Zobrazeno 1 - 10
of 325
pro vyhledávání: '"PC Nowell"'
Publikováno v:
Blood. 81:2714-2722
Bone marrow (BM) cells from a child with an immature (CD3-) acute T lymphoblastic leukemia (T-ALL) bearing no chromosomal abnormalities failed to grow in long-term culture in the presence or absence of recombinant human (rh) growth factors but could
Autor:
J Goldman, D. F. Friedman, J Manz, Leslie E. Silberstein, Jonni S. Moore, J Erikson, PC Nowell
Publikováno v:
Blood. 80:2287-2297
Chronic lymphocytic leukemia of B-cell origin (B-CLL) is generally thought to arise by neoplastic transformation of B lymphocytes, which express CD5 and have features of an early stage of B-cell differentiation. To study isotype-switched B-CLL as a p
Publikováno v:
Blood. 80:2287-2297
Chronic lymphocytic leukemia of B-cell origin (B-CLL) is generally thought to arise by neoplastic transformation of B lymphocytes, which express CD5 and have features of an early stage of B-cell differentiation. To study isotype-switched B-CLL as a p
Autor:
CR Suarez, Charles M. Rubin, Diane C. Arthur, BJ Lange, B Bostrom, ES Baum, PC Nowell, Janet Rowley, James B. Nachman, William G. Woods
Publikováno v:
Blood. 78:2982-2988
We have studied 20 children with therapy-related myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) who were 3 months to 16 years old at diagnosis of their primary neoplasm and 1 to 24 years old at diagnosis of their secondary neoplasm. T
Autor:
R O'Connor, A Cesano, B Lange, J Finan, PC Nowell, SC Clark, SC Raimondi, G Rovera, D Santoli
Publikováno v:
Blood. 77:1534-1545
Cells from 10 cases of childhood acute T-lymphoblastic leukemia (T-ALL) were cultured in the presence of recombinant human interleukins (rhIL) or colony-stimulating factors (CSF) to analyze their growth factor requirements and differentiative potenti
Publikováno v:
Blood. 75:82-87
A truncated granulocyte-macrophage colony-stimulating factor (GM-CSF) allele on a putative 5q- chromosome of HL-60 cells was cloned and, by comparison with counterpart normal sequences, analyzed for clues to molecular mechanisms facilitating rearrang
Publikováno v:
Blood. 85(8)
Translocations involving chromosome 8 at band q24 and one of the Ig loci on chromosomes 14q32, 22q11, and 2p11 are the hallmark of Burkitt's lymphoma (BL). It has been previously observed that the exact localization of the breakpoints at chromosome 8
Autor:
Le, Silberstein, Lc, Jefferies, Goldman J, Friedman D, Js, Moore, Pc, Nowell, Roelcke D, Pruzanski W, jean roudier, Gj, Silverman
Publikováno v:
Europe PubMed Central
To investigate the molecular basis of the autoimmune response to the related i and I carbohydrate antigens, we studied cold agglutinins (CA) from B-cell clones and from the peripheral circulation of patients with lymphoproliferative syndromes. Sequen
Publikováno v:
Blood. 66(2)
Blood smears stained with Wright-Giemsa were obtained from 124 patients with pathologically confirmed cutaneous T cell lymphoma (CTCL), 70 patients with various other cutaneous disorders, and ten healthy adult volunteers. These were examined in a bli
Publikováno v:
Blood. 71(4)
The consistent occurrence of T cell abnormalities in patients with B cell chronic lymphocytic leukemia (B-CLL) suggest that the non- neoplastic host T cells may be involved in the pathogenesis of this B cell neoplasm. Because potential defects of imm