Zobrazeno 1 - 10
of 33
pro vyhledávání: '"PAH, polycyclic aromatic hydrocarbon"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 19-32 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Microbes inhabiting the intestinal tract of humans represent a site for xenobiotic metabolism. The gut microbiome, the collection of microorganisms in the gastrointestinal tract, can alter the metabolic outcome of pharmaceuticals, environmental toxic
Autor:
Kyoung Heon Kim, Robert Riley, Aditi Sharma, Jenifer Johnson, Bernard Henrissat, Byoungnam Min, In Geol Choi, Joseph W. Spatafora, Igor V. Grigoriev, Jungyeon Kim, Jae Jin Kim, Yeongseon Jang, Bill Andreopoulos, Hongjae Park, Anna Lipzen
Publikováno v:
Applied microbiology and biotechnology, vol 103, iss 19
Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology, Springer Verlag, 2019, 103 (19), pp.8145-8155. ⟨10.1007/s00253-019-10089-6⟩
Applied Microbiology and Biotechnology, 2019, 103 (19), pp.8145-8155. ⟨10.1007/s00253-019-10089-6⟩
Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology, Springer Verlag, 2019, 103 (19), pp.8145-8155. ⟨10.1007/s00253-019-10089-6⟩
Applied Microbiology and Biotechnology, 2019, 103 (19), pp.8145-8155. ⟨10.1007/s00253-019-10089-6⟩
International audience; The environmental accumulation of polycyclic aromatic hydrocarbons (PAHs) is of great concern due to potential carcinogenic and mutagenic risks, as well as their resistance to remediation. While many fungi have been reported t
Publikováno v:
Journal of Investigative Dermatology, 141, 1385-1388
J Invest Dermatol
Journal of Investigative Dermatology, 141, 6, pp. 1385-1388
The Journal of Investigative Dermatology
J Invest Dermatol
Journal of Investigative Dermatology, 141, 6, pp. 1385-1388
The Journal of Investigative Dermatology
The AHR is an environmental sensor and transcription factor activated by a variety of man-made and natural ligands, which has recently emerged as a critical regulator of homeostasis at barrier organs such as the skin. Activation of the AHR pathway do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ec4ac259cb9853b4b1e19ec05af4e6
http://hdl.handle.net/2066/235349
http://hdl.handle.net/2066/235349
Autor:
Katharina Kohse-Höinghaus
Publikováno v:
Proceedings of the Combustion Institute. International Symposium on Combustion
Combustion involves chemical reactions that are often highly exothermic. Combustion systems utilize the energy of chemical compounds released during this reactive process for transportation, to generate electric power, or to provide heat for various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3000cde68ef341028ddd5bf5624c989
https://doi.org/10.1016/j.proci.2020.06.375
https://doi.org/10.1016/j.proci.2020.06.375
Autor:
Guy N'da, Josefo Ferro, Anne Korir, Henry Wabinga, H. Nouhou, Liacine Bouaoun, Charles Gombé Mbalawa, Joachim Schüz, Valerie McCormack, Steady Chasimpha, Margaret Borok, Charles Dzamalala, Eric Chokunonga, Moussa Koulibaly, Daniel R. S. Middleton, Femi Ogunbiyi, Diana Menya, Amos Mwasamwaja, Freddie Bray, Blandina T. Mmbaga, Nathan Buziba, Rachel Hanisch, Ramou Njie, Mathewos Assefa Woldegeorgis
Publikováno v:
Cancer Epidemiology
Highlights • We conducted a review and meta-analysis of esophageal cancer sex ratios in mainland Africa using data from 197 populations in 36 countries. • We observed a consistent male excess in incidence rates overall and in the high-risk Easter
Autor:
Stiborová, Marie, Dračínská, Helena, Bořek-Dohalská, Lucie, Klusoňová, Zuzana, Holecová, Jana, Martínková, Markéta, Schmeiser, Heinz H., Arlt, Volker M.
Publikováno v:
Toxicology
Graphical abstract Effects of 17α-ethinylestradiol (EE2) and estradiol (ESTRA) on DNA adducts formed by benzo[a]pyrene (BaP).
Highlights • 17α-ethinylestradiol (EE2) and estradiol affect genotoxicity of benzo[a]pyrene (BaP) in rats. • Cyto
Highlights • 17α-ethinylestradiol (EE2) and estradiol affect genotoxicity of benzo[a]pyrene (BaP) in rats. • Cyto
Publikováno v:
Toxicology Reports
Highlights • The half-life of BaP is 3–4 days and then it metabolized in the liver. • BaP concentration in the muscle of treated fish reached a maximum level after 4 days. • Exposure of fish to BaP resulted in a decrease in T3 and T4 plasma l
Autor:
Alexandra J, Willis, Radek, Indra, Laura E, Wohak, Osman, Sozeri, Kerstin, Feser, Iveta, Mrizova, David H, Phillips, Marie, Stiborova, Volker M, Arlt
Publikováno v:
Toxicology
Polycyclic aromatic hydrocarbons such as benzo[a]pyrene (BaP) can induce cytochrome P450 1A1 (CYP1A1) via a p53-dependent mechanism. The effect of different p53-activating chemotherapeutic drugs on CYP1A1 expression, and the resultant effect on BaP m
Autor:
Robinson, Ryan K., Birrell, Mark A., Adcock, John J., Wortley, Michael A., Dubuis, Eric D., Chen, Shu, McGilvery, Catriona M., Hu, Sheng, Shaffer, Milo S.P., Bonvini, Sara J., Maher, Sarah A., Mudway, Ian S., Porter, Alexandra E., Carlsten, Chris, Tetley, Teresa D., Belvisi, Maria G.
Publikováno v:
Robinson, R K, Birrell, M A, Adcock, J J, Wortley, M A, Dubuis, E D, Chen, S, McGilvery, C M, Hu, S, Shaffer, M SP, Bonvini, S J, Maher, S A, Mudway, I S, Porter, A E, Carlsten, C, Tetley, T D & Belvisi, M G 2017, ' Mechanistic Link between Diesel Exhaust Particles and Respiratory Reflexes ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2017.04.038
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
Background Diesel exhaust particles (DEPs) are a major component of particulate matter in Europe's largest cities, and epidemiologic evidence links exposure with respiratory symptoms and asthma exacerbations. Respiratory reflexes are responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::70852a4578f0cb5b4cbf10838396cb44
http://hdl.handle.net/10044/1/48400
http://hdl.handle.net/10044/1/48400
Autor:
Per E. Schwarze, Anita Solhaug, Kristine B. Gutzkow, Jørn A. Holme, Leni Ekeren, Volker M. Arlt, Anika Bhargava, Hannah E. Nyvold, Victor Tat, Rune Becher, Marit Låg, Kjetil Ask, Johan Øvrevik
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 1, Iss C, Pp 459-473 (2014)
Toxicology Reports, Vol 1, Iss C, Pp 459-473 (2014)
This study explores and characterizes the toxicity of two closely related carcinogenic dinitro-pyrenes (DNPs), 1,3-DNP and 1,8-DNP, in human bronchial epithelial BEAS-2B cells and mouse hepatoma Hepa1c1c7 cells. Neither 1,3-DNP nor 1,8-DNP (3–30 μ