Zobrazeno 1 - 10
of 217
pro vyhledávání: '"PAULO A.S. MOURÃO"'
Autor:
BIANCA B. COSTA, JESSICA L.D. GIANELLI, THAMYRIS A. MOREIRA, ANGELICA R. SOARES, BIANCA F. GLAUSER, PAULO A.S. MOURÃO, CHAQUIP D. NETO, CINTHIA M. BARROS, LEONARDO P. CINELLI
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 95, Iss 2 (2023)
Abstract The number of deaths associated with cardiovascular diseases (CVD) increases every year, leading to an intense search for new compounds that may be employed as anticoagulants. One of the classes of bioprospected molecules comprises sulfated
Externí odkaz:
https://doaj.org/article/bcacb1690fe34b73a7c0fc6e10bff059
Autor:
Stephan N.M.C.G. Oliveira, Ana M.F. Tovar, Francisco F. Bezerra, Adriana A. Piquet, Nina V. Capillé, Paloma S. Santos, Eduardo Vilanova, Paulo A.S. Mourão
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e309-e322 (2022)
Heparin has already been found in a variety of animal tissues but only few of them became effective sources for production of pharmaceutical preparations. Here, we correlate physical-chemical features and anticoagulant activities of structurally simi
Externí odkaz:
https://doaj.org/article/2e7a794c0a5b4812b45bf16ff6289cae
Autor:
Roberto P. Santos, Ana M.F. Tovar, Marcos R. Oliveira, Adriana A. Piquet, Nina V. Capillé, Stephan N.M.C.G. Oliveira, Ana H. Correia, José N. Farias, Eduardo Vilanova, Paulo A.S. Mourão
Publikováno v:
TH Open, Vol 06, Iss 02, Pp e114-e123 (2022)
Heparin is a centennial anticoagulant drug broadly employed for treatment and prophylaxis of thromboembolic conditions. Although unfractionated heparin (UFH) has already been shown to have remarkable pharmacological potential for treating a variety o
Externí odkaz:
https://doaj.org/article/f43f4cd91e9b4cfa8e41de4419042cd5
Autor:
Francisco Felipe Bezerra, Stephan N.M.C.G. Oliveira, Rodrigo A. Sales, Adriana A. Piquet, Nina V. Capillé, Eduardo Vilanova, Ana M.F. Tovar, Paulo A.S. Mourão
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1115 (2023)
Pharmaceutical heparins from different manufacturers may present heterogeneities due to particular extraction and purification procedures or even variations in the raw material manipulation. Heparins obtained from different tissues also differ in the
Externí odkaz:
https://doaj.org/article/5162564403cd4d2d9c320a111ed9e50d
Autor:
Gabrielle M. Valle, Leonardo P. Cinelli, Adriane R. Todeschini, Lycia de Brito-Gitirana, Ana-Cristina E.S. Vilela-Silva, Paulo A.S. Mourão
Publikováno v:
Brazilian Archives of Biology and Technology, Vol 58, Iss 4, Pp 617-627 (2015)
This work found the occurrence of a distinct sialic acid-rich polysaccharide in the sperm surface of the sea urchin Lytechinus variegatus, which differed significantly from a similar molecule found in the egg jelly. The sperm polysaccharide extracted
Externí odkaz:
https://doaj.org/article/bd666994f6304989a0ea928c7d9f89c9
Publikováno v:
Arquivos Brasileiros de Cardiologia, Vol 98, Iss 1, Pp e11-e14 (2012)
Algumas patentes das heparinas de baixo peso molecular expiraram e outras estão vencendo. Versões biossimilares desses fármacos estão disponíveis para o uso clínico em vários países. Entretanto, ainda persiste ceticismo sobre a possibilidade
Externí odkaz:
https://doaj.org/article/a40ee5eaf6bd4521bb6d329fa346feea
Autor:
Ana Maria Sampaio Assreuy, Francisco F. Bezerra, Paulo A.S. Mourão, Arcelina Pacheco Cunha, Maria Gonçalves Pereira, Diego Freitas de Araujo, Nágila M.P.S. Ricardo, Juliana C. Madeira
Publikováno v:
International Journal of Biological Macromolecules. 175:147-155
This study aimed to isolate, characterize chemical-structurally and evaluate the effects of polysaccharides from Caesalpinia (Libidibia) ferrea stem barks in the haemostatic system. The deproteinated-polysaccharide extract (PE-Cf) after being fractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299bb9639f9027a4bfa64454b50d393a
https://doi.org/10.1016/j.ijbiomac.2021.01.177
https://doi.org/10.1016/j.ijbiomac.2021.01.177
Autor:
Nidyedja Goyanna Gomes Gonçalves, Huai N. Cheng, Alexandre Magno Rodrigues Teixeira, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro-Moreira, Fernanda N. Rodrigues, A. C. H. Barreto, Paulo A.S. Mourão, Francisco Rogênio da Silva Mendes, Kelvi Wilson Evaristo Miranda, Francisco F. Bezerra, Hélcio Silva dos Santos, Maria do Socorro Rocha Bastos, Atanu Biswas, Mateus T. Aerre
Iron nanoparticles (FeNP) present excellent magnetic properties and chemical stability, and for this reason, they are often configured into materials for a variety of potential uses in medical, biotechnological, and other applications. In this work,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7642d57c9a509135f84a7f978ca02d4c
https://doi.org/10.3762/bxiv.2021.67.v1
https://doi.org/10.3762/bxiv.2021.67.v1
Publikováno v:
Marine Drugs, Vol 19, Iss 425, p 425 (2021)
Marine Drugs
Marine Drugs
Marine organisms are a source of active biomolecules with immense therapeutic and nutraceutical potential. Sulfated fucose-rich polysaccharides are present in large quantities in these organisms with important pharmacological effects in several biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7158fadbb2bf51a6002863143d4a58f
https://www.mdpi.com/1660-3397/19/8/425
https://www.mdpi.com/1660-3397/19/8/425
Autor:
Caroline Nogueira Faria, Leonardo Paes Cinelli, Regina Célia Alves Celestino, Paulo A.S. Mourão, Bianca F. Glauser, Gustavo R.C. Santos, Jéssica Lopes D.Dego Gianelli, Carlos Rangel Rodrigues, Angélica Ribeiro Soares, Thamyris Almeida Moreira, Bianca Barros da Costa
Publikováno v:
Ciência Rural, Vol 51, Iss 8 (2021)
Ciência Rural v.51 n.8 2021
Ciência Rural
Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
Ciência Rural, Volume: 51, Issue: 8, Article number: e20200138, Published: 02 JUN 2021
Ciência Rural v.51 n.8 2021
Ciência Rural
Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
Ciência Rural, Volume: 51, Issue: 8, Article number: e20200138, Published: 02 JUN 2021
Marine algae are natural sources of macromolecules known as sulfated polysaccharides. This class of compounds has attracted the interest of Pharmaceutical Sciences due to its pharmacological anticoagulant, antiplatelet and antithrombotic properties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106c84ea63ad245668a89018345185ec
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782021000800604&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782021000800604&tlng=en