Targeting organ-specific mitochondrial dysfunction to improve biological aging.

Autor: Madreiter-Sokolowski CT; Division of Molecular Biology and Biochemistry, Medical University of Graz, BioTechMed-Graz, Austria. Electronic address: corina.madreiter@medunigraz.at., Hiden U; Department of Obstetrics and Gynecology, Research Unit of Early Life Determinants, Medical University of Graz, Austria., Krstic J; Division of Cell Biology, Histology and Embryology, Medical University of Graz, BioTechMed-Graz, Austria., Panzitt K; Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria., Wagner M; Division of Gastroenterology and Hepatology, Medical University of Graz, Austria., Enzinger C; Department of Neurology, Medical University of Graz, Austria., Khalil M; Department of Neurology, Medical University of Graz, Austria., Abdellatif M; Division of Cardiology, Medical University of Graz, BioTechMed-Graz, Austria., Malle E; Division of Molecular Biology and Biochemistry, Medical University of Graz, BioTechMed-Graz, Austria., Madl T; Division of Medicinal Chemistry, Medical University of Graz, BioTechMed-Graz, Austria., Osto E; Division of Physiology and Pathophysiology, Medical University of Graz., Schosserer M; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Austria; Christian Doppler Laboratory for Skin Multimodal Imaging of Aging and Senescence, Austria., Binder CJ; Department of Laboratory Medicine, Medical University of Vienna, Austria., Olschewski A; Department of Anesthesiology and Intensive Care Medicine, LBI for Lung Vascular Research, Medical University of Graz, Austria. Electronic address: andrea.olschewski@medunigraz.at.

Publikováno v: Pharmacology & therapeutics [Pharmacol Ther] 2024 Oct; Vol. 262, pp. 108710. Date of Electronic Publication: 2024 Aug 22.

Recent advances on FXR-targeting therapeutics.

Autor: Panzitt K; Research Unit for Translational Nuclear Receptor Research, Medical University Graz, Graz, Austria; Division of Gastroenterology and Hepatology, Medical University Graz, Graz, Austria., Zollner G; Division of Gastroenterology and Hepatology, Medical University Graz, Graz, Austria., Marschall HU; Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Wagner M; Research Unit for Translational Nuclear Receptor Research, Medical University Graz, Graz, Austria; Division of Gastroenterology and Hepatology, Medical University Graz, Graz, Austria. Electronic address: martin.wagner@medunigraz.at.

Publikováno v: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2022 Jul 15; Vol. 552, pp. 111678. Date of Electronic Publication: 2022 May 20.

Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor.

Autor: Greimel T; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Jahnel J; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Pohl S; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Strini T; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Tischitz M; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Meier-Allard N; Division of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University Graz, Graz, Austria., Holasek S; Division of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University Graz, Graz, Austria., Meinel K; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Aguiriano-Moser V; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Zobel J; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Haidl H; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Gallistl S; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria., Panzitt K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University Graz, Graz, Austria., Wagner M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University Graz, Graz, Austria., Schlagenhauf A; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria. axel.schlagenhauf@medunigraz.at.

Publikováno v: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2021 Oct; Vol. 101 (10), pp. 1394-1402. Date of Electronic Publication: 2021 Jun 18.

Pharmacological Mechanisms of Bile Acids Targeting the Farnesoid X Receptor.

Autor: Qi, Youchao^1,2,3,4,5 (AUTHOR) 2020990013@qhu.edu.cn, Ma, Yonggui^4,5 (AUTHOR), Duan, Guozhen^2,3 (AUTHOR) 2019990045@qhu.edu.cn

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13656. 18p.

Endothelial Dysfunction and Liver Cirrhosis: Unraveling of a Complex Relationship.

Autor: Nesci, Antonio¹ (AUTHOR), Ruggieri, Vittorio¹ (AUTHOR), Manilla, Vittoria² (AUTHOR), Spinelli, Irene² (AUTHOR), Santoro, Luca¹ (AUTHOR), Di Giorgio, Angela¹ (AUTHOR), Santoliquido, Angelo^1,3 (AUTHOR), Ponziani, Francesca Romana^2,3 (AUTHOR) francesca.ponziani@gmail.com

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12859. 21p.