Zobrazeno 1 - 10
of 141
pro vyhledávání: '"PATRICIA MENDONCA"'
Publikováno v:
Nutrients, Vol 16, Iss 15, p 2392 (2024)
Breast cancer is the second-leading cause of cancer death among women in the United States. Triple-negative breast cancer (TNBC), a subtype of breast cancer, is an aggressive phenotype that lacks estrogen (ER), progesterone (PR), and human epidermal
Externí odkaz:
https://doaj.org/article/4ac262477d5244fa9b989894d92e74cc
Autor:
Shade’ A. Ahmed, Patricia Mendonca, Samia S. Messeha, Ebenezer T. Oriaku, Karam F. A. Soliman
Publikováno v:
Molecules, Vol 29, Iss 1, p 61 (2023)
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks specific targets such as estrogen, progesterone, and HER2 receptors. TNBC affects one in eight women in the United States, making up 15–20% of breast cancer c
Externí odkaz:
https://doaj.org/article/773aaf4063284493bfb679990032b95f
Publikováno v:
Molecules, Vol 28, Iss 18, p 6536 (2023)
The absence of progesterone receptors, estrogen receptors, and human epidermal growth factor receptor-2 restricts the therapy choices for treating triple-negative breast cancer (TNBC). Moreover, conventional medication is not highly effective in trea
Externí odkaz:
https://doaj.org/article/45e2b8d6d55e4bf9b5777dbb90956465
Publikováno v:
Brain Sciences, Vol 13, Iss 8, p 1144 (2023)
Alzheimer’s disease is a progressive neurodegenerative disorder leading to cognitive decline and memory loss. The incidence of this disease continues to increase due to the limited number of novel therapeutics that prevent or slow down its progress
Externí odkaz:
https://doaj.org/article/cd6da53aa4d84cd88fc362b3c8bef3a4
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10872 (2023)
Chronic oxidative stress (OS) and inflammation are implicated in developing and progressing neurodegenerative diseases (NDs). The chronic activation of microglia cells leads to the overproduction of several substances, including nitric oxide and reac
Externí odkaz:
https://doaj.org/article/146a81abe8614f6fa11465cbd75ea3a6
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract In triple-negative breast cancer (TNBC), the tumor microenvironment is associated with increased proliferation, suppressing apoptotic mechanisms, an altered immune response, and drug resistance. The current investigation was designed to exam
Externí odkaz:
https://doaj.org/article/90de7676659e41719b560b06c9e9ad53
Publikováno v:
Brain Sciences, Vol 13, Iss 1, p 145 (2023)
Neurodegenerative diseases (ND) include a wide range of conditions that result from progressive damage to the neurons. Alzheimer’s disease (AD) is one of the most common NDs, and neuroinflammation and oxidative stress (OS) are the major factors in
Externí odkaz:
https://doaj.org/article/ae1e73725c55463ab0303a8a69b8da6b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16091 (2022)
Cancer accounts for one in seven deaths worldwide and is the second leading cause of death in the United States, after heart disease. One of the standard cancer treatments is chemotherapy which sometimes can lead to chemoresistance and treatment fail
Externí odkaz:
https://doaj.org/article/4b19b68ad5c642e8a9f0bfd7339b190a
Publikováno v:
Nutrients, Vol 14, Iss 11, p 2228 (2022)
Neurodegenerative disorders affect more than fifty million Americans each year and represent serious health threats as the population ages. Neuroinflammation and oxidative stress are critical in the onset, progression, and pathogenesis of neurodegene
Externí odkaz:
https://doaj.org/article/2eb9a2bdf2034c0398c685f662afdca9
Autor:
Selina F. Darling-Reed, Yasmeen Nkrumah-Elie, Dominique T. Ferguson, Hernan Flores-Rozas, Patricia Mendonca, Samia Messeha, Alicia Hudson, Ramesh B. Badisa, Syreeta L. Tilghman, Tracy Womble, Agnes Day, Marti Jett, Rasha Hammamieh, Karam F. A. Soliman
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1313 (2021)
Garlic has long been used medicinally for many diseases, including cancer. One of the active garlic components is diallyl sulfide (DAS), which prevents carcinogenesis and reduces the incidence rate of several cancers. In this study, non-cancerous MCF
Externí odkaz:
https://doaj.org/article/5e088a7625db4061884aa98de67868b5