Zobrazeno 1 - 10
of 159
pro vyhledávání: '"PD1/PDL1"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Immunotherapy is a promising treatment for cancer that aims to boost the immune system’s response to cancer cells. This can be achieved by blocking Programmed cell death protein 1/Programmed death-ligand 1 (PD1/PDL1), which activates T cel
Externí odkaz:
https://doaj.org/article/52230b81264444118335da2a43836cd7
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundTertiary lymphoid structures (TLS) play a crucial role in tumor immunity, yet their relationship with the efficacy of immune checkpoint inhibitors (ICI) in cancer therapy is not fully understood. This study aims to systematically evaluate h
Externí odkaz:
https://doaj.org/article/2b0f4e5b7f214cd5b1f5e6d7a4833373
Autor:
Fuxin Xue, Xitong Ren, Chaoying Kong, Jianfeng Wang, Linlin Liu, Junli Hu, Na Shen, Zhaohui Tang
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101239- (2024)
Immune checkpoint blockade (ICB) therapy, particularly PD1/PDL1 inhibition, has demonstrated success in bolstering durable responses in patients. However, the response rate remains below 30 %. In this study, we developed a polymeric bispecific antibo
Externí odkaz:
https://doaj.org/article/d8ac2ed7892c4d5c80a3a4054ee33766
Autor:
Peishan Li, Ying Xie, Jinling Wang, Chunjie Bao, Jialun Duan, Yixuan Liu, Qian Luo, Jiarui Xu, Yuxin Ren, Min Jiang, Jianwei Li, Haitao Guo, Huihui Zhao, Guiling Wang, Yanqin Liang, Wanliang Lu
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 466-481 (2024)
Cancer patients by immune checkpoint therapy have achieved long-term remission, with no recurrence of clinical symptoms of cancer for many years. Nevertheless, more than half of cancer patients are not responsive to this therapy due to immune exhaust
Externí odkaz:
https://doaj.org/article/fb2dd4b5937b460992e27759f0844669
Autor:
Matías Muñoz-Medel, Mauricio P. Pinto, Lauren Goralsky, Mónica Cáceres, Franz Villarroel-Espíndola, Patricio Manque, Andrés Pinto, Benjamin Garcia-Bloj, Tomas de Mayo, Juan A. Godoy, Marcelo Garrido, Ignacio N. Retamal
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Porphyromonas gingivalis (P. gingivalis) is a gram-negative oral pathogen associated with chronic periodontitis. Previous studies have linked poor oral health and periodontitis with oral cancer. Severe cases of periodontal disease can result in advan
Externí odkaz:
https://doaj.org/article/c3e2ec22d280440da14f186d236c40eb
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27103- (2024)
The aim of this study was to present current research trends on the synergistic use of radiotherapy and immunotherapy (IRT) for cancer treatment. On March 1, 2023, we conducted a literature search for IRT papers using the Web of Science database. We
Externí odkaz:
https://doaj.org/article/4c1938cfb9d04b29a73eea925c6ddc2f
Akademický článek
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Akademický článek
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Autor:
Shi Tang, Xiaofeng Cong, Dan Zheng, Chen Chen, Zengguang Liu, Jie Gao, Huimin Zhang, Youhao Zhang, Ziling Liu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundConcurrent programmed death 1 (PD-1) or programmed death ligand 1 (PD-L1) inhibitors with sequential chemoradiotherapy (SCRT) have been reported in only a limited number of studies involving patients with unresectable stage III non-small-ce
Externí odkaz:
https://doaj.org/article/da52755276d145d18c4d189419afe374
Autor:
Yanhao Liu, Lan Yu, Yanjiao Liang, Xi Cheng, Shu Jiang, Haiming Yu, Zhen Zhang, Linlin Lu, Baozhen Qu, Yuxian Chen, Xiaotao Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundImmunotherapy for lung cancer has been a hot research area for years. This bibliometric analysis was intended to present research trends on melanoma immunotherapy.MethodOn April 1, 2022, the authors identified 2,109 papers on melanoma immun
Externí odkaz:
https://doaj.org/article/50fd5f748fe14106856c37d0d2b99394