Asthmatic Bronchial Epithelial Cells (BEC) do not undergo apoptosis in response to Rhinovirus (RV) infection and this is associated with increased viral replication

Autor: PAB WARK, S. PUDDICOMBE, AL ANDREWS, SL JOHNSTON, ST HOLGATE, DE DAVIES, BUCCHIERI, Fabio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e26c3ae8df1be1758107c3330feb17eb
http://hdl.handle.net/10447/2608

Inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma.

Autor: Chen L; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., A Hoefel G; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Pathinayake PS; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Reid A; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Pillar AL; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Kelly C; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Tan H; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Ali A; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Kim RY; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia.; School of Life Sciences, University of Technology Sydney, Sydney, New South Wales, Australia., Hansbro PM; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Faculty of Science, School of Life Sciences, Sydney, New South Wales, Australia., Brody SL; Department of Medicine, Washington University School of Medicine in St Louis, St Louis, Missouri, USA., Foster PS; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Horvat JC; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Riveros C; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia., Awatade N; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Wark PAB; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, New Lambton, New South Wales, Australia.; Department of Respiratory Medicine, Alfred Health, Melbourne, Victoria, Australia., Kaiko GE; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Immune Health Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia.

Publikováno v: Respirology (Carlton, Vic.) [Respirology] 2025 Jan; Vol. 30 (1), pp. 25-40. Date of Electronic Publication: 2024 Oct 02.

Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthma.

