Zobrazeno 1 - 10
of 177
pro vyhledávání: '"PANDHA, H.S."'
Yes
The HOX genes are a group of homeodomain-containing transcription factors that play important regulatory roles in early development, including the establishment of cell and tissue identity. HOX expression is generally reduced in adult cells
The HOX genes are a group of homeodomain-containing transcription factors that play important regulatory roles in early development, including the establishment of cell and tissue identity. HOX expression is generally reduced in adult cells
Externí odkaz:
http://hdl.handle.net/10454/17038
Yes
Engrailed-2 (EN2) is a homeodomain-containing transcription factor that has roles in boundary formation and neural guidance in early development, but which is also expressed in a range of cancers. In addition to transcriptional regulation, i
Engrailed-2 (EN2) is a homeodomain-containing transcription factor that has roles in boundary formation and neural guidance in early development, but which is also expressed in a range of cancers. In addition to transcriptional regulation, i
Externí odkaz:
http://hdl.handle.net/10454/16958
Autor:
Kelly, Z., Moller-Levet, C., McGrath, S., Butler-Manuel, S., Madhuri, T.K., Kierzek, A.M., Pandha, H.S., Morgan, Richard, Michael, A.
Yes
HOX genes are vital for all aspects of mammalian growth and differentiation, and their dysregulated expression is related to ovarian carcinogenesis. The aim of the current study was to establish the prognostic value of HOX dysregulation as w
HOX genes are vital for all aspects of mammalian growth and differentiation, and their dysregulated expression is related to ovarian carcinogenesis. The aim of the current study was to establish the prognostic value of HOX dysregulation as w
Externí odkaz:
http://hdl.handle.net/10454/9921
Autor:
Morgan, Richard, Simpson, G.R., Gray, S., Gillett, C., Tabi, Z., Spicer, J., Harrington, K.J., Pandha, H.S.
Yes
Background The HOX genes are a family of homeodomain-containing transcription factors that determine cellular identity during development and which are dys-regulated in some cancers. In this study we examined the expression and oncogenic fun
Background The HOX genes are a family of homeodomain-containing transcription factors that determine cellular identity during development and which are dys-regulated in some cancers. In this study we examined the expression and oncogenic fun
Externí odkaz:
http://hdl.handle.net/10454/8603
Autor:
Morgan, Richard, Pandha, H.S.
Yes
It is now well established that the tumor microenvironment plays an essential role in the survival, growth, invasion, and spread of cancer through the regulation of angiogenesis and localized immune responses. This review examines the role o
It is now well established that the tumor microenvironment plays an essential role in the survival, growth, invasion, and spread of cancer through the regulation of angiogenesis and localized immune responses. This review examines the role o
Externí odkaz:
http://hdl.handle.net/10454/14281
Autor:
Alharbi, R.A., Pandha, H.S., Simpson, G.R., Pettengell, R., Poterlowicz, Krzysztof, Thompson, A., Harrington, K.J., El-Tanani, Mohamed, Morgan, Richard
Yes
The HOX genes encode a family of transcription factors that have key roles in both development and malignancy. Disrupting the interaction between HOX proteins and their binding partner, PBX, has been shown to cause apoptotic cell death in a
The HOX genes encode a family of transcription factors that have key roles in both development and malignancy. Disrupting the interaction between HOX proteins and their binding partner, PBX, has been shown to cause apoptotic cell death in a
Externí odkaz:
http://hdl.handle.net/10454/13040
Yes
The HOX and PBX gene families encode transcription factors that have key roles in establishing the identity of cells and tissues in early development. Over the last 20 years it has become apparent that they are also dysregulated in a wide ra
The HOX and PBX gene families encode transcription factors that have key roles in establishing the identity of cells and tissues in early development. Over the last 20 years it has become apparent that they are also dysregulated in a wide ra
Externí odkaz:
http://hdl.handle.net/10454/11620
Autor:
De Paoli, M., Perco, P., Mühlberger, I., Lukas, A., Pandha, H.S., Morgan, Richard, Feng, G.J., Marquette, C.
Yes
Context: Urinary biomarkers are promising as simple alternatives to cystoscopy for the diagnosis of de novo and recurrent bladder cancer. Objective: To identify a highly sensitive and specific biomarker candidate set with potential clinical
Context: Urinary biomarkers are promising as simple alternatives to cystoscopy for the diagnosis of de novo and recurrent bladder cancer. Objective: To identify a highly sensitive and specific biomarker candidate set with potential clinical
Externí odkaz:
http://hdl.handle.net/10454/9897
Yes
Background: The HOX genes are a family of transcription factors that help to determine cell and tissue identity during early development, and which are also over-expressed in a number of malignancies where they have been shown to promote cel
Background: The HOX genes are a family of transcription factors that help to determine cell and tissue identity during early development, and which are also over-expressed in a number of malignancies where they have been shown to promote cel
Externí odkaz:
http://hdl.handle.net/10454/9886
Autor:
Pandha, H.S., Javed, S., Sooriakumaran, P., Bott, S., Montgomery, B., Hutton, A., Eden, C., Langley, S.E., Morgan, Richard
Yes
The aim of this study was to assess the relationship between pre-prostatectomy urinary Engrailed-2 (EN2), a transcription factor secreted by prostate cancer cells, with tumour volume and pathological characteristics in resected prostate spec
The aim of this study was to assess the relationship between pre-prostatectomy urinary Engrailed-2 (EN2), a transcription factor secreted by prostate cancer cells, with tumour volume and pathological characteristics in resected prostate spec
Externí odkaz:
http://hdl.handle.net/10454/10105