Zobrazeno 1 - 10
of 368
pro vyhledávání: '"PAX1"'
Autor:
Xiaoyan Chen, Haimin Jiang, Hubin Xu, Linhai Wang, Pei Liu, Dongxue Ma, Hui Wang, Huafeng Shou, Xuqian Fang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Atypical squamous cells of undetermined significance (ASC-US) often present diagnostic challenges with cytology-based results, leading to potential underdiagnosis or overdiagnosis. An effective triage method is essential for manag
Externí odkaz:
https://doaj.org/article/1b2c78e051ab4ec2957a6b9083e0ea4f
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Primary screening for high-risk human papillomavirus (hrHPV) with cytological triage for women with non-16/18 hrHPV-positive status has become popular in China. However, cytology relies on the subjective judgment of pathologists,
Externí odkaz:
https://doaj.org/article/9b1d51a883034c7ab1e506309155e762
Autor:
Haijun Luo, Yixiang Lian, Hong Tao, Yan Zhao, Zhigan Wang, Jing Zhou, Zirong Zhang, Shali Jiang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The risk of cervical cancer progression in high-risk human papillomavirus (HR-HPV)-positive women is associated with cervical lesion severity and molecular heterogeneity. Classification systems based on p16 and Ki67 expression cum
Externí odkaz:
https://doaj.org/article/fe0b53ef890c479781dd988645188b02
Publikováno v:
Zhongguo aizheng zazhi, Vol 34, Iss 8, Pp 734-744 (2024)
Background and purpose: At present, there have been many reports on the study of methylation in cervical lesions, however it is still not clinically practical as a diagnostic and shunting index of cervical lesions. In this study, we intended to inves
Externí odkaz:
https://doaj.org/article/4ca0b8528ca142d588d1058d507df4b8
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background In China, the national cervical cancer screening protocol involves initial testing for high-risk human papillomavirus (hrHPV), followed by cytology for hrHPV-positive cases. This study evaluates the effectiveness of PAX1 methylati
Externí odkaz:
https://doaj.org/article/bf890b9835e84ffa96040d692867d357
Autor:
Yingnan Lu, Haiyue Wu, Kun Fu, YuFei Shen, Lucia Li, Zexi Liao, Yingzhen Liu, Yanan Kang, Yu Zhang
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Objective The major challenge in routine endocervical curettage (ECC) among Human Papillomavirus (HPV) 16/18-positive patients is that only a small fraction benefit. Nevertheless, current reported models often overestimate the validity and n
Externí odkaz:
https://doaj.org/article/da2d6443e895442d9d2dcb169dc43711
Akademický článek
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Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Paired box 1 (PAX1) is a transcription factor and essential for the development of pharyngeal pouches-derived tissues, including thymus. PAX1 mutations are identified in Severe Combined Immunodeficiency (SCID) patients with Otofac
Externí odkaz:
https://doaj.org/article/48a94726aadc40899b5c41c68f91c98e
Publikováno v:
陆军军医大学学报, Vol 46, Iss 4, Pp 390-395 (2024)
Objective To compare paired boxed gene 1(PAX1) methylation and p16/Ki-67 double staining alone and in combination in thinprep cytologic test (TCT) for distinguishing atypical squamous cells of undetermined significance (ASC-US) and low-grade squamous
Externí odkaz:
https://doaj.org/article/33f7ae61135f4b6abdc9659735bcfb69
Autor:
Xuanxuan Li, Huan Liu, Xue Zhou, Yangying Zhou, Yu Zhang, Yu-Ligh Liou, Manting Zeng, Hong Zhu
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background PAX1 gene methylation plays an important role in the development of cervical cancer. However, its prognostic value after radiotherapy for locally advanced cervical cancer is unknown, so this study aimed to investigate the value of
Externí odkaz:
https://doaj.org/article/df9edb72fb0c4e90bba81b226de8ecb2