Zobrazeno 1 - 2
of 2
pro vyhledávání: '"PAH, paired amphipathic helix"'
Autor:
Rama Kadamb, Boris A Leibovitch, Eduardo F Farias, Nisha Dahiya, Hemant Suryawanshi, Nidhi Bansal, Samuel Waxman
Publikováno v:
Translational Oncology, Vol 16, Iss, Pp 101320-(2022)
Translational Oncology
Translational Oncology
Highlights • We show that the PAH2 domain of SIN3A is a target when it is inhibited from binding to PF1 results in inhibition of invasive phenotype in TNBC. • Epigenetic repression of integrins expression and downstream pathways results from enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bca11981746da3037e321adcd48f7a
https://doi.org/10.1016/j.tranon.2021.101320
https://doi.org/10.1016/j.tranon.2021.101320
Autor:
Rasmus Greve Falbe-Hansen, Birthe B. Kragelund, Lasse Staby, Karen Skriver, Katrine Bugge, Edoardo Salladini
Publikováno v:
The Journal of Biological Chemistry
Bugge, K, Staby, L, Salladini, E, Falbe-Hansen, R G, Kragelund, B B & Skriver, K 2021, ' αα-Hub domains and intrinsically disordered proteins : a decisive combo ', Journal of Biological Chemistry, vol. 296, 100226 . https://doi.org/10.1074/jbc.REV120.012928
Bugge, K, Staby, L, Salladini, E, Falbe-Hansen, R G, Kragelund, B B & Skriver, K 2021, ' αα-Hub domains and intrinsically disordered proteins : a decisive combo ', Journal of Biological Chemistry, vol. 296, 100226 . https://doi.org/10.1074/jbc.REV120.012928
Hub proteins are central nodes in protein-protein interaction networks with critical importance to all living organisms. Recently, a new group of folded hub domains, the αα-hubs, was defined based on a shared αα-hairpin super-secondary structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87883cc51fb011ae4f4fcf80987e026
https://doi.org/10.1074/jbc.rev120.012928
https://doi.org/10.1074/jbc.rev120.012928