Zobrazeno 1 - 10
of 1 301
pro vyhledávání: '"PCAF"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Dysregulation in histone acetylation, a significant epigenetic alteration closely associated with major pathologies including cancer, promotes tumorigenesis, inactivating tumor-suppressor genes and activating oncogenic pathways. A
Externí odkaz:
https://doaj.org/article/9ad56304106049e5925bc82ddd268493
Autor:
Jinteng Li, Feng Ye, Xiaojun Xu, Peitao Xu, Peng Wang, Guan Zheng, Guiwen Ye, Wenhui Yu, Zepeng Su, Jiajie Lin, Yunshu Che, Zhidong Liu, Pei Feng, Qian Cao, Dateng Li, Zhongyu Xie, Yanfeng Wu, Huiyong Shen
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Sustained inflammatory invasion leads to joint damage and progressive disability in several autoimmune rheumatic diseases. In recent decades, targeting M1 macrophage polarization has been suggested as a promising therapeutic strategy for aut
Externí odkaz:
https://doaj.org/article/3378b6b45fa14d5697610c946e2d80de
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 13, Iss 1, Pp 1-10 (2022)
Abstract Background Intestinal barrier plays key roles in maintaining intestinal homeostasis. Inflammation damage can severely destroy the intestinal integrity of mammals. This study was conducted to investigate the protective effects of embelin and
Externí odkaz:
https://doaj.org/article/bd1dd1d5767d479fb1b147258cdf8925
Akademický článek
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Publikováno v:
Biotropia: The Southeast Asian Journal of Tropical Biology, Vol 30, Iss 1 (2023)
Stress conditions will trigger the histone hyperacetylation process due to histone acetyltransferase p300/CBP (HAT PCAF) constantly transfers acetyl groups from acetyl-CoA to conserved lysine residues on histone proteins to form ε-N-acetyllysine. Th
Externí odkaz:
https://doaj.org/article/5b25b5a0a2fb4df4ac0e4bc760981e46
Autor:
Maria Alicia Carrillo-Sepulveda, Nicole Maddie, Christina Mary Johnson, Cameron Burke, Osina Lutz, Bamwa Yakoub, Benjamin Kramer, Dhandevi Persand
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-14 (2022)
Abstract Background Advanced type 2 diabetes mellitus (T2DM) accelerates vascular smooth muscle cell (VSMC) dysfunction which contributes to the development of vasculopathy, associated with the highest degree of morbidity of T2DM. Lysine acetylation,
Externí odkaz:
https://doaj.org/article/ccd9b748defa44ee8daed35c47f10257
Publikováno v:
Current Research in Environmental Sustainability, Vol 6, Iss , Pp 100232- (2023)
Because of legislation and rising public pressure, financial institutions have begun to estimate and publish their financed greenhouse gas emissions. Such emissions are indirect from financial institutions' own greenhouse gas emissions and result fro
Externí odkaz:
https://doaj.org/article/4bef9c00561745ba8b05db8c147a28dc
Autor:
Yin‐Wei Cheng, Fa‐Min Zeng, Da‐Jia Li, Shao‐Hong Wang, Jian‐Zhong He, Zhen‐Chang Guo, Ping‐Juan Nie, Zhi‐Yong Wu, Wen‐Qi Shi, Bing Wen, Xiu‐E Xu, Lian‐Di Liao, Zhi‐Mao Li, Jian‐Yi Wu, Jun Zhan, Hong‐Quan Zhang, Zhi‐Jie Chang, Kai Zhang, Li‐Yan Xu, En‐Min Li
Publikováno v:
Cancer Communications, Vol 41, Iss 12, Pp 1398-1416 (2021)
Abstract Background Fascin is crucial for cancer cell filopodium formation and tumor metastasis, and is functionally regulated by post‐translational modifications. However, whether and how Fascin is regulated by acetylation remains unclear. This st
Externí odkaz:
https://doaj.org/article/396cbf9cf8724588809cbca5a4d2628a
Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The development and growth of a normal prostate gland, as well as its physiological functions, are regulated by the actions of androgens through androgen receptor (AR) signaling which drives multiple cellular processes including transcription, cellul
Externí odkaz:
https://doaj.org/article/88105c099a964bebbd30375835aee159