Zobrazeno 1 - 8
of 8
pro vyhledávání: '"PARK7 protein, human"'
Autor:
Ebba Lohmann, Peter Heutink, Murat Emre, Thomas Gasser, Hasmet Hanagasi, Başar Bilgiç, Ece Kartal, Javier Simón-Sánchez, Nazli Basak, Gamze Guven, Anamika Giri, Ann-Kathrin Hauser
Publikováno v:
Parkinsonism & related disorders 29, 117-120 (2016). doi:10.1016/j.parkreldis.2016.03.001
Objective DJ1 mutations (PARK7) are among the monogenic causes of early-onset autosomal recessive parkinsonism. Here, we report clinical and genetic findings in a family with Turkish origin carrying a new DJ1 mutation and presenting with early-onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5896d583c49c3c3341606b3cc03e31
https://doi.org/10.1016/j.parkreldis.2016.03.001
https://doi.org/10.1016/j.parkreldis.2016.03.001
Autor:
Franc Llorens, Inga Zerr, Olivier Andreoletti, Niels Kruse, Waqas Tahir, Saima Zafar, Katrin Thüne, Matthias Schmitz, Nadine Gotzmann, Isidre Ferrer, Juan María Torres, Brit Mollenhauer, Amandeep Singh Arora
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
Recercat. Dipósit de la Recerca de Catalunya
instname
INIA: Repositorio de Resultados de Investigación del INIA
Molecular neurobiology 55(1), 517-537 (2016). doi:10.1007/s12035-016-0294-4
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2018, 55 (1), pp.517-537. ⟨10.1007/s12035-016-0294-4⟩
Universidad de Barcelona
Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
Recercat. Dipósit de la Recerca de Catalunya
instname
INIA: Repositorio de Resultados de Investigación del INIA
Molecular neurobiology 55(1), 517-537 (2016). doi:10.1007/s12035-016-0294-4
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2018, 55 (1), pp.517-537. ⟨10.1007/s12035-016-0294-4⟩
International audience; Cerebellar damage and granular and Purkinje cell loss in sporadic Creutzfeldt-Jakob disease (sCJD) highlight a critical involvement of the cerebellum during symptomatic progression of the disease. In this project, global prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e70d20e34e430227363477c22cb52c
http://hdl.handle.net/2445/141809
http://hdl.handle.net/2445/141809
Autor:
Gereon Poschmann, Jens Wiltfang, Wolfgang Wurst, Katrin Seyfarth, Helmut E. Meyer, D. Besong Agbo, Martin Klingenspor, Just Genius, Hans-Wolfgang Klafki, C. Janßen, Kai Stühler
Publikováno v:
Analytical biochemistry 443(2), 197-204 (2013). doi:10.1016/j.ab.2013.09.013
We report on the development of a novel assay protocol for the separation and detection of charge isoforms of DJ-1 in biological samples by automated capillary isoelectric focusing followed by immunological detection. DJ-1 (PARK7) is considered as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7385d47aa3b3a7dc1bd80bf66560df82
https://doi.org/10.1016/j.ab.2013.09.013
https://doi.org/10.1016/j.ab.2013.09.013
Autor:
Dominik Piston, Lydia Alvarez-Erviti, Vikas Bansal, Daniela Gargano, Zhi Yao, Gyorgy Szabadkai, Mark Odell, M Rhyan Puno, Benny Björkblom, Jodi Maple-Grødem, Peter Breuer, Oliver Kaut, Jan Petter Larsen, Stefan Bonn, Simon Geir Møller, Ullrich Wüllner, Anthony H V Schapira, Matthew E Gegg
Publikováno v:
Human molecular genetics 26(20), 4028-4041 (2017). doi:10.1093/hmg/ddx294
Human Molecular Genetics
Human Molecular Genetics
DJ-1 is an oxidation sensitive protein encoded by the PARK7 gene. Mutations in PARK7 are a rare cause of familial recessive Parkinson's disease (PD), but growing evidence suggests involvement of DJ-1 in idiopathic PD. The key clinical features of PD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589ee14d3b19c486a0ae29a58189184b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-140877
