Zobrazeno 1 - 10
of 39
pro vyhledávání: '"PD-1: programmed death 1"'
Autor:
Maria-Luisa del Rio, Carla Yago-Diez de Juan, Giovanna Roncador, Eduardo Caleiras, Ramón Álvarez-Esteban, José Antonio Pérez-Simón, Jose-Ignacio Rodriguez-Barbosa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionA high frequency of mutations affecting the gene encoding Herpes Virus Entry Mediator (HVEM, TNFRSF14) is a common clinical finding in a wide variety of human tumors, including those of hematological origin.MethodsWe have addressed how HV
Externí odkaz:
https://doaj.org/article/d45f1aac1da2426b84b5c0a30178393d
Autor:
Yuichiro Asai, Hirofumi Chiba, Hirotaka Nishikiori, Ryuta Kamekura, Hayato Yabe, Shun Kondo, Satsuki Miyajima, Katsunori Shigehara, Shingo Ichimiya, Hiroki Takahashi
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background T follicular helper (Tfh) cells have been identified as a new category of helper T cells, which express CXCR5 on their surface and induce the production of antigen-specific antibodies. Many investigations have found morbid prolife
Externí odkaz:
https://doaj.org/article/4a285151f3bc4b11b347995c4f5a41ab
Autor:
Fei Chu, Nicholas J. Skertich, Jeffrey A. Borgia, Imad Tarhoni, Stephen Szajek, Mary Beth Madonna
Publikováno v:
Surgery Open Science, Vol 6, Iss, Pp 10-14 (2021)
Surgery Open Science
Surgery Open Science
Background: Inhibition of the programmed death ligand 1, programmed death 1 pathway has been successfully used for treatment of multiple advanced adult cancers. However, its use in pediatric osteosarcoma is still in its infancy. In this study, we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4b311880ebd1fc0b8ba946d799acef
http://www.sciencedirect.com/science/article/pii/S2589845021000129
http://www.sciencedirect.com/science/article/pii/S2589845021000129
Autor:
Mahmoud Ali, Amina Adil, Sana Jeffreys, Rahul Sawlani, A. Jamil Tajik, Omar M Cheema, Patrycja Galazka
Publikováno v:
JACC Case Reports
A 59-year-old woman with history of skin melanoma and complete excision presented with palpitations. Transthoracic echocardiogram revealed right atrial mass attached to interatrial septum. Cardiac magnetic resonance was suggestive of metastatic melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b617b109c56c3186d952fd27e819de
http://europepmc.org/articles/PMC8511469
http://europepmc.org/articles/PMC8511469
Autor:
Hao Wang, Lei Wang, Keyi Jia, Yu Liu, Sha Zhao, Wei Li, Caicun Zhou, Minlin Jiang, Bin Chen, Yayi He
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Genomic instability remains an enabling feature of cancer and promotes malignant transformation. Alterations of DNA damage response (DDR) pathways allow genomic instability, generate neoantigens, upregulate the expression of programmed death ligand 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe73202674a833d134ec811bcbf7332
https://doi.org/10.1016/j.apsb.2021.01.003
https://doi.org/10.1016/j.apsb.2021.01.003
Autor:
Go, Du-Min, Lee, Seung Hyun, Lee, Su-Hyung, Woo, Sang-Ho, Kim, Kibyeong, Kim, Kyeongdae, Park, Kyu Seong, Park, Jong-Hwan, Ha, Sang-Jun, Kim, Woo Ho, Choi, Jae-Hoon, Kim, Dae-Yong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Helicobacter pylori has been reported to modulate local immune responses to colonize persistently in gastric mucosa. Although the induced expression of programmed cell death ligand 1 (PD-L1) has been suggested as an immune modulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef8f6fcf149fca0f5b3eb28847252f65
http://europepmc.org/articles/PMC8267570
http://europepmc.org/articles/PMC8267570
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 750-762 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The protein tyrosine phosphatase Src homology phosphotyrosyl phosphatase 2 (SHP2) is implicated in various cancers, and targeting SHP2 has become a promising therapeutic approach. We herein described a robust cross-validation high-throughput screenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114cd1e4de1acb4de79002f71ffaa0be
https://doi.org/10.1016/j.apsb.2020.10.021
https://doi.org/10.1016/j.apsb.2020.10.021
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 55-76 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 55-76 (2021)
Background & Aims Communication between T cells and the intestinal epithelium is altered in many diseases, causing T-cell activation, depletion, or recruitment, and disruption of the epithelium. We hypothesize that activation of T cells regulates epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450cac7e7a2afdff8746af24c48114ab
https://doi.org/10.1016/j.jcmgh.2020.07.004
https://doi.org/10.1016/j.jcmgh.2020.07.004
Akademický článek
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Publikováno v:
JAAD Case Reports, Vol 6, Iss 10, Pp 1045-1047 (2020)
JAAD Case Reports
JAAD Case Reports
Immune checkpoint inhibitors, including pembrolizumab, are novel immunotherapeutic agents that have revolutionized cancer therapy. With increasing use of immunotherapy, early recognition and prompt treatment of associated adverse events are critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74f55c449d9e4c7d71b84ed7a71a9b0
https://doi.org/10.1016/j.jdcr.2020.03.007
https://doi.org/10.1016/j.jdcr.2020.03.007