Zobrazeno 1 - 10
of 972
pro vyhledávání: '"P2Y receptors"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
This review outlined evidence that purinergic signaling is involved in the modulation of blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is critical for maintaining the homeostasis of the brain microenvironm
Externí odkaz:
https://doaj.org/article/ca9f6dfd784248dba10f418cea1e5207
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Adipose tissue is a source of stem cells with a high potential of differentiation for cell-based regenerative therapies. We previously identified mouse P2Y2, an ATP and UTP nucleotide receptor, as a regulator of adipogenic and endothelial differentia
Externí odkaz:
https://doaj.org/article/258f1393942e4101a65d15862bd2b6c3
Autor:
Srdjan M. Vlajkovic, Peter R. Thorne
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14874 (2022)
The mammalian cochlea is the sensory organ of hearing with a delicate, highly organised structure that supports unique operating mechanisms. ATP release from the secretory tissues of the cochlear lateral wall (stria vascularis) triggers numerous phys
Externí odkaz:
https://doaj.org/article/5355bdb490724cb5b799863c837cfc3d
Microglial cells, the resident macrophages of the central nervous system (CNS), exist in a process-bearing, ramified/surveying phenotype under resting conditions. Upon activation by cell-damaging factors, they get transformed into an amoeboid phenoty
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A84734
https://ul.qucosa.de/api/qucosa%3A84734/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A84734/attachment/ATT-0/
Akademický článek
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Publikováno v:
Life, Vol 11, Iss 11, p 1170 (2021)
Extracellular ATP in the tumor microenvironment exhibits either pro- or antitumor effect via interaction with P2Y receptors, but the intracellular signaling and functional roles of P2Y receptors in oral squamous cell carcinoma (OSCC) are unclear. We
Externí odkaz:
https://doaj.org/article/ff61f319a17142b095effa1ebf562787
Autor:
Sun-Hee Woo, Tran Nguyet Trinh
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 251 (2020)
ATP is a major energy source in the mammalian cells, but it is an extracellular chemical messenger acting on P2 purinergic receptors. A line of evidence has shown that ATP is released from many different types of cells including neurons, endothelial
Externí odkaz:
https://doaj.org/article/595fd059af54482e8e02980c32732f2c
Autor:
Derek Strassheim, Alexander Verin, Robert Batori, Hala Nijmeh, Nana Burns, Anita Kovacs-Kasa, Nagavedi S. Umapathy, Janavi Kotamarthi, Yash S. Gokhale, Vijaya Karoor, Kurt R. Stenmark, Evgenia Gerasimovskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6855 (2020)
Purinergic G-protein-coupled receptors are ancient and the most abundant group of G-protein-coupled receptors (GPCRs). The wide distribution of purinergic receptors in the cardiovascular system, together with the expression of multiple receptor subty
Externí odkaz:
https://doaj.org/article/1af3d05d3efe406683092f959e2819d2
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5227 (2020)
The migration of chondrocytes from healthy to injured tissues is one of the most important challenges during cartilage repair. Additionally, maintenance of the chondrogenic phenotype remains another limitation, especially during monolayer culture in
Externí odkaz:
https://doaj.org/article/a33dbd1ba4224123a45d4ed7edede2ed
Publikováno v:
Cells, Vol 9, Iss 5, p 1108 (2020)
Microglial cells, the resident macrophages of the central nervous system (CNS), exist in a process-bearing, ramified/surveying phenotype under resting conditions. Upon activation by cell-damaging factors, they get transformed into an amoeboid phenoty
Externí odkaz:
https://doaj.org/article/c010b1c69de24eb6a18be4d63e19dba8