Zobrazeno 1 - 10
of 171
pro vyhledávání: '"PBMCS, peripheral blood mononuclear cells"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Most transcriptomic studies of SARS-CoV-2 infection have focused on differentially expressed genes, which do not necessarily reveal the genes mediating the transcriptomic changes. In contrast, exploiting curated biological network, our PathExt tool i
Externí odkaz:
https://doaj.org/article/a4dcfde205cd496da9aa054e8034ae34
Akademický článek
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Autor:
Flora Reverchon, Colleen Guillard, Lucile Mollet, Pascal Auzou, David Gosset, Fahima Madouri, Antoine Valéry, Arnaud Menuet, Canan Ozsancak, Maud Pallix-Guyot, Séverine Morisset-Lopez
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2418 (2022)
Serotonin (5-HT) is known as a potent immune cell modulator in autoimmune diseases and should be protective in the pathogenesis of multiple sclerosis (MS). Nevertheless, there is limited knowledge about receptors involved in 5-HT effects as well as i
Externí odkaz:
https://doaj.org/article/68bf6b51562648c983b0ebc0d825ecc5
Autor:
Sanaa Sharari, Basirudeen Kabeer, Idris Mohammed, Basma Haris, Igor Pavlovski, Iman Hawari, Ajaz Ahmad Bhat, Mohammed Toufiq, Sara Tomei, Rebecca Mathew, Najeeb Syed, Sabah Nisar, Selma Maacha, Jean-Charles Grivel, Damien Chaussabel, Johan Ericsson, Khalid Hussain
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2114 (2022)
Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized by the accumulation of glycogen mainly in the liver. It is inherited in an autosomal recessive manner due to mutations in the SLC2A2 gene. SLC2A2 enco
Externí odkaz:
https://doaj.org/article/fdc507a460194407a6173afa34a196b8
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
In biology, models are experimental systems meant to recreate aspects of diseases or human tissue with the goal of generating inferences and approximations that can contribute to the resolution of specific biological problems. Although there are many
Externí odkaz:
https://doaj.org/article/32c21e560f994517a630a6c2a8e263bb
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6653-6673 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6653-6673 (2021)
Graphical abstract
Several plants have traditionally been used since antiquity to treat various gastroenteritis and respiratory symptoms similar to COVID-19 outcomes. The common symptoms of COVID-19 include fever or chills, cold, cough, flu, hea
Several plants have traditionally been used since antiquity to treat various gastroenteritis and respiratory symptoms similar to COVID-19 outcomes. The common symptoms of COVID-19 include fever or chills, cold, cough, flu, hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb3987308abcc1d8a8d204193a54c90
https://doi.org/10.1016/j.sjbs.2021.07.036
https://doi.org/10.1016/j.sjbs.2021.07.036
Autor:
Po Hu, Hongzheng Wang, Xiaoxuan Yu, Wenzhuo Sun, Hui Hui, Hui Li, Mengyuan Zhu, Zhanyu Wang, Jingyan Xu, Qinglong Guo, Yingjie Qing
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3178-3192 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The integrity of lysosomes is of vital importance to survival of tumor cells. We demonstrated that LW-218, a synthetic flavonoid, induced rapid lysosomal enlargement accompanied with lysosomal membrane permeabilization in hematological malignancy. LW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2bc1bb062d92dcf545995a174a1320
http://www.sciencedirect.com/science/article/pii/S2211383521000411
http://www.sciencedirect.com/science/article/pii/S2211383521000411
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 976-988 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 976-988 (2021)
Graphical abstract
Chemokines are crucial inflammatory mediators needed during an immune response to clear pathogens. However, their excessive release is the main cause of hyperinflammation. In the recent COVID-19 outbreak, chemokines may be the
Chemokines are crucial inflammatory mediators needed during an immune response to clear pathogens. However, their excessive release is the main cause of hyperinflammation. In the recent COVID-19 outbreak, chemokines may be the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a813633e01cb0494554b46fedd72c61
http://europepmc.org/articles/PMC7859556
http://europepmc.org/articles/PMC7859556
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2272-2298 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Multiple cancer immunotherapies including chimeric antigen receptor T cell and immune checkpoint inhibitors (ICIs) have been successfully developed to treat various cancers by motivating the adaptive anti-tumor immunity. Particularly, the checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c604607610f05b2d37da5b2cce00382
http://www.sciencedirect.com/science/article/pii/S2211383519316946
http://www.sciencedirect.com/science/article/pii/S2211383519316946
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2962-2971 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2962-2971 (2020)
The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcea929efae2a79c6e83f039420cd4a
https://doi.org/10.1016/j.csbj.2020.10.016
https://doi.org/10.1016/j.csbj.2020.10.016