Gut microbiome influences efficacy of Endostatin combined with PD-1 blockade against colorectal cancer

Autor: Jie Xu, Yaomei Tian, Binyan Zhao, Die Hu, Siwen Wu, Jing ma, Li Yang

Publikováno v: Molecular Biomedicine, Vol 5, Iss 1, Pp 1-17 (2024)

Abstract The combination of anti-angiogenic drugs and immune checkpoint inhibitors (ICIs) in the treatment of tumors is emerging as a way to improve ICIs-resistant tumor therapy. In addition, gut microbes (GMs) are involved in angiogenesis in the tum

Externí odkaz: https://doaj.org/article/bbf81cf0381a469caa7c04489c0eb4e1

PD‐1 blockade enhances the effect of targeted chemotherapy on locally advanced pMMR/MSS colorectal cancer.

Autor: Pei, Fengyun^1,2 (AUTHOR), He, Wan³ (AUTHOR), Duan, Yinghua⁴ (AUTHOR), Yao, Qijun^1,2 (AUTHOR), Zhao, Yandong⁵ (AUTHOR), Fan, Xinjuan⁵ (AUTHOR), Liu, Shuai⁶ (AUTHOR), Chen, Haiyang⁶ (AUTHOR), He, Fang⁶ (AUTHOR), Liu, Tingzhi⁷ (AUTHOR), Chen, Jiaoting⁷ (AUTHOR), Zheng, Yijia⁷ (AUTHOR), Li, Heping⁸ (AUTHOR), Guo, Xiaofang⁸ (AUTHOR), Shi, Lishuo⁹ (AUTHOR), Ling, Li¹⁰ (AUTHOR), Chen, Yaoxu¹¹ (AUTHOR), He, Jiapeng¹¹ (AUTHOR), Liu, Miao¹¹ (AUTHOR), Huang, Mengli¹¹ (AUTHOR)

Publikováno v: Cancer Medicine. Jun2024, Vol. 13 Issue 12, p1-12. 12p.

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GSH-responsive polymeric micelles-based augmented photoimmunotherapy synergized with PD-1 blockade for eliciting robust antitumor immunity against colon tumor.

Autor: Huang, Chenlu^1,2 (AUTHOR), Yang, Xinyu^1,2 (AUTHOR), Li, Huidong² (AUTHOR), Zhang, Li^1,2 (AUTHOR), Guo, Qing^1,2 (AUTHOR), Yu, Qingyu^1,2 (AUTHOR), Wang, Hai^1,2 (AUTHOR), Zhang, Linhua^1,2 (AUTHOR) zhanglinhua@bme.pumc.edu.cn, Zhu, Dunwan^1,2 (AUTHOR) zhudunwan@bme.pumc.edu.cn

Publikováno v: Journal of Nanobiotechnology. 9/5/2024, Vol. 22 Issue 1, p1-14. 14p.