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Autor:
Ritsuko Takahashi, I. Misra, Angela Geiger, Norio Tominaga, Masatoshi Sanjo, A. MaassenVanDenBrink, E.A.P. Steegers, S. Gupta, Hiroyuki Moriuchi, A. Benton, Abdullah Kumral, Kazim Tugyan, G. Morris, Zivanit Ergaz, Masato Tagawa, Ofra Peleg, Didem Cemile Yesilirmak, Rony Braunstein, Huseyin Baskin, P.R. Saxena, Akira Suzuki, Ilan Arad, Ozlem Giray, Olaf Dammann, S. Jyothi, Ann C. Rice, A. Valls-i-Soler, F.J. Alvarez-Díaz, Alfredo Cesario, Hiroo Chiba, Angela S. Geiger, Hasan Ozkan, A.G. Vulto, W. Visser, Steven M. Shapiro, Simge Aykan, Masaaki Yamada, A. Alvarez-Díaz, F. Goñi de Cerio, E. Hilario, Takeshi Ito, Nuray Duman, Masako Moriuchi, Masako Naganuma, Shingi Nakae, Bekir Ugur Ergur, S. Allen, Sermin Genc, Hidekazu Nishimura, L.M. Hanff, Osman Yilmaz, Kursad Genc, Manuel Hallen, D. Griffin, Sompong Sombati
Publikováno v:
Neonatology. 92:279-295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d63a7baf237ee60a824a50945db6d2
https://doi.org/10.1159/000107709
https://doi.org/10.1159/000107709
Autor:
P.R. Saxena, Kapil Kapoor, Christine Vayssettes-Courchay, J. P. C. Heiligers, Edwin W Willems, Tony Verbeuren, Antoinette MaassenVanDenBrink, Alex Cordi, Carlos M. Villalón
Publikováno v:
Cephalalgia. 24:425-438
Taking into account the drawbacks associated with the use of triptans, attempts are being made to explore other avenues for the treatment of migraine. Recently, it has been shown that both α1- and α2-adrenoceptors mediate the constriction of porcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3708e42acb0bcbfe0ace85d9811c10ac
https://doi.org/10.1111/j.1468-2982.2004.00684.x
https://doi.org/10.1111/j.1468-2982.2004.00684.x
Autor:
G. W. John, P. De Vries, J. P. C. Heiligers, Kapil Kapoor, P.R. Saxena, Beril Tom, