A protocol for the formative evaluation of the implementation of patient-reported outcome measures in child and adolescent mental health services as part of a learning health system

Autor: Erin McCabe, Michele Dyson, Deborah McNeil, Whitney Hindmarch, Iliana Ortega, Paul D. Arnold, Gina Dimitropoulos, Ryan Clements, Maria J. Santana, Jennifer D. Zwicker

Publikováno v: Health Research Policy and Systems, Vol 22, Iss 1, Pp 1-10 (2024)

Abstract Background Mental health conditions affect one in seven young people and research suggests that current mental health services are not meeting the needs of most children and youth. Learning health systems are an approach to enhancing service

Externí odkaz: https://doaj.org/article/f87f1f0efb4741f2901207cf78d566cd

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals

Autor: Nora I. Strom, Dirk J. A. Smit, Talisa Silzer, Conrad Iyegbe, Christie L. Burton, René Pool, Mathieu Lemire, James J. Crowley, Jouke-Jan Hottenga, Volen Z. Ivanov, Henrik Larsson, Paul Lichtenstein, Patrik Magnusson, Christian Rück, Russell J. Schachar, Hei Man Wu, Sandra M. Meier, Jennifer Crosbie, Paul D. Arnold, Manuel Mattheisen, Dorret I. Boomsma, David Mataix-Cols, Danielle Cath

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)

Abstract Hoarding Disorder (HD) is a mental disorder characterized by persistent difficulties discarding or parting with possessions, often resulting in cluttered living spaces, distress, and impairment. Its etiology is largely unknown, but twin stud

Externí odkaz: https://doaj.org/article/2799ba1feac14143b49c5a113c6f2e18

The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder

Autor: Cees J. Weeland, Selina Kasprzak, Niels T. de Joode, Yoshinari Abe, Pino Alonso, Stephanie H. Ameis, Alan Anticevic, Paul D. Arnold, Srinivas Balachander, Nerisa Banaj, Nuria Bargallo, Marcelo C. Batistuzzo, Francesco Benedetti, Jan C. Beucke, Irene Bollettini, Vilde Brecke, Silvia Brem, Carolina Cappi, Yuqi Cheng, Kang Ik K. Cho, Daniel L. C. Costa, Sara Dallaspezia, Damiaan Denys, Goi Khia Eng, Sónia Ferreira, Jamie D. Feusner, Martine Fontaine, Jean-Paul Fouche, Rachael G. Grazioplene, Patricia Gruner, Mengxin He, Yoshiyuki Hirano, Marcelo Q. Hoexter, Chaim Huyser, Hao Hu, Fern Jaspers-Fayer, Norbert Kathmann, Christian Kaufmann, Minah Kim, Kathrin Koch, Yoo Bin Kwak, Jun Soo Kwon, Luisa Lazaro, Chiang-shan R. Li, Christine Lochner, Rachel Marsh, Ignacio Martínez-Zalacaín, David Mataix-Cols, Jose M. Menchón, Luciano Minnuzi, Pedro Silva Moreira, Pedro Morgado, Akiko Nakagawa, Takashi Nakamae, Janardhanan C. Narayanaswamy, Erika L. Nurmi, Ana E. Ortiz, Jose C. Pariente, John Piacentini, Maria Picó-Pérez, Fabrizio Piras, Federica Piras, Christopher Pittenger, Y. C. Janardhan Reddy, Daniela Rodriguez-Manrique, Yuki Sakai, Eiji Shimizu, Venkataram Shivakumar, Helen Blair Simpson, Noam Soreni, Carles Soriano-Mas, Nuno Sousa, Gianfranco Spalletta, Emily R. Stern, Michael C. Stevens, S. Evelyn Stewart, Philip R. Szeszko, Jumpei Takahashi, Tais Tanamatis, Jinsong Tang, Anders Lillevik Thorsen, David Tolin, Ysbrand D. van der Werf, Hein van Marle, Guido A. van Wingen, Daniela Vecchio, G. Venkatasubramanian, Susanne Walitza, Jicai Wang, Zhen Wang, Anri Watanabe, Lidewij H. Wolters, Xiufeng Xu, Je-Yeon Yun, Qing Zhao, ENIGMA OCD Working Group, Tonya White, Paul M. Thompson, Dan J. Stein, Odile A. van den Heuvel, Chris Vriend

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract Larger thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population. Particular thalamic subregions may drive these differences. The ENIGMA-OCD wo

Externí odkaz: https://doaj.org/article/bb65486e4fcd4be1bdc3f13601d6f34a

Hyperfocus or flow? Attentional strengths in autism spectrum disorder

Autor: Annie Dupuis, Piyumi Mudiyanselage, Christie L. Burton, Paul D. Arnold, Jennifer Crosbie, Russell J. Schachar

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

The comorbidity of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) diagnoses is well established. An ASD diagnosis is associated with elevated ADHD traits and symptoms, as well as strengths in attention. In the ASD

Externí odkaz: https://doaj.org/article/b45886b3be744d9fbb103e0509ac3057

Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation

Autor: Sarah J. Goodman, Christie L. Burton, Darci T. Butcher, Michelle T. Siu, Mathieu Lemire, Eric Chater-Diehl, Andrei L. Turinsky, Michael Brudno, Noam Soreni, David Rosenberg, Kate D. Fitzgerald, Gregory L. Hanna, Evdokia Anagnostou, Paul D. Arnold, Jennifer Crosbie, Russell Schachar, Rosanna Weksberg

Publikováno v: Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-15 (2020)

Abstract Background A growing body of research has demonstrated associations between specific neurodevelopmental disorders and variation in DNA methylation (DNAm), implicating this molecular mark as a possible contributor to the molecular etiology of

Externí odkaz: https://doaj.org/article/e2c63c023729431c9951220028dadec0