Autor: Khaleva E; Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK doctor.khaleva@gmail.com.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Brightling C; Institute for Lung Health, Leicester NIHR BRC, University of Leicester, UK., Eiwegger T; Karl Landsteiner University of Health Sciences, Krems, Austria.; Translational Medicine Program, Research Institute, The Hospital for Sick Children, Toronto, Canada.; Department of Immunology, University of Toronto, Toronto, Canada.; Department of Pediatric and Adolescent Medicine, University Hospital St. Pölten, St. Pölten, Austria., Altraja A; Department of Pulmonology, University of Tartu and Lung Clinic, Tartu University Hospital, Tartu, Estonia., Bégin P; Department of Medicine, CHUM, Montréal. 2. Department of Pediatrics, CHU Ste-Justine, Montréal., Blumchen K; Department of Children and Adolescent Medicine, Division of Pneumology, Allergology and Cystic fibrosis, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany., Bossios A; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge, Sweden.; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Bourdin A; PhyMedExp, University of Montpellier, Montpellier, France., Ten Brinke A; Department of Respiratory Medicine, Medical Centre Leeuwarden, Leeuwarden, the Netherlands., Brusselle G; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Silvia Bumbacea R; Department of Allergology 'Carol Davila', University of Medicine and Pharmacy, Bucharest, Romania, Department of Allergology 'Dr. Carol Davila' Nephrology Clinical Hospital, Bucharest, Romania., Bush A; Centre for Paediatrics and Child Health and National Heart and Lung Institute, Imperial College; Royal Brompton Hospital, London, UK., Casale TB; Division of Allergy/Immunology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA., Clarke GW; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals, R&D, AstraZeneca.; School of Immunology & Microbial Sciences, King's College London, London, UK., Chaudhuri R; School of Infection & Immunity, University of Glasgow, Glasgow, UK., Fan Chung K; National Heart & Lung Institute, Imperial College London, London, UK., Coleman C; European Lung Foundation, Sheffield, UK., Corren J; David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Dahlén SE; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Deschildre A; Univ Lille, CHU Lille, Unité de Pneumologie et Allergologie Pédiatrique, Hôpital Jeanne de Flandre F-59000 Lille, France.; U1019 - UMR 8204 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Djukanovic R; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Eger K; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Exley A; Adept Biologica Consulting Limited, London, UK., Fleming L; National Heart and Lung Institute, Imperial College, London., Fowler SJ; Faculty of Biology, Medicine and Health, School of Biological Sciences, Division of Infection, Immunity & Respiratory Medicine, The University of Manchester, and NIHR Manchester Biomedical Research Unit and Manchester University NHS Foundation Trust, Manchester, UK., Gaillard EA; University of Leicester, Department of Respiratory Sciences, Leicester NIHR Biomedical Research Centre (Respiratory theme), Leicester, UK., Gappa M; Department of Pediatrics, Evangelisches Krankenhaus Düsseldorf, Düsseldorf, Germany., Gupta A; Department of Paediatric Respiratory Medicine, King's College Hospital, London, UK., Michael Haitchi H; Respiratory Medicine Department, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.; Institute for Life Sciences, University of Southampton, Southampton, United Kingdom., Hashimoto S; Department of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Heaney LG; Wellcome-Wolfson Centre for Experimental Medicine School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, UK., Hedlin G; Department of Women's and Children's Health and Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Henderson M; European Federation of Allergy and Airways Diseases Patients' Associations, Brussels, Belgium., Hua W; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, , China., Jackson DJ; King's Centre for Lung Health, King's College London.; Guy's Asthma Centre, Guy's & St Thomas' NHS Trust, London, UK., Karadag B; Marmara University Faculty of Medicine, Division of Pediatric Pulmonology, Istanbul, Turkey., Helen Katelaris C; Immunology and Allergy Unit Campbelltown Hospital and Western Sydney University Campbelltown, Sydney, Australia., Koh MS; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.; Duke- National University Singapore, Singapore., Volkmar Kopp M; University Children's Hospital of Bern, Inselspital, University of Bern, Bern, Switzerland.; Airway Research Center North (ARCN), German Center for Lung Research (DZL), Luebeck, Germany., Koppelman GH; University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, the Netherlands., Kull I; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Kurukulaaratchy RJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton.; David Hide Asthma & Allergy Centre, St Mary's Hospital, Newport, Isle of Wight., Lee JH; Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Mahler V; Paul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines, Division of Allergology, Langen, Germany., Mäkelä M; HUS Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Masoli M; University of Exeter, Royal Devon and Exeter Hospital, Exeter, United Kingdom., Mathioudakis AG; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, UK.; North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Mazon A; Unit of Pediatric Allergy and Pneumology, Health Research Institute La Fe, University and Polytechnic Hospital La Fe, Valencia, Spain., Melén E; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Milger K; Department of Medicine V, University Hospital, LMU Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL)., Moeller A; Department of Respiratory Medicine, University Children's Hospital Zurich and Childhood Research Center, Zurich, Switzerland., Murray CS; Faculty of Biology, Medicine and Health, School of Biological Sciences, Division of Infection, Immunity and Respiratory Medicine, University of Manchester, NIHR Manchester Biomedical Research Unit, Manchester University NHS Foundation Trust, Manchester, UK., Nagakumar P; Department of Respiratory Medicine, Birmingham Children's Hospital, Steelhouse lane, Birmingham, UK.; Institute of Inflammation and Ageing, University of Birmingham., Nair P; Department of Medicine, Division of Respirology, St Joseph's Healthcare & McMaster University, Hamilton, Ontario, Canada., Negus J; 3TR respiratory working group, Brussels, Belgium., Nieto A; Pediatric Pulmonology & Allergy Unit, Health Reasearch Institute, Hospital la Fe, Valencia, Spain., Papadopoulos NG; Allergy Dpt, 2nd Pediatric Clinic, University of Athens, Athens, Greece.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Paton J; School of Medicine, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, UK., Pijnenburg MW; Erasmus MC - Sophia Children's Hospital, University Medical Centre Rotterdam, Department of Paediatrics/ Paediatric Respiratory Medicine and Allergology, Rotterdam, The Netherlands., Pike KC; Department of Paediatric Respiratory Medicine, Bristol Royal Hospital for Children, Bristol, UK., Porsbjerg C; Department of Respiratory Medicine, Respiratory Research Unit, Bispebjerg Hospital, Copenhagen, Denmark., Rattu A; Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Rupani H; Department of Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Rusconi F; Department of Mother and Child Health, Azienda USL Toscana Nord Ovest, Pisa, Italy., Rutjes NW; Department of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands., Saglani S; National Heart and Lung Institute, Imperial College London, UK., Seddon P; Respiratory Care, Royal Alexandra Children's Hospital, Brighton, UK., Siddiqui S; Imperial NIHR Biomedical Research Centre, National Lung and Heart Institute, Imperial College London, London, UK., Singer F; Department of Respiratory Medicine, University Children's Hospital Zurich and Childhood Research Center, Zurich, Switzerland.; Division of Paediatric Pulmonology and Allergology, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Austria., Tajiri T; Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University School of Medical Sciences, Nagoya, Japan., Turner S; Women and children division, NHS Grampian, Aberdeen, UK; 2. Child Health, University of Aberdeen, Aberdeen, UK., Upham JW; Frazer Institute, The University of Queensland.; Princess Alexandra Hospital, Brisbane, Australia., Vijverberg SJH; Department of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.; Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Wark PAB; School of Translational Medicine, Monash University., Wechsler ME; NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, CO., Yasinska V; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge and Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden., Roberts G; Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; NIHR Southampton Biomedical Research Centre, University Hospital Foundation Trust, Southampton, UK.

Publikováno v: The European respiratory journal [Eur Respir J] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.

Large airway wall vascularity in patients with asthma-COPD overlap: a bronchoscopy study.

Autor: Dey S; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia., Lu W; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Launceston Respiratory and Sleep Centre, Launceston, Australia., Weber HC; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Department of Respiratory Medicine, Tasmanian Health Services, North-West Hospital, Burnie, Australia., Chia C; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Launceston Respiratory and Sleep Centre, Launceston, Australia.; Department of Respiratory Medicine, Launceston General Hospital, Launceston, Australia., Pathinayake PS; Immune Health Program, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia., Wark PAB; Immune Health Program, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia.; Department of Respiratory Medicine, Monash University, Melbourne, Australia., Eapen MS; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia., Sohal SS; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Launceston Respiratory and Sleep Centre, Launceston, Australia.

