Zobrazeno 1 - 10
of 1 650
pro vyhledávání: '"PDGF‐BB"'
Autor:
Sheng Liu, Xiaona Chu, Jill L. Reiter, Xuhong Yu, Fang Fang, Patrick McGuire, Hongyu Gao, Yunlong Liu, Jun Wan, Yue Wang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Mesenchymal stem cells (MSCs) are multipotent stem cells that are under investigation for use in clinical trials because they are capable of self-renewal and differentiating into different cell types under defined conditions. None
Externí odkaz:
https://doaj.org/article/6b8dc3d28c0a48908c4edd90c47ea52a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Atherosclerosis is rare in internal thoracic arteries (ITA) even in patients with severe atherosclerotic coronary artery (ACA) disease. To explore cellular differences, ITA SMC from 3 distinct donors and ACA SMC from 3 distinct donors were g
Externí odkaz:
https://doaj.org/article/0fa4856e1ea54e97a8a918d85f27ba31
Autor:
Fei Li, Chuwei Zhang, Xiaoping Zhong, Bo Li, Mengnan Zhang, Wanqian Li, Lifei Zheng, Xinghua Zhu, Shixuan Chen, Yi Zhang
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101237- (2024)
Diabetic foot ulcers, pressure ulcers, and bedsores can easily develop into chronic wounds with bacterial infections, complicating wound healing. This work reports a two-step strategy for treating infected chronic wounds. Firstly, LL37 mimetic peptid
Externí odkaz:
https://doaj.org/article/5e9f0aa48503458cb10661215ea6efaa
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Hormonal necrosis of the femoral head is caused by long-term use of glucocorticoids and other causes of abnormal bone metabolism, lipid metabolism imbalance and blood microcirculation disorders in the femoral head, resulting in bone trabecul
Externí odkaz:
https://doaj.org/article/add522645a944d6697f8515f62dfec1e
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 282-297 (2024)
Musculoskeletal injuries and bone defects represent a significant clinical challenge, necessitating innovative approaches for effective bone tissue regeneration. In this study, we investigated the potential of harnessing periosteal stem cells (PSCs)
Externí odkaz:
https://doaj.org/article/ea66f23326da4cf083d72b05262e0d2f
Autor:
Natalie E. King, Jo-Maree Courtney, Lachlan S. Brown, Alastair J. Fortune, Nicholas B. Blackburn, Jessica L. Fletcher, Jake M. Cashion, Jana Talbot, Alice Pébay, Alex W. Hewitt, Gary P. Morris, Kaylene M. Young, Anthony L. Cook, Brad A. Sutherland
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood–brain barrier function, and pericyte dysfunction may contribute to the pathophysiolog
Externí odkaz:
https://doaj.org/article/c8c8c85bb5db476ea1a3b1f8afc26262
Autor:
Takuto Tachita, Masaki Ri, Sho Aoki, Arisa Asano, Takashi Kanamori, Haruhito Totani, Shiori Kinoshita, Yu Asao, Tomoko Narita, Ayako Masaki, Asahi Ito, Shigeru Kusumoto, Hirokazu Komatsu, Shinsuke Iida
Publikováno v:
Cancer Medicine, Vol 13, Iss 14, Pp n/a-n/a (2024)
Abstract Multiple myeloma (MM) is an incurable B‐cell malignancy often accompanied by profound immunodeficiency. Lenalidomide (Len) is an immunomodulatory drug that exerts promising therapeutic effects on MM through the immune system. However, pred
Externí odkaz:
https://doaj.org/article/5be8624e698c4954a681a98d8ab053ef
Autor:
Jianguo Xu, Li Bian, Dingyun You, Ziliang Li, Tingting Wang, Yiting Li, Xiaobin Ren, Yongwen He
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract The tumor microenvironment and cancer-associated fibroblasts (CAFs) play crucial roles in tumor development, and their metabolic coupling remains unclear. Clinical data showed a positive correlation between PDGF-BB, CAFs, and glycolysis in t
Externí odkaz:
https://doaj.org/article/fa3c79e82e8d410393c1d23044ef70e6
Autor:
Zhenxing Sun, Yu Cai, Yihan Chen, Qiaofeng Jin, Ziming Zhang, Li Zhang, Yuman Li, Lei Huang, Jing Wang, Yali Yang, Qing Lv, Zhengyang Han, Mingxing Xie, Xiangming Zhu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Ultrasound-targeted microbubble destruction (UTMD) has emerged as a promising strategy for the targeted delivery of bone marrow mesenchymal stem cells (MSCs) to the ischemic myocardium. However, the limited migration capacity and
Externí odkaz:
https://doaj.org/article/2c8e8fd63b694d11b257a4d8940aecd3
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