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-140877
Autor:
Nora Wender, Tim Bartels, Jan Hegermann, Konstanze F. Winklhofer, Christian Haass, Bettina Brunner, Frits Kamp, Anne Kathrin Lutz, Nicole Exner, Brigitte Nuscher, Armin Giese, Stefan Eimer, Klaus Beyer
Publikováno v:
The EMBO journal 29(20), 3571-3589 (2010). doi:10.1038/emboj.2010.223
Aggregation of α-synuclein (αS) is involved in the pathogenesis of Parkinson's disease (PD) and a variety of related neurodegenerative disorders. The physiological function of αS is largely unknown. We demonstrate with in vitro vesicle fusion expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671a792c16e87456464177b9e6869f43
https://doi.org/10.1038/emboj.2010.223
https://doi.org/10.1038/emboj.2010.223
Autor:
Elif Demirdogen, Mehmet Zarifoglu, Unal Egeli, Gulsah Cecener, Sevda Erer, Berrin Tunca, Okan Dogu, Gulcin Tezcan, Secil Ak, Esen Saka, Hakan Kaleagasi, Bulent Elibol, Gülay Kenangil
Publikováno v:
Clinical neurology and neurosurgery. 148
Objective Variations in PARK genes ( PRKN , PINK1 , DJ-1, and SNCA ) cause early-onset Parkinson's disease (EOPD) in different populations. In the current study, we aimed to evaluate the frequencies of variations in PARK genes and the effects of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9af2eaed1ea4e510ca0ccd7bd32fc4
https://pubmed.ncbi.nlm.nih.gov/27455133
https://pubmed.ncbi.nlm.nih.gov/27455133
Autor:
Karina Fog, Emmy Helena Rannikko, Philipp J. Kahle, Stephanie Weber, Louise Buur Vesterager, Poul Henning Jensen, Jafar H. A. Shaik, Elena M. Cornejo Castro
Publikováno v:
Journal of neurochemistry 125(2), 314-327 (2013). doi:10.1111/jnc.12126
Journal of Neurochemistry; Vol 125
Rainnikko, E H, Vesterager, L B, Shaik, J H A, Stephanie S., W, Cornejo Castro, E M, Fog, K, Jensen, P H & Kahle, P J 2013, ' Loss of DJ-1 protein stability and cytoprotective function by Parkinson’s disease-associated proline-158 deletion ', Journal of Neurochemistry, vol. 10.1111 . https://doi.org/10.1111/jnc.12126
Journal of Neurochemistry
Journal of Neurochemistry; Vol 125
Rainnikko, E H, Vesterager, L B, Shaik, J H A, Stephanie S., W, Cornejo Castro, E M, Fog, K, Jensen, P H & Kahle, P J 2013, ' Loss of DJ-1 protein stability and cytoprotective function by Parkinson’s disease-associated proline-158 deletion ', Journal of Neurochemistry, vol. 10.1111 . https://doi.org/10.1111/jnc.12126
Journal of Neurochemistry
DJ-1 is a ubiquitous protein regulating cellular viability. Recessive mutations in the PARK7/DJ-1 gene are linked to Parkinson's disease (PD). Although the most dramatic L166P point mutation practically eliminates DJ-1 protein and function, the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede435f9de8a938836f281867c9ddd22
https://pub.dzne.de/record/136869
https://pub.dzne.de/record/136869
Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury
Autor:
Su Jung Woo, Hoon Jae Jeong, So Mi Kim, Sung-Woo Cho, Moo-Ho Won, Won Sik Eum, Soo Young Choi, Hyo Sang Jo, Kyu Hyung Han, Dae Won Kim, Mi Jin Kim, Jin Seu Park, Duk Soo Kim, Hyun Sook Hwang, Hye Ri Kim
Publikováno v:
Experimental & Molecular Medicine
Reactive oxygen species (ROS) contribute to the development of a number of neuronal diseases including ischemia. DJ-1, also known to PARK7, plays an important role in transcriptional regulation, acting as molecular chaperone and antioxidant. In the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e9769407214c0c39c7298f66913547
https://doi.org/10.3858/emm.2012.44.10.067
https://doi.org/10.3858/emm.2012.44.10.067