Zobrazeno 1 - 10
of 1 731
pro vyhledávání: '"P53 PATHWAY"'
Autor:
Hao Wenbo, Lin Fei, Kong Weili, Shi Hanbing, Dong Haiying, Guan Zhanjiang, Liu Guohua, Wang Xiao, Wang Li, Liu Moran, Jiang Yunfei
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 6924-65 (2024)
This study investigated the role and mechanisms of cullin-1 (CUL1) in chronic obstructive pulmonary disease (COPD).
Externí odkaz:
https://doaj.org/article/fcc2209998ce4e6aaf12928beefee081
Autor:
Mohammad Yasin Zamanian, Niloofar Taheri, Montather F. Ramadan, Yasser Fakri Mustafa, Safa Alkhayyat, Klunko Nataliya Sergeevna, Hashem O. Alsaab, Ahmed Hjazi, Farnoosh Molavi Vasei, Siamak Daneshvar
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 5, Pp 591-605 (2024)
Abstract Flavonoids, including fisetin, have been linked to a reduced risk of colorectal cancer (CRC) and have potential therapeutic applications for the condition. Fisetin, a natural flavonoid found in various fruits and vegetables, has shown promis
Externí odkaz:
https://doaj.org/article/91c8f028541f4787823039d06a9b3ade
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 4093-4104 (2024)
Shiyu Wang,1– 4 Wei Qin,1– 4 Tingting Cheng,1– 4 Cong Zeng,1– 4 Xu Chen,1– 4 Yajing Xu1– 4 1Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2National Clinical Research C
Externí odkaz:
https://doaj.org/article/e60d838096ce42a38fd263622e21a986
Publikováno v:
PeerJ, Vol 12, p e17933 (2024)
LncRNA is a type of transcript with a length exceeding 200 nucleotides, which was once considered junk transcript with no biological function during the transcription process. In recent years, lncRNA has been shown to act as an important regulatory f
Externí odkaz:
https://doaj.org/article/807539d167304e50a520ee747375d8dc
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Cyclin B2 (CCNB2), a member of the cyclin family, is an oncogene in multiple cancers, including nasopharyngeal carcinoma (NPC). However, the epigenetics mechanism for CCNB2 overexpression in NPC remains unclear. This study dissect
Externí odkaz:
https://doaj.org/article/36158c6f41ff401f8b615ea58b83a2e8
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 10, Pp 1604-1607 (2023)
Glioma is the most common primary tumor found in central nervous system of adult patients. The forkhead box protein M1 (FOXM1) is a member of the forkhead box transcription factor family, which can regulate Wnt/β-Catenin, Akt/FOXM1, p53 pathways and
Externí odkaz:
https://doaj.org/article/5d777c296fb9434e99adb084951c2d98
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-25 (2023)
Abstract Background TP53 is a master tumor suppressor gene, mutated in approximately half of all human cancers. Given the many regulatory roles of the corresponding p53 protein, it is possible to infer loss of p53 activity – which may occur due to
Externí odkaz:
https://doaj.org/article/0e83e71c9c774af0b871e2049e79e55c
Autor:
Zhen-Fei Zhang, Fang Liu, Han-Rong Zhang, Bing Liu, Shu-Qian Zheng, Wan-Qian Ye, Jia-Nan Ding, Ze-Jie Zhou, Hui-Xian Luo, Fang Wu, Xuan-Min Guo, Jue-Yu Zhou, Yong-Hui Guo
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Objective Recent studies indicated that transmembrane protein 40 (TMEM40) is associated with several types of cancers but is not clear in cervical cancer (CC). The study aimed to examine the role of TMEM40 in CC and related mechanisms. Metho
Externí odkaz:
https://doaj.org/article/382d5425a0d042c7b8964f5dfd15c524
Autor:
Manisha Singh, Divya Jindal, Vinayak Agarwal, Deepanshi Pathak, Mansi Sharma, Pranav Pancham, Shalini Mani, Rachana
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 8, Pp 867-889 (2022)
Glioblastoma multiforme (GBM) is known as the most aggressive and prevalent brain tumor with a high mortality rate. It is reported in people who are as young as 10 years old to as old as over 70 years old, exhibiting inter and intra tumor heterogenei
Externí odkaz:
https://doaj.org/article/f051c1a0f7424afdb544ea54a5d9251d
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