; School of Immunology & Microbial Sciences, King's College London, London, UK., Burhan H; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.; University of Liverpool, Liverpool, UK., Rupani H; University Hospital Southampton NHS Foundation Trust, Southampton, UK., Pfeffer PE; St. Bartholomew's Hospital, London, UK., Clifton IJ; University of Leeds, Leeds, UK., Faruqi S; Hull University Teaching Hospitals, Hull, UK., Dhariwal J; Guy's Severe Asthma Centre, Guy's & St Thomas' NHS Trust, London, UK., Patel P; Royal Brompton and Harefield Hospitals, London, UK., Morris T; AstraZeneca UK, London, UK., Lipworth J; AstraZeneca UK, London, UK., Watt M; AstraZeneca UK, London, UK., Lupton C; AstraZeneca UK, London, UK., Dube S; AstraZeneca UK, London, UK., Hickey J; OPEN Health, Marlow, UK., Nanzer AM; Guy's Severe Asthma Centre, Guy's & St Thomas' NHS Trust, London, UK.; School of Immunology & Microbial Sciences, King's College London, London, UK.

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2024 Oct; Vol. 54 (10), pp. 734-746. Date of Electronic Publication: 2024 Jul 31.

Twice-Yearly Depemokimab in Severe Asthma with an Eosinophilic Phenotype.

Autor: Jackson DJ; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Wechsler ME; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Jackson DJ; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Bernstein D; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Korn S; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Pfeffer PE; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Chen R; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Saito J; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., de Luíz Martinez G; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Dymek L; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Jacques L; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Bird N; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Schalkwijk S; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Smith D; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Howarth P; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.)., Pavord ID; From Guy's Severe Asthma Centre, Guy's and St. Thomas' NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King's College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) - all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin-Madison, Madison (Daniel J. Jackson); the University of Cincinnati College of Medicine and Bernstein Clinical Research Center, Cincinnati (D.B.); Clinical Research Center, Respiratory Medicine, IKF Pneumologie Mainz, Mainz, and Thoraxklinik Heidelberg, Heidelberg - both in Germany (S.K.); State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Joint International Research Laboratory of Respiratory Health, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China (R.C.); Fukushima Medical University, Fukushima, Japan (J.S.); Hospital Vithas Xanit Internacional, Málaga, Spain (G.L.M.); Centrum Medyczne Lucyna Andrzej Dymek, Strzelce Opolskie, Poland (L.D.); and GSK, Collegeville, PA (D.S.).

Publikováno v: The New England journal of medicine [N Engl J Med] 2024 Sep 09. Date of Electronic Publication: 2024 Sep 09.

Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study - PHOSP-COVID.

Autor: Elneima O; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Hurst JR; UCL Respiratory, Department of Medicine, University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK., Echevarria C; Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Quint JK; School of Public Health, Imperial College London, London, UK., Walker S; Asthma+Lung UK, London, UK., Siddiqui S; National Heart and Lung Institute, Imperial College London, London, UK., Novotny P; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Pfeffer PE; Department of Respiratory Medicine, Barts Health NHS Trust, London, UK.; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Brown JS; UCL Respiratory, Department of Medicine, University College London, London, UK., Shankar-Hari M; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., McAuley HJC; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Leavy OC; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.; Department of Population Health Sciences, University of Leicester, Leicester, UK., Shikotra A; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Singapuri A; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Sereno M; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Richardson M; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Saunders RM; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Harris VC; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Houchen-Wolloff L; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.; Centre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK., Greening NJ; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Harrison EM; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Docherty AB; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Lone NI; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Chalmers JD; University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Ho LP; MRC Translational Discovery Immunology Unit, University of Oxford, Oxford, UK.; NIHR Oxford BRC, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Horsley A; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Manchester University NHS Foundation Trust, Manchester, UK., Marks M; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.; Hospital for Tropical Diseases, University College London Hospital, London, UK., Poinasamy K; Asthma+Lung UK, London, UK., Raman B; NIHR Oxford BRC, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Evans RA; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK., Wain LV; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Sheikh A; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Brightling CE; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, University of Leicester, Leicester, UK.; Joint senior authors., De Soyza A; Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.; Joint senior authors., Heaney LG; Wellcome-Wolfson Institute for Experimental Medicine, Queens University Belfast, Belfast, UK.; Belfast Health and Social Care Trust, Belfast, UK.; Joint senior authors.

Publikováno v: ERJ open research [ERJ Open Res] 2024 Jul 15; Vol. 10 (4). Date of Electronic Publication: 2024 Jul 15 (Print Publication: 2024).

Impact of comorbidities on EQ-5D quality-of-life index in severe asthma.

Autor: Pfeffer PE; Barts Health NHS Trust, London, United Kingdom.; Queen Mary University of London, London, United Kingdom., Brown T; Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom., Chaudhuri R; Gartnavel General Hospital and University of Glasgow, Glasgow, United Kingdom., Faruqi S; Hull University Teaching Hospitals NHS Trust, Hull, United Kingdom., Gore R; Addenbrookes Hospital, Cambridge, United Kingdom., Heaney LG; Queen's University, Belfast, United Kingdom., Mansur AH; University Hospitals Birmingham NHS Trust, Birmingham, United Kingdom.; University of Birmingham, Birmingham, United Kingdom., Pantin T; Wythenshawe Hospital, Manchester, United Kingdom., Patel M; Derriford Hospital, Plymouth, United Kingdom., Rupani H; University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom., Siddiqui S; National Heart and Lung Institute, Imperial College, London, United Kingdom., Vyas A; Lancashire Teaching Hospitals NHS Foundation Trust, Preston, United Kingdom., Busby J; Centre for Public Health, Queen's University Belfast, Belfast, United Kingdom.

Publikováno v: The journal of allergy and clinical immunology. Global [J Allergy Clin Immunol Glob] 2024 May 31; Vol. 3 (3), pp. 100286. Date of Electronic Publication: 2024 May 31 (Print Publication: 2024).