Zobrazeno 1 - 10
of 332
pro vyhledávání: '"PANX1"'
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Pannexin1 (PANX1) is a highly glycosylated membrane channel-forming protein, which has been found to implicate in multiple physiological and pathophysiological functions. Variants in the PANX1 gene have been reported to be associated with oo
Externí odkaz:
https://doaj.org/article/15862c34e3b44209aa0d2f01f3734e20
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/84d26d45012e42eca3a47e01208a5660
Autor:
Cheng-Qing Hu, Tao Hou, Rui Xiang, Xin Li, Jing Li, Tian-Tian Wang, Wen-Jun Liu, Song Hou, Di Wang, Qing-He Zhao, Xiao-Xing Yu, Ming Xu, Xing-Kai Liu, Yu-Jing Chi, Ji-Chun Yang
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-26 (2024)
Abstract Background Extracellular adenosine triphosphate (ATP) is an important signal molecule. In previous studies, intensive research had revealed the crucial roles of family with sequence similarity 3 member A (FAM3A) in controlling hepatic glucol
Externí odkaz:
https://doaj.org/article/f122ea0858ba4deab168681c1c964751
Autor:
Qu Xing, Antonio Cibelli, Greta Luyuan Yang, Preeti Dohare, Qing-Hua Li, Eliana Scemes, Fang-Xia Guan, David C. Spray
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-16 (2024)
Abstract Background The channel-forming protein Pannexin1 (Panx1) has been implicated in both human studies and animal models of chronic pain, but the underlying mechanisms remain incompletely understood. Methods Wild-type (WT, n = 24), global Panx1
Externí odkaz:
https://doaj.org/article/d51e0c3456d9496184d8ab31b7ea130d
Autor:
Claudia M. Lucero, Laura Navarro, Cristián Barros-Osorio, Patricio Cáceres-Conejeros, Juan A. Orellana, Gonzalo I. Gómez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Chronic kidney disease (CKD) is a prevalent health concern associated with various pathological conditions, including hypertensive nephropathy. Mesangial cells are crucial in maintaining glomerular function, yet their involvement in CKD pathogenesis
Externí odkaz:
https://doaj.org/article/e4c68d29d50c4fca9a92c2095aea4f94
Akademický článek
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Publikováno v:
Channels, Vol 17, Iss 1 (2023)
ABSTRACTMany neurological conditions exhibit synaptic impairments, suggesting mechanistic convergence. Additionally, the pannexin 1 (PANX1) channel and signaling scaffold is linked to several of these neurological conditions and is an emerging regula
Externí odkaz:
https://doaj.org/article/dd54ed127c554e1f90dbb9206c3133fb
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Sepsis represents a global health concern, and patients with severe sepsis are at risk of experiencing MODS (multiple organ dysfunction syndrome), which is associated with elevated mortality rates and a poorer prognosis. The development of sepsis inv
Externí odkaz:
https://doaj.org/article/02e221a978aa46bd874ae89680817dde
Autor:
Julia Borges Paes Lemes, Kaue Franco Malange, Nathalia Santos Carvalho, Amanda Ferreira Neves, Marcia Urban-Maldonado, Paula Regina Gelinski Kempe, Catarine Massucato Nishijima, Cecilia Costa Fagundes, Celina Monteiro da Cruz Lotufo, Sylvia Ottile Suadicani, Carlos Amilcar Parada
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 3, p 64 (2024)
Background: Pannexin1 (Panx1) is a membrane channel expressed in different cells of the nervous system and is involved in several pathological conditions, including pain and inflammation. At the central nervous system, the role of Panx1 is already we
Externí odkaz:
https://doaj.org/article/4254c33da3564e0bb80a3e371ce9ed2d
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 108 (2024)
Immunogenic death (ICD) stimulates adaptive immunity and affects immunotherapeutic efficacy, an important part of which is damage-associated molecular patterns (DAMPs). However, the function of these DAMPs for lung adenocarcinoma (LUAD) remains obscu
Externí odkaz:
https://doaj.org/article/ffcfedab37984c4c92ba7c3423f190e6