Zobrazeno 1 - 10
of 123
pro vyhledávání: '"PAVEL DOLEŽAL"'
Autor:
Vít Dohnálek, Pavel Doležal
Publikováno v:
Open Biology, Vol 14, Iss 5 (2024)
Core mitochondrial processes such as the electron transport chain, protein translation and the formation of Fe–S clusters (ISC) are of prokaryotic origin and were present in the bacterial ancestor of mitochondria. In animal and fungal models, a fam
Externí odkaz:
https://doaj.org/article/80fcfe70e0c5488f93f4c74770b2f1a0
Autor:
Marcela Martončíková, Pavel Doležal, Kamila Fabianová, Miloslav Karhánek, Ján Gálik, Adam Raček, Alexandra Popovičová, Enikő Račeková
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Olfactory dysfunction associated with coronavirus 2 (SARS-CoV-2) infection is in most cases transient, recovering spontaneously within a few days. However, in some patients it persists for a long time, affects their everyday life and endange
Externí odkaz:
https://doaj.org/article/d4de03fb838544219637062690014149
Autor:
Alžběta Motyčková, Luboš Voleman, Vladimíra Najdrová, Lenka Arbonová, Martin Benda, Vít Dohnálek, Natalia Janowicz, Ronald Malych, Róbert Šuťák, Thijs J G Ettema, Staffan Svärd, Courtney W Stairs, Pavel Doležal
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1010773 (2023)
Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters, which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway mediates the formation of these clusters from simpler [2Fe-2S] mo
Externí odkaz:
https://doaj.org/article/16b4df0815e745b29687962ec20e8cbb
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Over the billions of years that bacteria have been around, they have evolved several sophisticated protein secretion nanomachines to deliver toxins, hydrolytic enzymes, and effector proteins into their environments. Of these, the type II sec
Externí odkaz:
https://doaj.org/article/34ce86bd2b764221b2b689738a9fcc4e
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background The presence of mitochondria is a distinguishing feature between prokaryotic and eukaryotic cells. It is currently accepted that the evolutionary origin of mitochondria coincided with the formation of eukaryotes and from that poin
Externí odkaz:
https://doaj.org/article/b6b8d75ab9d745c98626bd663dd17d84
Autor:
Lenka Horváthová, Vojtěch Žárský, Tomáš Pánek, Romain Derelle, Jan Pyrih, Alžběta Motyčková, Veronika Klápšťová, Martina Vinopalová, Lenka Marková, Luboš Voleman, Vladimír Klimeš, Markéta Petrů, Zuzana Vaitová, Ivan Čepička, Klára Hryzáková, Karel Harant, Michael W. Gray, Mohamed Chami, Ingrid Guilvout, Olivera Francetic, B. Franz Lang, Čestmír Vlček, Anastasios D. Tsaousis, Marek Eliáš, Pavel Doležal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Bacteria use the type 2 secretion system to secrete enzymes and toxins across the outer membrane to the environment. Here the authors analyse the T2SS pathway in three protist lineages and suggest that the early mitochondrion may have been capable of
Externí odkaz:
https://doaj.org/article/994e70e482df4d9db87d65239e08f13f
Autor:
Vendula Horáčková, Luboš Voleman, Kari D. Hagen, Markéta Petrů, Martina Vinopalová, Filip Weisz, Natalia Janowicz, Lenka Marková, Alžběta Motyčková, Vladimíra Najdrová, Pavla Tůmová, Scott C. Dawson, Pavel Doležal
Publikováno v:
Open Biology, Vol 12, Iss 4 (2022)
CRISPR/Cas9-mediated genome editing has become an extremely powerful technique used to modify gene expression in many organisms, including parasitic protists. Giardia intestinalis, a protist parasite that infects approximately 280 million people arou
Externí odkaz:
https://doaj.org/article/d96837c111014c348aaa6b61ad7d506b
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background Eukaryotic gene expression is controlled by a number of RNA-binding proteins (RBP), such as the proteins from the Puf (Pumilio and FBF) superfamily (PufSF). These proteins bind to RNA via multiple Puf repeat domains, each of which
Externí odkaz:
https://doaj.org/article/80815e0b57604269a19edd3a4f78a028
Autor:
Markéta Petrů, Jeremy Wideman, Kristoffer Moore, Felicity Alcock, Tracy Palmer, Pavel Doležal
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background Bacteria and mitochondria contain translocases that function to transport proteins across or insert proteins into their inner and outer membranes. Extant mitochondria retain some bacterial-derived translocases but have lost others
Externí odkaz:
https://doaj.org/article/7af58414a58d491cafb3e90638208da1
Autor:
Luboš Voleman, Pavel Doležal
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1008008 (2019)
The shape and number of mitochondria respond to the metabolic needs during the cell cycle of the eukaryotic cell. In the best-studied model systems of animals and fungi, the cells contain many mitochondria, each carrying its own nucleoid. The organel
Externí odkaz:
https://doaj.org/article/ead236f023fc445fb40a8e8afabf8659