Publikováno v: ERJ open research [ERJ Open Res] 2024 Jul 08; Vol. 10 (4). Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024).

Faecal microbial transfer and complex carbohydrates mediate protection against COPD.

Autor: Budden KF; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Shukla SD; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Bowerman KL; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, The University of Queensland, Brisbane, QLD, Australia., Vaughan A; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.; UQ Thoracic Research Centre, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Department of Thoracic Medicine, The Prince Charles Hospital, Chermside, QLD, Australia., Gellatly SL; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Wood DLA; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, The University of Queensland, Brisbane, QLD, Australia., Lachner N; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, The University of Queensland, Brisbane, QLD, Australia., Idrees S; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Rehman SF; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia.; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Faiz A; Respiratory Bioinformatics and Molecular Biology, School of Life Sciences, University of Technology Sydney, Sydney, NSW, Australia., Patel VK; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Donovan C; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Alemao CA; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Shen S; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Amorim N; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Majumder R; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Vanka KS; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Mason J; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Haw TJ; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Tillet B; Frazer Institute, University of Queensland, Woolloongabba, QLD, Australia., Fricker M; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Keely S; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Hansbro N; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Belz GT; Frazer Institute, University of Queensland, Woolloongabba, QLD, Australia., Horvat J; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Ashhurst T; Sydney Cytometry, Charles Perkins Centre, Centenary Institute and The University of Sydney, Sydney, NSW, Australia.; Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, NSW, Australia., van Vreden C; Sydney Cytometry, Charles Perkins Centre, Centenary Institute and The University of Sydney, Sydney, NSW, Australia.; Ramaciotti Facility for Human Systems Biology, Charles Perkins Centre and The University of Sydney, Sydney, NSW, Australia., McGuire H; Ramaciotti Facility for Human Systems Biology, Charles Perkins Centre and The University of Sydney, Sydney, NSW, Australia., Fazekas de St Groth B; Ramaciotti Facility for Human Systems Biology, Charles Perkins Centre and The University of Sydney, Sydney, NSW, Australia., King NJC; Sydney Cytometry, Charles Perkins Centre, Centenary Institute and The University of Sydney, Sydney, NSW, Australia.; Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, NSW, Australia.; Ramaciotti Facility for Human Systems Biology, Charles Perkins Centre and The University of Sydney, Sydney, NSW, Australia.; Discipline of Pathology, Faculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Sydney, NSW, Australia., Crossett B; Sydney Mass Spectrometry, The University of Sydney, Sydney, NSW, Australia., Cordwell SJ; Sydney Mass Spectrometry, The University of Sydney, Sydney, NSW, Australia.; School of Life and Environmental Sciences, Charles Perkins Centre and The University of Sydney, Sydney, NSW, Australia., Bonaguro L; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Schultze JL; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Hamilton-Williams EE; Frazer Institute, University of Queensland, Woolloongabba, QLD, Australia., Mann E; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Forster SC; Centre for Innate Immunity and Infectious Diseases and Department of Molecular and Translational Science, Hudson Institute of Medical Research and Monash University, Melbourne, VIC, Australia., Cooper MA; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Segal LN; Division of Pulmonary and Critical Care Medicine, Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, NY, USA., Chotirmall SH; Lee Kong Chian School of Medicine, Translational Respiratory Research Laboratory, Singapore., Collins P; Mater Research Institute, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; Department of Dietetics & Food Services, Mater Hospital, Brisbane, QLD, Australia., Bowman R; UQ Thoracic Research Centre, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Department of Thoracic Medicine, The Prince Charles Hospital, Chermside, QLD, Australia., Fong KM; UQ Thoracic Research Centre, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Department of Thoracic Medicine, The Prince Charles Hospital, Chermside, QLD, Australia., Yang IA; UQ Thoracic Research Centre, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Department of Thoracic Medicine, The Prince Charles Hospital, Chermside, QLD, Australia., Wark PAB; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia., Dennis PG; School of Earth and Environmental Sciences, The University of Queensland, Brisbane, QLD, Australia., Hugenholtz P; School of Chemistry and Molecular Biosciences, Australian Centre for Ecogenomics, The University of Queensland, Brisbane, QLD, Australia., Hansbro PM; Priority Research Centre for Healthy Lungs and Immune Health Research Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia Philip.Hansbro@uts.edu.au.; Centre for Inflammation, Centenary Institute, Sydney, NSW, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.

Publikováno v: Gut [Gut] 2024 Apr 05; Vol. 73 (5), pp. 751-769. Date of Electronic Publication: 2024 Apr 05.