Zobrazeno 1 - 10
of 238
pro vyhledávání: '"PC, Phosphatidylcholine"'
Autor:
Fumio Sakane, Fumi Hoshino
Publikováno v:
Biochemical and Biophysical Research Communications
The clathrin coat assembly protein AP180 drives endocytosis, which is crucial for numerous physiological events, such as the internalization and recycling of receptors, uptake of neurotransmitters and entry of viruses, including SARS-CoV-2, by intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486bafc8e128e9f14b907481315a7d43
https://doi.org/10.1016/j.bbrc.2021.11.097
https://doi.org/10.1016/j.bbrc.2021.11.097
Autor:
Fei Luo, Eriks Smagris, Sarah A. Martin, Goncalo Vale, Jeffrey G. McDonald, Justin A. Fletcher, Shawn C. Burgess, Helen H. Hobbs, Jonathan C. Cohen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 879-899 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 879-899 (2022)
Background & Aims: Substitution of lysine for glutamic acid at residu 167 in Transmembrane 6 superfamily member 2 (TM6SF2) is associated with fatty liver disease and reduced plasma lipid levels. Tm6sf2-/- mice replicate the human phenotype but were n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c501eab0983bab28ced1482110d3291c
http://europepmc.org/articles/PMC8804273
http://europepmc.org/articles/PMC8804273
Autor:
Lu Tian, Wanfang Li, Jinfeng Wei, Zhi Zhou, Yanhua Chen, Zhonghua Wang, Wenqing Fu, Yaqi Liu, Baili Wang, Bingshu He, Meiling Huo, Jianzhen Xia, Zeper Abliz
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3665-3677 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy (DN) is vital for more accurate understanding the molecular pathological signature and developing novel therapeutic strategies. In the present study, a spatial-reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e36a0724bd8a167963aba4a72cb2332
http://www.sciencedirect.com/science/article/pii/S2211383521001799
http://www.sciencedirect.com/science/article/pii/S2211383521001799
Autor:
David A. Frank, Isidora Tošić
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is activated constitutively in a wide array of human cancers. It is an appealing molecular target for novel therapy as it directly regulates expression of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fc1e221705a2edcb47149735290583
http://europepmc.org/articles/PMC8569436
http://europepmc.org/articles/PMC8569436
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3060-3091 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation and destruction of the lung air-blood barrier, leading to irreversible and substantial respiratory function damage. Patients with coronavirus disease 2019 (COVID-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7076f0b91326b1dc05f8b3eaf861f6
https://doi.org/10.1016/j.apsb.2021.04.023
https://doi.org/10.1016/j.apsb.2021.04.023
Autor:
Nicole D. Bouvy, Marion J.J. Gijbels, Audrey C. H. M. Jongen, Hong Liu, Ron M. A. Heeren, Jianhua Cao, Benjamin Balluff, Jarno Melenhorst
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 35-41 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab, 20, 35-41. Elsevier
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, 20, 35-41. Elsevier BV
Journal of Mass Spectrometry and Advances in the Clinical Lab, 20, 35-41. Elsevier
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, 20, 35-41. Elsevier BV
Highlights • Lipids change overtime in normal fascial healing in the early post-surgery period. • Specific lipid species are correlated with the changes of inflammation cells and fibroblasts. • Lipid species in the present study are considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba480b5cb39e32e02e96d7e35c859f4
https://doi.org/10.1016/j.jmsacl.2021.06.002
https://doi.org/10.1016/j.jmsacl.2021.06.002
Autor:
Richard A. Yost, Vanessa Y. Rubio, Hoda Safari Yazd, Timothy J. Garrett, Casey A. Chamberlain
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 11-24 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • LC-HRMS Metabolomics and lipidomics applied in X-chromosome deletion disorders. • Partial or complete deletion of the X chromosome is a very rare condition. • Neural progenitor cells from a patient with a 7.3 megabase deletion at X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09943261b4913c7a499e6c4602a9449
http://www.sciencedirect.com/science/article/pii/S2667145X21000092
http://www.sciencedirect.com/science/article/pii/S2667145X21000092
Autor:
Aidan J. McGlinchey, Olivier Govaere, Dawei Geng, Vlad Ratziu, Michael Allison, Jerome Bousier, Salvatore Petta, Claudia de Oliviera, Elisabetta Bugianesi, Jörn M. Schattenberg, Ann K. Daly, Tuulia Hyötyläinen, Quentin M. Anstee, Matej Orešič
Publikováno v:
JHEP Reports
Funder: European Commission
BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) is a progressive liver disease with potentially severe complications including cirrhosis and hepatocellular carcinoma. Previously, we have identified circul
BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) is a progressive liver disease with potentially severe complications including cirrhosis and hepatocellular carcinoma. Previously, we have identified circul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dccc15694575d45eb24a234f95e9680
https://pubmed.ncbi.nlm.nih.gov/35434590
https://pubmed.ncbi.nlm.nih.gov/35434590
Autor:
Caroline Richard, Jean Buteau, John P. Kennelly, Tingting Ju, Stephanie Carlin, Ben P. Willing, Jelske N. van der Veen, Aducio Thiesen, René L. Jacobs, Randal Nelson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 999-1021 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Patients with ulcerative colitis have low concentrations of the major membrane lipid phosphatidylcholine (PC) in gastrointestinal mucus, suggesting that defects in colonic PC metabolism might be involved in the development of coliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cb572fe2a00cfe78b75990b8fc2494
http://www.sciencedirect.com/science/article/pii/S2352345X20301855
http://www.sciencedirect.com/science/article/pii/S2352345X20301855
Autor:
Zhonghua Wang, Zeper Abliz, Meiling Huo, Chunyan Yang, Bingshu He, Wenqing Fu, Yaqi Liu, Jinfeng Wei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 6, Pp 1083-1093 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development. Herein, an in situ metabolomics method based on air flow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI) wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e79605efb06e65af3a2ee9300ab4fcf
http://www.sciencedirect.com/science/article/pii/S2211383519310718
http://www.sciencedirect.com/science/article/pii/S2211383519310718