Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1

Autor: Ilaria De Simone, Constance C. F. M. J. Baaten, Martine Jandrot-Perrus, Jonathan M. Gibbins, Hugo ten Cate, Johan W. M. Heemskerk, Chris I. Jones, Paola E. J. van der Meijden

Publikováno v: International journal of molecular sciences 23(18), 10203 (2022). doi:10.3390/ijms231810203 special issue: "Special Issue "Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation 2.0" / Special Issue Editors: Dr. Kerstin Jurk, Guest Editor; Dr. Marijke J.E. Kuijpers, Guest Editor; Prof. Dr. Johan W. M. Heemskerk, Guest Editor"
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10203
International journal of molecular sciences, 23(18):10203. Multidisciplinary Digital Publishing Institute (MDPI)

International journal of molecular sciences 23(18), 10203 (2022). doi:10.3390/ijms231810203 special issue: "Special Issue "Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation 2.0" / Special Issue Editors: Dr. Kerstin Jurk, Guest E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6f435355a06d55d0ea586c2d31dad1

Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development

Autor: Tomas L. Lindahl, Sofia Ramström, Maria Bjerke, Karin Vretenbrant

SummaryThrombin is a pivotal enzyme formed in the coagulation cascade and an important and potent platelet activator. The two pro-tease-activated thrombin receptors on human platelets are denoted PARI and PAR4. The physiological relevance of PAR4 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0a5fdcec10d8e96e9ac7a5dd52255c
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-39478