Zobrazeno 1 - 10
of 11
pro vyhledávání: '"PCSK9, proprotein convertase subtilisin kexin 9"'
Autor:
Stephen D. Wiviott, Michael A. Blazing, Andrew M. Tershakovec, Robert M. Califf, Eugene Braunwald, Charles S. Fuchs, Jeong-Gun Park, Robert P. Giugliano, Christopher P. Cannon, Wolfram Goessling, Baris Gencer, Thomas Musliner
Publikováno v:
JACC. CardioOncology, Vol 2, Iss 3, Pp 385-396 (2020)
JACC: CardioOncology
JACC: CardioOncology
Background An increased risk of malignancy was reported with simvastatin/ezetimibe in 1,873 patients in the SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) trial. Objectives The purpose of this study was to clarify this unexpected finding in a la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a92a69ee6ec78427fa63df4afe4361
https://doi.org/10.1016/j.jaccao.2020.07.008
https://doi.org/10.1016/j.jaccao.2020.07.008
Autor:
Akihiro Inazu, Masa-aki Kawashiri, Atsushi Nohara, Hiroshi Mabuchi, Kenshi Hayashi, Hayato Tada, Masakazu Yamagishi
Publikováno v:
Practical Laboratory Medicine, Vol 1, Iss, Pp 22-27 (2015)
Practical Laboratory Medicine
Practical Laboratory Medicine
Objectives It is well known that familial hypercholesterolemia (FH) is a common inherited disorder that can markedly elevate the level of plasma LDL cholesterol. However, little data exists regarding the clinical impact of the plasma triglyceride (TG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bbf21b47807de136a370169a68a2b9
https://doi.org/10.1016/j.plabm.2015.03.001
https://doi.org/10.1016/j.plabm.2015.03.001
Autor:
Mafalda Raposo, Patrícia Mendes, Manuela Lima, Teresa Cymbron, Ana Margarida Medeiros, Nadiya Kazachkova, Jácome Bruges-Armas, Amanda Ramos, Mafalda Bourbon
Publikováno v:
Meta Gene
Familial hypercholesterolemia (FH) is an autosomal dominant disorder of the cholesterol metabolism, which constitutes a risk factor for coronary arterial disease (CAD). In the Azores Islands (Portugal), where mortality from CAD doubles its rate compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a249a4d9e8d0a7db9dea3440326049d9
Autor:
Jacqueline de Graaf, George Thanassoulis, Ken Williams, Curt D. Furberg, Allan D. Sniderman, Patrick R. Lawler
Publikováno v:
Clinical Science, 122, 369-73
Clinical Science (London, England : 1979)
Clinical Science, 122, 8, pp. 369-73
Clinical Science (London, England : 1979)
Clinical Science, 122, 8, pp. 369-73
Item does not contain fulltext Primary prevention of cardiovascular disease is governed at present by the risk factor model for cardiovascular events, a model which is widely accepted by physicians and professional associations, but which has importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d63b88d85b3ce26ab717638c2eac3fb
https://doi.org/10.1042/CS20110449
https://doi.org/10.1042/CS20110449
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 755-762 (2014)
FEBS Open Bio
FEBS Open Bio
Highlights • Quercetin-3-glucoside can increase LDLR expression by hepatocytes. • Quercetin-3-glucoside can reduce PCSK9 secretion by hepatocytes. • Quercetin-3-glucoside can down regulate sortilin expression. • Quercetin-3-glucoside can incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87f6b700221cf8c6a3f7779a511f3be
Autor:
Saud A; Department of Pharmacology and Therapeutics, College of Medicine, University of Kufa, Najaf, Iraq., Ali N; Department of Pharmacology, College of Medicine, University of Basra, Basra, Iraq., Gali F; Department of Pharmacology &Therapeutics, Faculty of Medicine, University of Kufa, Najaf, Iraq., Qassam H; Department of Pharmacology &Therapeutics, Faculty of Medicine, University of Kufa, Najaf, Iraq., Hadi NR; Department of Pharmacology &Therapeutics, Faculty of Medicine, University of Kufa, Najaf, Iraq.
Publikováno v:
Journal of medicine and life [J Med Life] 2023 May; Vol. 16 (5), pp. 759-765.
