Zobrazeno 1 - 10
of 36
pro vyhledávání: '"PA, Palmitic Acid"'
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 436-442 (2021)
Toxicology Reports, Vol 8, Iss, Pp 436-442 (2021)
Graphical abstract
Highlights • 3-Monochloropropane-1,2-diol (3-MCPD) and its fatty acid esters have the potential to induce nephrotoxicity. • We used an in vitro cellular model of human proximal tubule cells to test the effects of 3-MCPD co
Highlights • 3-Monochloropropane-1,2-diol (3-MCPD) and its fatty acid esters have the potential to induce nephrotoxicity. • We used an in vitro cellular model of human proximal tubule cells to test the effects of 3-MCPD co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43f02172ae4554851ba7cd5ec28173d
http://europepmc.org/articles/PMC7932896
http://europepmc.org/articles/PMC7932896
Autor:
Menghao Huang, Kushan Chowdhury, Zhigang Fang, X. Charlie Dong, Ming O. Li, Suthat Liangpunsakul, Hyeong-Geug Kim
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Sestrin 1/2/3 (Sesn1/2/3) belong to a small family of proteins that have been implicated in the regulation of metabolic homeostasis and oxidative stress. However, the underlying mechanisms remain incompletely understood. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574bc0f082fa7f7fd23bf88f6f9c6fc
http://www.sciencedirect.com/science/article/pii/S2352345X21000862
http://www.sciencedirect.com/science/article/pii/S2352345X21000862
Publikováno v:
JID Innovations, Vol 2, Iss 1, Pp 100064-(2022)
JID Innovations
JID Innovations
Obesity is a growing epidemic worldwide, and it is also considered a major environmental factor contributing to the pathogenesis of inflammatory skin diseases, including psoriasis (PSO) and atopic dermatitis (AD). Moreover, obesity worsens the course
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cacaa551132dbadfca2113955e3e55
http://www.sciencedirect.com/science/article/pii/S2667026721000655
http://www.sciencedirect.com/science/article/pii/S2667026721000655
Autor:
Marlena C. Kruger, Frances M. Wolber, Hong (Sabrina) Tian, Matthew R. Miller, Parkpoom Siriarchavatana
Publikováno v:
Bone Reports
Bone Reports, Vol 15, Iss, Pp 101132-(2021)
Bone Reports, Vol 15, Iss, Pp 101132-(2021)
The osteoclast-dependent bone resorption process is a crucial part of the bone regulatory system. The excessive function of osteoclasts can cause diseases of bone, joint, and other tissues such as osteoporosis and osteoarthritis. Greenshell mussel oi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804982a1fe1106d3242e9a1f1ddc0d62
http://europepmc.org/articles/PMC8493498
http://europepmc.org/articles/PMC8493498
Autor:
Nesrin Kartal Ozer, Tugce Demirel-Yalciner, Ceren Avcilar, Tuna Felix Samanci, Dyana Sari, Erdi Sozen
Publikováno v:
Metabolism Open
Metabolism Open, Vol 12, Iss, Pp 100138-(2021)
Metabolism Open, Vol 12, Iss, Pp 100138-(2021)
Objective Increased fatty acid and triglyceride synthesis in liver, majorly modulated by Sterol Regulator Elementing Binding Protein 1c (SREBP1c), is one of the main features of non-alcoholic fatty liver disease (NAFLD). In the present study, we aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4eac64c79cf8a24a6a6c574d5fc176f
https://pubmed.ncbi.nlm.nih.gov/34704008
https://pubmed.ncbi.nlm.nih.gov/34704008
Autor:
Geraldine Leman, Gregor Oemer, Sandrine Dubrac, Yvonne Wohlfarter, Markus A. Keller, Jakob Koch, Marie-Luise Edenhofer, Herbert Lindner, Johannes Zschocke, Luiza Helena Daltro Cardoso, Katharina Lackner, Erich Gnaiger
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100111-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100111-(2021)
The molecular assembly of cells depends not only on the balance between anabolism and catabolism but to a large degree on the building blocks available in the environment. For cultured mammalian cells, this is largely determined by the composition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b905318fb7d5ca2f24bc394337f45d5
http://europepmc.org/articles/PMC8455370
http://europepmc.org/articles/PMC8455370
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 745-757 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Non-alcoholic steatohepatitis (NASH) is a chronic metabolic syndrome and the CFLAR-JNK pathway can reverse the process of NASH. Although silibinin is used for the treatment of NASH in clinical, its effect on CFLAR-JNK pathway in NASH remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e7ccc826a7d00426fc07ff24e9b917
https://doi.org/10.1016/j.apsb.2019.02.006
https://doi.org/10.1016/j.apsb.2019.02.006
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 61-73 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Protein kinase C (PKC) has critical roles in regulating lipid anabolism and catabolism. PKCζ, a member of atypical PKC family, has been reported to mediate glucose metabolism. However, whether and how PKCζ regulates tumor cells fatty acid β-oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde2c0d4365d58fb67f1dc31a10dc718
http://www.sciencedirect.com/science/article/pii/S1476558618303130
http://www.sciencedirect.com/science/article/pii/S1476558618303130
Autor:
Zhanxiang Zhou, Wei Zhong, Liuyi Hao, Haibo Dong, Tianjiao Li, Ruichao Yue, Wei Guo, Xinguo Sun
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1599-1615 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1599-1615 (2021)
Background & Aims Alcohol-related liver disease (ALD) is characterized by accumulation of hepatic free fatty acids (FFAs) and triglyceride (TG)-enriched lipid droplets and cell death. The present study aimed to investigate how FFA or TG induces hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4253198fff334c86b673433fdff4237
https://pubmed.ncbi.nlm.nih.gov/34284164
https://pubmed.ncbi.nlm.nih.gov/34284164
Autor:
Lei Qian, Xinya Xie, Xin Nie, Nanping Wang, Erjiao Qiang, Jingyang Zhao, Wenfei Zhao, Zihui Zhang, Lei Xiao, Weiqi Tang, Chunmiao Yang
Publikováno v:
Redox Biology, Vol 37, Iss, Pp 101728-(2020)
Redox Biology
Redox Biology
Hyperglycemia-induced endothelial endoplasmic reticulum (ER) stress is implicated in the pathophysiology of diabetes and its vascular complications. Procyanidins are enriched in many plant foods and have been demonstrated to exert several beneficial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf0e03aa4920fa7a39d220fc5443287
http://www.sciencedirect.com/science/article/pii/S2213231720309332
http://www.sciencedirect.com/science/article/pii/S2213231720309332