Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma

Autor: MI Rosenberg, E Greenstein, M Buchkovich, M Mikl, A Peres, E Santoni-Rugiu, D Reshef, A Salovin, DL Gibbs, MS Irwin, A Naranjo, I Ulitsky, PA de Alarcon, V Weigman, G Yaari, JA Panzer, N Friedman, JM Maris

SummaryNeuroblastoma is a lethal childhood solid tumor of developing peripheral nerves. Two percent of children with neuroblastoma develop Opsoclonus Myoclonus Ataxia Syndrome (OMAS), a paraneoplastic disease characterized by cerebellar and brainstem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c14aa2a979a20ce12a67a3c7a8280b8f
https://doi.org/10.1101/2021.12.14.471886

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Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma.

Autor: Rosenberg MI; Hebrew University of Jerusalem, Edmond Safra Campus, Givat Ram, Jerusalem 91904, Israel. Electronic address: miriamirosenberg@gmail.com., Greenstein E; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Buchkovich M; Q2 Solutions, Durham, NC, USA., Peres A; Bio-engineering, Faculty of Engineering, Bar Ilan University, Ramat Gan, Israel; Bar Ilan Institute of Nanotechnologies and Advanced Materials, Bar Ilan University, Ramat Gan, Israel., Santoni-Rugiu E; Department of Pathology, Rigshospitalet, Copenhagen University Hospital and Department of Clinical Medicine, University of Copenhagen, 2100 Copenhagen, Denmark., Yang L; Pacific Northwest Research Institute, Seattle, WA 98122, USA., Mikl M; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Mount Carmel, Haifa 31905, Israel., Vaksman Z; New York Genome Center, New York, NY 10013, USA., Gibbs DL; Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA 98109, USA., Reshef D; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Salovin A; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Irwin MS; Department of Pediatrics and Division of Hematology-Oncology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G1X8, Canada., Naranjo A; Department of Biostatistics, University of Florida, Children's Oncology Group Statistics & Data Center, Gainesville, FL, USA., Ulitsky I; Department of Immunology & Regenerative Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., de Alarcon PA; Department of Pediatrics, Hematology/Oncology, University of Illinois College of Medicine Peoria, Peoria, IL 61605, USA., Matthay KK; Department of Pediatrics, UCSF School of Medicine, San Francisco, CA 94143, USA., Weigman V; Q2 Solutions, Durham, NC, USA., Yaari G; Bio-engineering, Faculty of Engineering, Bar Ilan University, Ramat Gan, Israel; Bar Ilan Institute of Nanotechnologies and Advanced Materials, Bar Ilan University, Ramat Gan, Israel., Panzer JA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Friedman N; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Maris JM; Department of Pediatrics and Division of Oncology, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: maris@chop.edu.

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