Autor:
German CA; Section of Cardiology, Department of Medicine, University of Chicago, Chicago, IL, USA., Baum SJ; Department of Integrated Medical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA., Ferdinand KC; Tulane Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, LA, USA., Gulati M; Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Polonsky TS; Section of Cardiology, Department of Medicine, University of Chicago, Chicago, IL, USA., Toth PP; Cicarrone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD and CGH Medical Center, Sterling, IL, USA., Shapiro MD; Section on Cardiovascular Medicine, Center for Prevention of Cardiovascular Disease, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Publikováno v:
American journal of preventive cardiology [Am J Prev Cardiol] 2022 Nov 16; Vol. 12, pp. 100432. Date of Electronic Publication: 2022 Nov 16 (Print Publication: 2022).
Autor:
Giugliano RP; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Gencer B; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Wiviott SD; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Park JG; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Fuchs CS; Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut, USA., Goessling W; Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts, USA., Musliner TA; Merck, Kenilworth, New Jersey, USA., Tershakovec AM; Merck, Kenilworth, New Jersey, USA., Blazing MA; Duke Clinical Research Institute, Durham, North Carolina, USA., Califf R; Verily Life Sciences and Google Health, South San Francisco, California, USA., Cannon CP; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Braunwald E; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Publikováno v:
JACC. CardioOncology [JACC CardioOncol] 2020 Sep 15; Vol. 2 (3), pp. 385-396. Date of Electronic Publication: 2020 Sep 15 (Print Publication: 2020).
Autor:
Tada H; Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, 920-8641 Kanazawa, Japan., Kawashiri MA; Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, 920-8641 Kanazawa, Japan., Nohara A; Department of Lipidology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan., Inazu A; Department of Laboratory Science, Molecular Biochemistry and Molecular Biology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan., Mabuchi H; Department of Lipidology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan., Yamagishi M; Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, 920-8641 Kanazawa, Japan., Hayashi K; Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, 920-8641 Kanazawa, Japan.
Publikováno v:
Practical laboratory medicine [Pract Lab Med] 2015 Mar 13; Vol. 1, pp. 22-27. Date of Electronic Publication: 2015 Mar 13 (Print Publication: 2015).
Autor:
Cymbron T; Centre of Research in Natural Resources (CIRN), Department of Biology, University of the Azores, 9501-801 Ponta Delgada, Azores, Portugal ; Institute for Molecular and Cell Biology (IBMC), University of Porto, 4150-180 Porto, Portugal., Mendes P; The Azores School of New Technologies (ENTA), 9504-540 Ponta Delgada, Azores, Portugal., Ramos A; Centre of Research in Natural Resources (CIRN), Department of Biology, University of the Azores, 9501-801 Ponta Delgada, Azores, Portugal ; Institute for Molecular and Cell Biology (IBMC), University of Porto, 4150-180 Porto, Portugal., Raposo M; Centre of Research in Natural Resources (CIRN), Department of Biology, University of the Azores, 9501-801 Ponta Delgada, Azores, Portugal ; Institute for Molecular and Cell Biology (IBMC), University of Porto, 4150-180 Porto, Portugal., Kazachkova N; Centre of Research in Natural Resources (CIRN), Department of Biology, University of the Azores, 9501-801 Ponta Delgada, Azores, Portugal ; Institute for Molecular and Cell Biology (IBMC), University of Porto, 4150-180 Porto, Portugal., Medeiros AM; Grupo de Investigação Cardiovascular, Unidade I&D, Departamento de Promoção da Saúde e Prevenção de Doenças Não Transmissíveis, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-040 Lisboa, Portugal ; Centre for Biodiversity, Functional and Integrative Genomics (BioFIG), Faculty of Sciences, University of Lisboa, 1749-016 Lisboa, Portugal., Bruges-Armas J; Institute for Molecular and Cell Biology (IBMC), University of Porto, 4150-180 Porto, Portugal ; Specialized Service of Epidemiology and Molecular Biology (SEEBMO), Hospital of Santo Espírito, 9700-049 Angra do Heroísmo, Azores, Portugal., Bourbon M; Grupo de Investigação Cardiovascular, Unidade I&D, Departamento de Promoção da Saúde e Prevenção de Doenças Não Transmissíveis, Instituto Nacional de Saúde Dr. Ricardo Jorge, 1649-040 Lisboa, Portugal ; Centre for Biodiversity, Functional and Integrative Genomics (BioFIG), Faculty of Sciences, University of Lisboa, 1749-016 Lisboa, Portugal., Lima M; Centre of Research in Natural Resources (CIRN), Department of Biology, University of the Azores, 9501-801 Ponta Delgada, Azores, Portugal ; Institute for Molecular and Cell Biology (IBMC), University of Porto, 4150-180 Porto, Portugal.
Publikováno v:
Meta gene [Meta Gene] 2014 Sep 14; Vol. 2, pp. 638-45. Date of Electronic Publication: 2014 Sep 14 (Print Publication: 2014).