Výsledky vyhledávání - "PANCREATIC-ISLETS"

Akademický článek

Human pancreatic islet-derived stromal cells reveal combined features of mesenchymal stromal cells and pancreatic stellate cells

Autor: Nour Ebrahim, Nikolay Kondratyev, Alexander Artyuhov, Alexei Timofeev, Nadya Gurskaya, Alexey Andrianov, Roman Izrailov, Egor Volchkov, Tatyana Dyuzheva, Elena Kopantseva, Ekaterina Kiseleva, Vera Golimbet, Erdem Dashinimaev

Publikováno v: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Background Mesenchymal stromal cells (MSCs) are recognized for their potential in regenerative medicine, attributed to their multipotent differentiation capabilities and immunomodulatory properties. Despite this potential, the classification

Externí odkaz: https://doaj.org/article/8599933f3e78417799be8b84324609da

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Akademický článek

Immunodetection of selected pancreatic hormones under intragastric administration of apelin-13, a novel endogenous ligand for an angiotensin-like orphan G-protein coupled receptor, in unweaned rats

Autor: Szymańczyk Sylwia, Kras Katarzyna, Osiak-Wicha Cezary, Kapica Małgorzata, Puzio Iwona, Antushevich Hanna, Kuwahara Atsukazu, Kato Ikuo, Arciszewski Marcin B.

Publikováno v: Journal of Veterinary Research, Vol 68, Iss 3, Pp 461-468 (2024)

This study investigated the effects of intragastric administration of apelin-13 on the secretion of critical pancreatic hormones in a cohort of three-week-old Wistar rats. The research aimed to uncover apelin’s modulatory roles in endocrine interac

Externí odkaz: https://doaj.org/article/2a0371943eec4932ac9e3effe545e993

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Akademický článek

Pancreatic β-cells package double C2-like domain beta protein into extracellular vesicles via tandem C2 domains

Autor: Diana Esparza, Carinna Lima, Sarah Abuelreich, Ima Ghaeli, Jinhee Hwang, Eunjin Oh, Ayelet Lenz, Angel Gu, Nan Jiang, Fouad Kandeel, Debbie C. Thurmond, Tijana Jovanovic-Talisman

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

IntroductionDouble C2-like domain beta (DOC2B) is a vesicle priming protein critical for glucose-stimulated insulin secretion in β-cells. Individuals with type 1 diabetes (T1D) have lower levels of DOC2B in their residual functional β-cell mass and

Externí odkaz: https://doaj.org/article/49be9d7536124d169961b687cb510217

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Akademický článek

Effect of Ajwa Date (Phoenix dactylifera) Extract on the Histopathology of Pancreatic Islets in Mice with Diabetes Mellitus

Autor: Nadhifa Arna, Ira Humairah, Joni Susanto, Tri Hartini Yuliawati

Publikováno v: Current Internal Medicine Research and Practice Surabaya Journal, Vol 5, Iss 2 (2024)

Introduction: It is necessary to develop alternative antidiabetic therapies that are safer and more affordable to overcome the high prevalence of diabetes mellitus in Indonesia. Ajwa dates (Phoenix dactylifera) have a high flavonoid content; hence, t

Externí odkaz: https://doaj.org/article/2bdd738bbe1d4cb5a8816571a40d125e

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Akademický článek

Immunoprotection Strategies in β‐Cell Replacement Therapy: A Closer Look at Porcine Islet Xenotransplantation

Autor: Sarah Grimus, Victoria Sarangova, Petra B. Welzel, Barbara Ludwig, Jochen Seissler, Elisabeth Kemter, Eckhard Wolf, Asghar Ali

Publikováno v: Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)

Abstract Type 1 diabetes mellitus (T1DM) is characterized by absolute insulin deficiency primarily due to autoimmune destruction of pancreatic β‐cells. The prevailing treatment for T1DM involves daily subcutaneous insulin injections, but a substan

Externí odkaz: https://doaj.org/article/81d8d2b5304a4da893a6f63d70c7a318

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