Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5.

Autor: Zhang X; Beijing Institute of Basic Medical Sciences, Beijing, China., Ma C; Beijing Institute of Basic Medical Sciences, Beijing, China., Lu Y; Beijing Institute of Basic Medical Sciences, Beijing, China., Wang J; Beijing Institute of Basic Medical Sciences, Beijing, China., Yun H; Beijing Institute of Basic Medical Sciences, Beijing, China., Jiang H; Beijing Institute of Basic Medical Sciences, Beijing, China.; University of South China, Hengyang Medical School, Hengyang, China., Wu M; Beijing Institute of Basic Medical Sciences, Beijing, China.; Anhui Medical University, Hefei, China., Feng X; Beijing Institute of Basic Medical Sciences, Beijing, China.; Henan University Joint National Laboratory for Antibody Drug Engineering, Kaifeng, China., Gai W; Beijing Institute of Basic Medical Sciences, Beijing, China., Xu G; Beijing Institute of Basic Medical Sciences, Beijing, China., Deng H; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Feng J; Henan University Joint National Laboratory for Antibody Drug Engineering, Kaifeng, China.; National Engineering Research Center for Emergence Drugs, Beijing Institute of Pharmacology and Toxicology, Beijing, China., Liu W; Institute of Life Sciences, Tsinghua University, Beijing, China., Shi T; Beijing Institute of Basic Medical Sciences, Beijing, China. shitaoxing@sina.com., Cheng Q; Beijing Institute of Basic Medical Sciences, Beijing, China. chengqianqian044271@126.com., Zhang J; Beijing Institute of Basic Medical Sciences, Beijing, China. zhangjy@bmi.ac.cn.; University of South China, Hengyang Medical School, Hengyang, China. zhangjy@bmi.ac.cn.; Anhui Medical University, Hefei, China. zhangjy@bmi.ac.cn.; Henan University Joint National Laboratory for Antibody Drug Engineering, Kaifeng, China. zhangjy@bmi.ac.cn.; Chinese Institute for Brain Research, Beijing, China. zhangjy@bmi.ac.cn.

Publikováno v: Cellular & molecular immunology [Cell Mol Immunol] 2024 Nov; Vol. 21 (11), pp. 1282-1295. Date of Electronic Publication: 2024 Sep 10.

PAX5 and CD70 are expressed in thymic carcinoma but not in atypical thymoma (WHO type B3 thymoma): an immunohistochemical analysis of 60 cases.

Autor: Weissferdt A; Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA aweissferdt@mdanderson.org., Moran C; Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Publikováno v: Journal of clinical pathology [J Clin Pathol] 2024 Oct 20; Vol. 77 (11), pp. 761-765. Date of Electronic Publication: 2024 Oct 20.

The transcription factor PAX5 activates human LINE1 retrotransposons to induce cellular senescence.

Autor: Tang H; Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China., Yang J; Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China., Xu J; Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China., Zhang W; Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China., Geng A; Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China., Jiang Y; Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China., Mao Z; Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. zhiyong_mao@tongji.edu.cn.; School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. zhiyong_mao@tongji.edu.cn.

Publikováno v: EMBO reports [EMBO Rep] 2024 Aug; Vol. 25 (8), pp. 3263-3275. Date of Electronic Publication: 2024 Jun 12.

Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers.

Autor: Bhattacharya S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Harris HL; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA., Islam R; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Bodas S; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA., Polavaram N; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Mishra J; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USA., Das D; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Seshacharyulu P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Kalluchi A; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA., Pal A; Data Scientist, Gallup, Omaha, NE, USA., Kohli M; School of Medicine, Division of Oncology, Huntsman Cancer Institute, Salt Lake City, UT, USA., Lele SM; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Muders M; MVZ Pathology Bethesda, Heerstrasse 219, Duisburg, Germany., Batra SK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Ghosh PM; Department of Urological Surgery, University of California Davis, School of Medicine, Sacramento, CA, USA., Datta K; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USA., Rowley MJ; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA. jordan.rowley@unmc.edu., Dutta S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA. samikshan.dutta@vcuhealth.edu.; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USA. samikshan.dutta@vcuhealth.edu.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 Aug 25; Vol. 15 (8), pp. 617. Date of Electronic Publication: 2024 Aug 25.

Identification and clinical implications of recurrent PAX5::MLLT3 fusion in lymphoid blastic phase chronic myeloid leukemia.

Autor: Wang L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China., Chen Y; Department of Hematology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, China., Wang Q; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China., Xiang M; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China., Zeng Z; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China., Zhang Z; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China., Zhang F; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China., Chen S; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China., Xue M; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Publikováno v: International journal of laboratory hematology [Int J Lab Hematol] 2024 Jun; Vol. 46 (3), pp. 571-574. Date of Electronic Publication: 2024 Feb 23.