Zobrazeno 1 - 10
of 96
pro vyhledávání: '"P.W. Durbin"'
Publikováno v:
Radiation Protection Dosimetry. 79:433-443
Chelation therapy for internally deposited actinides has been shown to reduce acute radiation damage and chemical toxicity and the severity of late radiation effects. This review traces the development of chelating agents for the actinides from the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f803168adbe6abfc2117310066b99311
https://doi.org/10.1093/oxfordjournals.rpd.a032445
https://doi.org/10.1093/oxfordjournals.rpd.a032445
Autor:
R. Burgada, Kenneth N. Raymond, M.J. Pearce, J.C. Moody, I. Wilson, G.N. Stradling, P.W. Durbin, S.A. Gray
Publikováno v:
Radiation Protection Dosimetry. 53:319-322
The comparative efficacies of treatment with 3,4,3-LIHOPO and DTPA have been investigated in the rat after their subcutaneous and intramuscular injection. Commencement of treatment was delayed 30 min, 6 h or 1 d and the animals killed at 7 d. Under a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0856b399c18b84f6f987e93f7a718d2a
https://doi.org/10.1093/rpd/53.1-4.319
https://doi.org/10.1093/rpd/53.1-4.319
Publikováno v:
Radiation Protection Dosimetry. 53:305-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a13a9bd685b80b2ef84504c89b1cd8d
https://doi.org/10.1093/rpd/53.1-4.305
https://doi.org/10.1093/rpd/53.1-4.305
Autor:
T. Bailly, J. L. Poncy, Y. Leroux, R. Burgada, Roland Masse, François Paquet, P.W. Durbin, G. Rateau, Kenneth N. Raymond
Publikováno v:
Radiation Protection Dosimetry. 53:323-326
The ability of 3,4,3-LIHOPO, used at a dosage of 3 μmol.kg −1 of body weight, has been tested in Sprague-Dawley rats for reducing the retention of plutonium after inhalation of 238 Pu-TBP. The comparison was made with DTPA, the reference substance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dbe65eb263c9846c2a7e7979969e920
https://doi.org/10.1093/rpd/53.1-4.323
https://doi.org/10.1093/rpd/53.1-4.323
Autor:
Y. Leroux, J.C. Moody, S.A. Gray, G.N. Stradling, K.N. Raymond, P.W. Durbin, I. Wilson, R. Burgada, M.J. Pearce, T. Bailly
Publikováno v:
International Journal of Radiation Biology. 64:133-140
With DTPA as a comparison, the siderophore analogue 3,4,3-LIHOPO has been examined for its ability to remove 238Pu and 241Am from the rat after subcutaneous (s.c.) and intramuscular (i.m.) injection of about 200 Bq of each actinide (0.3 ng Pu, 1.6 ng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6767e3990865229f51b845209bd4788
https://doi.org/10.1080/09553009314551191
https://doi.org/10.1080/09553009314551191
Autor:
G.N. Stradling, S.A. Gray, M. Ellender, J.C. Moody, A. Hodgson, M. Pearce, I. Wilson, R. Burgada, T. Bailly, Y.G.P. Leroux, D. El Manouni, K.N. Raymond, P.W. Durbin
Publikováno v:
International Journal of Radiation Biology. 62:487-497
With DTPA as a comparison, the siderophore analogue code named 3,4,3-LIHOPO has been tested for its ability to remove 238Pu and 241Am from rats after their inhalation or intravenous injection as nitrate. The most effective treatment regimen for inhal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59454c4a58da98d1c8095426b56df6c
https://doi.org/10.1080/09553009214552381
https://doi.org/10.1080/09553009214552381
Autor:
G.N. Stradling, J.C. Moody, A. Hodgson, P.W. Durbin, S.A. Gray, S.J. Rodgers, P.N. Turowski, D.L. White, Kenneth N. Raymond
Publikováno v:
International Journal of Radiation Biology. 59:1269-1277
A hydroxypridinone derivative of desferrioxamine (Na-DFO-HOPO), a dihydroxamic derivative of diethylenetriaminepenta-acetic acid (ZnNa-DTPA-DX), and DTPA (CaNa3- and ZnNa3-DTPA) were tested at dosages of 30 mumol kg-1 for their ability to remove 238P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9edc8ec6a9fbb2ebf83629446386882
https://doi.org/10.1080/09553009114551131
https://doi.org/10.1080/09553009114551131
Autor:
T. Bailly, P.W. Durbin, R. Burgada, Jide Xu, M.-H. Hengé-Napoli, Kenneth N. Raymond, Birgitta Kullgren
Publikováno v:
Radiation protection dosimetry. 105(1-4)
Linear octadentate spermine based 3,4,3-LI(1,2-HOPO) and the mixed ligand, 3,4,3-LI(1,2-Me-3,2-HOPO), are the most effective agents for decorporation of Pu prepared so far; they are effective at low dosage, orally active, and of low toxicity at effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11647f7cc4cd0a2228a0d7b2ff288176
https://pubmed.ncbi.nlm.nih.gov/14527018
https://pubmed.ncbi.nlm.nih.gov/14527018
Autor:
M. J. Inskip, C. A. Franklin, C. L. Baccanale, William I. Manton, P.W. Durbin, Ellen J. O'Flaherty
Publikováno v:
Toxicology and applied pharmacology. 149(1)
Endogenous (predominantly bone) and exogenous lead were differentially labeled in two 11-year-old female cynomolgus monkeys (Macaca fascicularis) to establish the contributions of the two sources to blood lead. The monkeys had been administered a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784fa855d2be650c8b1ff4ffcdbeb888
https://pubmed.ncbi.nlm.nih.gov/9512721
https://pubmed.ncbi.nlm.nih.gov/9512721
Publikováno v:
Humanexperimental toxicology. 15(4)
Nine new octadentate ligands based on cyclic, spermine (3,4,3-LI), desferrioxamine (DFO), or H-shaped tetrakis amine (penten) molecular backbones were prepared containing catecholamide (CAM), carboxycatecholamide (CAM(C)), or terephthalamide (TAM) ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1370c20339764e08e8975e7c4a6c9c
https://pubmed.ncbi.nlm.nih.gov/8845226
https://pubmed.ncbi.nlm.nih.gov/8845226