Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset

Autor: Paola Forabosco, Mauro Pala, Francesca Crobu, Maria Antonietta Diana, Mara Marongiu, Roberto Cusano, Andrea Angius, Maristella Steri, Valeria Orrù, David Schlessinger, Edoardo Fiorillo, Marcella Devoto, Francesco Cucca

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Gene co-expression network analysis enables identification of biologically meaningful clusters of co-regulated genes (modules) in an unsupervised manner. We present here the largest study conducted thus far of co-expression networks in white blood ce

Externí odkaz: https://doaj.org/article/3199be89b03f4f1bac21ab97e924be4c

Correction: Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking.

Autor: Ian C. Scott, Seth D. Seegobin, Sophia Steer, Rachael Tan, Paola Forabosco, Anne Hinks, Stephen Eyre, Ann W. Morgan, Anthony G. Wilson, Lynne J. Hocking, Paul Wordsworth, Anne Barton, Jane Worthington, Andrew P. Cope, Cathryn M. Lewis

Publikováno v: PLoS Genetics, Vol 9, Iss 10 (2013)

Externí odkaz: https://doaj.org/article/dea36ebbb53f4fdab84e7fb35c8ce65a

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA).

Autor: Ebun Omoyinmi, Paola Forabosco, Raja Hamaoui, Annette Bryant, Anne Hinks, Simona Ursu, Childhood Arthritis Prospective Study (CAPS), BSPAR study group, Childhood Arthritis Response to Medication Study (CHARMS), Lucy R Wedderburn, Wendy Thomson, Cathryn M Lewis, Patricia Woo

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e47673 (2012)

BackgroundThe cytokine IL-10 and its family members have been implicated in autoimmune diseases and we have previously reported that genetic variants in IL-10 were associated with a rare group of diseases called juvenile idiopathic arthritis (JIA). T

Externí odkaz: https://doaj.org/article/68848ac2dda2488597842d2648905178

A Sardinian founder mutation in glycoprotein Ib platelet subunit beta(GP1BB) that impacts thrombocytopenia

Autor: Fabio Busonero, Marco Masala, Gabriella Sole, Serena Sanna, Valeria Orrù, Cristian Antonio Caria, Michele Marongiu, Magdalena Zoledziewska, Isadora Asunis, Carlo Sidore, Paola Forabosco, Mauro Pala, Gonçalo R. Abecasis, Edoardo Fiorillo, Maristella Pitzalis, Sandra Lai, Francesca Deidda, Antonella Mulas, Matteo Floris, Maristella Steri, Andrea Maschio, Susanna Barella, David Schlessinger, Stefania Olla, Francesco Cucca

Publikováno v: British Journal of Haematology, e124-e128. Wiley
ISSUE=5;STARTPAGE=e124;ENDPAGE=e128;ISSN=0007-1048;TITLE=British Journal of Haematology
Br J Haematol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0dd166dd9b501b6edd7d1dcbb8eb18
https://doi.org/10.1111/bjh.17090

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

Autor: Leonardo Collado-Torres, Oluwadamilola Ojo, Huw Morris, Andy Thomason, Isabel Gonzalez-Aramburu, Mie Rizig, Sara Bandrés Ciga, Patrick Lewis, María Teresa Periñán, Pau Pastor, Nicholas Wood, Kerrin Small, John Quinn, PAOLA FORABOSCO, Rubén Fernández-Santiago, Astrid Daniela Adarmes Gómez, Juan Carlos Martinez Castrillo, Sonja Scholz, Victoria Alvarez, Niccolò Emanuele Mencacci, Michael Weale, Thomas Gasser, Kari Majamaa, Adolfo Mínguez-Castellanos, Jose Bras, J. Raphael Gibbs, Monica Diez-Fairen, Ruth Lovering, Jon Infante, Juan A. Botía, Rita Guerreiro, John Hardy, Mario Ezquerra, Valentina Escott-Price, Arianna Tucci, Kin Ying Mok, Kerri J Kinghorn, Manuel Menéndez González, Janet Hoenicka, Njideka Okubadejo, Regina Reynolds, Alexis Brice, Ignacio Alvarez, Adaikalavan Ramasamy, Pille Taba, David Zhang, Lydia Vela-Desojo

Publikováno v: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Guelfi, S, D’sa, K, Botía, J A, Vandrovcova, J, Reynolds, R H, Zhang, D, Trabzuni, D, Collado-torres, L, Thomason, A, Quijada Leyton, P, Gagliano Taliun, S A, Nalls, M A, Small, K S, Smith, C, Ramasamy, A, Hardy, J, Weale, M E & Ryten, M 2020, ' Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-14483-x
Nature communications, vol 11, iss 1
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications 11, 1041 (2020).
UCrea Repositorio Abierto de la Universidad de Cantabria
Nature communications

International Parkinson’s Disease Genomics Consortium (IPDGC), UK Brain Expression Consortium (UKBEC).
Genome-wide association studies have generated an increasing number of common genetic variants associated with neurological and psychiatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983ce5373a8661d389b6fcfe05e9de4f
https://doi.org/10.1038/s41467-020-14483-x