Zobrazeno 1 - 10
of 1 009
pro vyhledávání: '"PARG"'
Publikováno v:
OncoTargets and Therapy, Vol Volume 17, Pp 741-753 (2024)
Pisong Li, Xiaoyu Zhu, Hui Qu, Zhongbin Han, Xingyu Yao, Yuan Wei, Baijun Li, Hongshen Chen Department of Breast and Thyroid Surgery, Affiliated Zhongshan Hospital of Dalian University, Dalian, 116001, People’s Republic of ChinaCorrespondence: Hong
Externí odkaz:
https://doaj.org/article/c2f9461f2bbe48a88a505b984a975d2c
Autor:
Rafael Dias de Moura, Priscilla Doria de Mattos, Penélope Ferreira Valente, Nícolas Carlos Hoch
Publikováno v:
Genetics and Molecular Biology, Vol 47, Iss suppl 1 (2024)
Abstract Regulated cell death by a non-apoptotic pathway known as parthanatos is increasingly recognised as a central player in pathological processes, including ischaemic tissue damage and neurodegenerative diseases. Parthanatos is activated under c
Externí odkaz:
https://doaj.org/article/6c4c728e07944110a9d6c7e63c1c057c
Autor:
Litong Nie, Chao Wang, Min Huang, Xiaoguang Liu, Xu Feng, Mengfan Tang, Siting Li, Qinglei Hang, Hongqi Teng, Xi Shen, Li Ma, Boyi Gan, Junjie Chen
Publikováno v:
eLife, Vol 12 (2024)
Poly(ADP-ribose)ylation or PARylation by PAR polymerase 1 (PARP1) and dePARylation by poly(ADP-ribose) glycohydrolase (PARG) are equally important for the dynamic regulation of DNA damage response. PARG, the most active dePARylation enzyme, is recrui
Externí odkaz:
https://doaj.org/article/92e85ce7326f405eb84500e2b50e7d5b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Guillaume Bordet, Alexei V. Tulin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6189 (2024)
Aging, marked by a gradual decline in physiological function and heightened vulnerability to age-related diseases, remains a complex biological process with multifaceted regulatory mechanisms. Our study elucidates the critical role of poly(ADP–ribo
Externí odkaz:
https://doaj.org/article/9a6640e71e4a4f9d909663b036402ffe
Autor:
Parisi A, Rossi F, De Filippis C, Paoloni F, Felicetti C, Mammarella A, Pecci F, Lupi A, Berardi R
Publikováno v:
OncoTargets and Therapy, Vol Volume 16, Pp 585-613 (2023)
Alessandro Parisi, Francesca Rossi, Chiara De Filippis, Francesco Paoloni, Cristiano Felicetti, Alex Mammarella, Federica Pecci, Alessio Lupi, Rossana Berardi Department of Clinical Oncology, Università Politecnica delle Marche, Azienda Ospedaliero
Externí odkaz:
https://doaj.org/article/da93fecb60bc4753b4dcc79c0e103371
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17205 (2023)
Hepatocellular carcinoma (HCC) is a major global health concern, representing one of the leading causes of cancer-related deaths. Despite various treatment options, the prognosis for HCC patients remains poor, emphasizing the need for a deeper unders
Externí odkaz:
https://doaj.org/article/c0cf1cc541cc4787bd1b3886b82905fd
Autor:
Sarah Johnson, Yaroslava Karpova, Danping Guo, Atreyi Ghatak, Dmitriy A. Markov, Alexei V. Tulin
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metasta
Externí odkaz:
https://doaj.org/article/556c762c69cf449d9c1284bce015a7fb
Publikováno v:
Cancer Reports, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background Poly(ADP‐ribose) glycohydrolase (PARG) is a key enzyme in poly(ADP‐ribose) (PAR) metabolism and a potential anticancer target. Many drug candidates have been developed to inhibit its enzymatic activity. Additionally, PDD000172
Externí odkaz:
https://doaj.org/article/e84445096a35457abc37c84e8e9eeab3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.