Zobrazeno 1 - 4
of 4
pro vyhledávání: '"PALB2, partner and localizer of BRCA2"'
Autor:
Hao Wang, Lei Wang, Keyi Jia, Yu Liu, Sha Zhao, Wei Li, Caicun Zhou, Minlin Jiang, Bin Chen, Yayi He
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Genomic instability remains an enabling feature of cancer and promotes malignant transformation. Alterations of DNA damage response (DDR) pathways allow genomic instability, generate neoantigens, upregulate the expression of programmed death ligand 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe73202674a833d134ec811bcbf7332
https://doi.org/10.1016/j.apsb.2021.01.003
https://doi.org/10.1016/j.apsb.2021.01.003
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76811ce2af0ea0f7b3342230007c3c01
https://doi.org/10.1016/j.addr.2021.03.018
https://doi.org/10.1016/j.addr.2021.03.018
Autor:
Weixing Zhao, Platon Selemenakis, Bo Wu, Yuxin Huang, Dauren S. Alimbetov, Claudia Wiese, Elena Pires, Neelam Sharma
Publikováno v:
The Journal of Biological Chemistry
RAD51-associated protein 1 (RAD51AP1) is a key protein in the homologous recombination (HR) DNA repair pathway. Loss of RAD51AP1 leads to defective HR, genome instability, and telomere erosion. RAD51AP1 physically interacts with the RAD51 recombinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb0e26ebb5ecc8d72fa33747d201bf9
http://europepmc.org/articles/PMC8233230
http://europepmc.org/articles/PMC8233230
Autor:
Jiang M; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.; Medical School, Tongji University, Shanghai 200433, China., Jia K; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.; Medical School, Tongji University, Shanghai 200433, China., Wang L; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China., Li W; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China., Chen B; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China., Liu Y; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.; Medical School, Tongji University, Shanghai 200433, China., Wang H; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.; Medical School, Tongji University, Shanghai 200433, China., Zhao S; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China., He Y; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China., Zhou C; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Oct; Vol. 11 (10), pp. 2983-2994. Date of Electronic Publication: 2021 Jan 06.