Should We Use Aspirin or P2Y 12 Inhibitor Monotherapy in Stable Ischemic Heart Disease?

Autor: Chandiramani R; 600 N Wolfe St sted 560, Baltimore, MD, 21287, USA., Mehta A; Department of Internal Medicine, Albert Einstein College of Medicine/Jacobi Medical Center, Bronx, NY, USA., Blumenthal RS; 600 N Wolfe St sted 560, Baltimore, MD, 21287, USA., Williams MS; Department of Medicine, Division of Cardiology, The Johns Hopkins University, 301 Mason Lord Drive, Suite 2400, Baltimore, MD, 21224, USA. mwillia1@jhmi.edu.

Publikováno v: Current atherosclerosis reports [Curr Atheroscler Rep] 2024 Nov; Vol. 26 (11), pp. 649-658. Date of Electronic Publication: 2024 Sep 07.

Purinergic inhibitory regulation of esophageal smooth muscle is mediated by P2Y receptors and ATP-dependent potassium channels in rats.

Autor: Shiina T; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan. shiina.takahiko.a0@f.gifu-u.ac.jp.; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan. shiina.takahiko.a0@f.gifu-u.ac.jp., Suzuki Y; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Horii K; Division of Biological Principles, Department of Physiology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Sawamura T; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Yuki N; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Horii Y; Institute for Glyco-Core Research (iGCORE), Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan., Shimizu Y; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.; Department of Basic Veterinary Science, Laboratory of Physiology, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.; Division of Animal Medical Science, Center for One Medicine Innovative Translational Research (COMIT), Gifu University Institute for Advanced Study, 1-1 Yanagido, Gifu, 501-1193, Japan.

Publikováno v: The journal of physiological sciences : JPS [J Physiol Sci] 2024 Apr 23; Vol. 74 (1), pp. 26. Date of Electronic Publication: 2024 Apr 23.

Modeling Platelet P2Y$_1$/$_{12}$ Pathway to Integrin Activation

Autor: Patel, Keshav B., Bergmeier, Wolfgang, Fogelson, Aaron L.

Through experimental studies, many details of the pathway of integrin $\alpha_{\rm IIb}\beta_3$ activation by ADP during the platelet aggregation process have been mapped out. ADP binds to two separate G protein coupled receptors on platelet surfaces

Externí odkaz: http://arxiv.org/abs/2410.13015

Efficacy and Safety of P2Y 12 monotherapy vs standard DAPT in patients undergoing percutaneous coronary intervention: meta-analysis of randomized trials.

Autor: Casula M; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Casu G; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Talanas G; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Spano A; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy., Tantry U; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Baltimore, MD, USA., Bilotta F; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Micheluzzi V; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Merella P; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Porcheddu T; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy; SIRIO MEDICINE Research Network, Sassari, Italy., Gorog DA; Cardiology Department, East and North Hertfordshire NHS Trust, Stevenage, UK; Faculty of Medicine, National Heart and Lung Institute, Imperial College, London, UK., Bonaca M; CPC Clinical Research, University of Colorado School of Medicine, USA., Jeong YH; CAU Thrombosis and Biomarker Center, Heart and Brain Hospital, Chung-Ang University, Gwangmyeong Hospital, Gwangmyeong, South Korea; Department of Internal Medicine, Chung-Ang University School of Medicine, Seoul, South Korea., Farkouh ME; Cedars Sinai Health System, Los Angeles, CA, USA., Kubica J; Department of Cardiology and Internal Medicine, Nicolaus Copernicus University, Bydgoszcz, Poland., Isgender M; Republican Clinical Hospital, Department of Cardiology, Azerbaijan Medical University, Department of Family Medicine, Baku, Azerbaijan., Gurbel PA; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Baltimore, MD, USA., Navarese EP; Clinical Experimental Cardiology, Clinical and Interventional Cardiology, University of Sassari, Sassari, Sardinia Island, Italy; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy; SIRIO MEDICINE Research Network, Sassari, Italy. Electronic address: epnavarese@uniss.it.

Publikováno v: Current problems in cardiology [Curr Probl Cardiol] 2024 Aug; Vol. 49 (8), pp. 102635. Date of Electronic Publication: 2024 May 13.

Timing of P2Y 12 Inhibitor Administration in Patients With STEMI Undergoing Primary PCI.

Autor: Almendro-Delia M; Acute Cardiovascular Care Unit, Hospital Universitario Virgen Macarena, Seville, Spain. Electronic address: trocor@gmail.com., Hernández-Meneses B; Acute Cardiovascular Care Unit, Hospital Universitario Virgen Macarena, Seville, Spain., Padilla-Rodríguez G; Acute Cardiovascular Care Unit, Hospital Universitario Virgen Macarena, Seville, Spain., Blanco-Ponce E; Cardiology Department. Hospital Universitari Arnau de Vilanova, Lleida, Spain., Arboleda-Sánchez JA; Intensive Care Unit, Hospital Regional Universitario de Málaga, Málaga, Spain., Rodríguez-Yáñez JC; Intensive Care Unit, Hospital de Puerto Real, Cádiz, Spain., Soto-Blanco JM; Intensive Care Unit, Hospital San Cecilio, Granada, Spain., Fernández-García I; Intensive Care Unit, Hospital Costa Del Sol, Málaga, Spain., Castillo-Caballero JM; Intensive Care Unit, Hospital Universitario Virgen de la Victoria, Malaga, Spain., García-Rubira JC; Acute Cardiovascular Care Unit, Hospital Universitario Virgen Macarena, Seville, Spain., Hidalgo-Urbano R; Acute Cardiovascular Care Unit, Hospital Universitario Virgen Macarena, Seville, Spain.

Publikováno v: Journal of the American College of Cardiology [J Am Coll Cardiol] 2024 Jun 25; Vol. 83 (25), pp. 2629-2639.