Zobrazeno 1 - 10
of 57
pro vyhledávání: '"PAUL H. AYRES"'
Autor:
Ryan J. Potts, Paul H. Ayres, Paul R. Harp, Steven J. Kathman, Cody L. Wilson, Charles D. Garner
Publikováno v:
Regulatory Toxicology and Pharmacology. 58:106-113
The mouse dermal assay has long been used to assess the dermal tumorigenicity of cigarette smoke condensate (CSC). This mouse skin model has been developed for use in carcinogenicity testing utilizing the SENCAR mouse as the standard strain. Though t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84a91429f374df81f286314957bf96f
https://doi.org/10.1016/j.yrtph.2010.04.010
https://doi.org/10.1016/j.yrtph.2010.04.010
Publikováno v:
Experimental and Toxicologic Pathology. 62:117-126
A tiered testing strategy based on a comparative chemical and biological testing program has been developed to evaluate the potential of tobacco processes, ingredients, or other technological developments to change the biological activity that result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00918282c7d08ad4d161297dbbb9688
https://doi.org/10.1016/j.etp.2009.02.121
https://doi.org/10.1016/j.etp.2009.02.121
Autor:
Betsy Bombick, W. Keith Shreve, Paul H. Ayres, Michael F. Borgerding, Eugenia H. Theophilus, Charles D. Garner, Deborah H. Pence, James E. Swauger, Daniel R. Meckley
Publikováno v:
Experimental and Toxicologic Pathology. 59:17-27
A tiered testing strategy has been employed to evaluate the potential of tobacco processes, ingredients, or technological developments to change the biological activity resulting from burning cigarette tobacco. The strategy is based on comparative ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e41a9cc2325946453f223f6867fbe37
https://doi.org/10.1016/j.etp.2007.02.006
https://doi.org/10.1016/j.etp.2007.02.006
Autor:
Johnnie R. Hayes, Allen Singer, Dawn Fallacara, Paul H. Ayres, Eugenia H. Theophilus, Milton R. Hejtmancik, Charles D. Garner, Ryan J. Potts, Walter T. Morgan
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 67(10)
A comprehensive 2-year oral chronic toxicity/carcinogenicity study was conducted with smokeless tobacco using modern toxicological test methods and well-accepted standards. The study included a 1-year interim subgroup to assess toxicity at that inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132fcf589396b89fe33ada797c02578e
https://pubmed.ncbi.nlm.nih.gov/26382975
https://pubmed.ncbi.nlm.nih.gov/26382975
Autor:
James E. Swauger, Mari S. Stavanja, Deborah H. Pence, Michael F. Borgerding, Paul H. Ayres, Elizabeth R. Bombick, Daniel R. Meckley, Charles D. Garner, Michael J. Morton
Publikováno v:
Experimental and Toxicologic Pathology. 57:267-281
A tiered testing strategy has been developed to evaluate the potential for new ingredients, tobacco processes, and technological developments to alter the biological activity that results from burning tobacco. A series of studies was initially conduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea2cb86ab397e0f0ca8d063ec189ff7
https://doi.org/10.1016/j.etp.2005.10.003
https://doi.org/10.1016/j.etp.2005.10.003
Autor:
Johnnie R. Hayes, Arnold T. Mosberg, Daniel R. Meckley, K.R. Van Kampen, Paul H. Ayres, James E. Swauger
Publikováno v:
Food and Chemical Toxicology. 42:851-863
Numerous chemical and toxicological studies indicate that smoke from ECLIPSE, a cigarette that primarily heats rather than burns tobacco, is simplified and reduced in specific chemicals believed to be associated with smoking-related diseases, and dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fb74c2a6e888ec4cad6ea11e1142ab
https://doi.org/10.1016/j.fct.2004.01.009
https://doi.org/10.1016/j.fct.2004.01.009
Autor:
Deborah H. Pence, Eugenia H. Theophilus, Mark A. Higuchi, Betsy Bombick, James E. Swauger, Daniel R. Meckley, Paul H. Ayres, Michael F. Borgerding
Publikováno v:
Food and Chemical Toxicology. 42:631-639
A tiered testing strategy has been developed to evaluate the potential of tobacco processes, ingredients, or technological developments to change the biological activity resulting from burning tobacco. The strategy is based on comparative chemical an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e52938897bbd4a2ba60b9647a732b7f
https://doi.org/10.1016/j.fct.2003.11.008
https://doi.org/10.1016/j.fct.2003.11.008
Publikováno v:
Inhalation Toxicology. 16:1-20
A subchronic, nose-only inhalation study compared the effects of mainstream smoke from a 1R4F research cigarette to that of a 2R4F research cigarette. Male and female rats were exposed for 1 h/day, 5 days/wk, for 13 wk to mainstream smoke at 0, 0.06,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c7564f65434c61226b11f6ab257f50
https://doi.org/10.1080/08958370490271340
https://doi.org/10.1080/08958370490271340
Autor:
Mari S. Stavanja, Arnold T. Mosberg, James E. Swauger, Daniel R. Meckley, Betsy Bombick, Michael F. Borgerding, Deborah H. Pence, Michael J. Morton, Paul H. Ayres
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 66:1453-1474
A tiered testing strategy has been developed to evaluate the potential for new ingredients, tobacco processes, and technological developments to increase or reduce the biological activity that results from burning tobacco. In the manufacture of cigar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f538000d34ec796724b632a62ee90c
https://doi.org/10.1080/15287390306413
https://doi.org/10.1080/15287390306413
Autor:
W. Keith Shreve, Arnold T. Mosberg, Steven Kinsler, Deborah H. Pence, John W. Sagartz, Paul H. Ayres
Publikováno v:
Inhalation Toxicology. 15:819-854
A subchronic, nose-only inhalation study compared the effects of mainstream smoke from a cigarette containing 100% flue-cured tobacco cured by a direct-fired process to that of a cigarette containing 100% flue-cured tobacco cured by a heat exchanger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8310d5d905bf3324bfe6e08ee7c58398
https://doi.org/10.1080/08958370390217864
https://doi.org/10.1080/08958370390217864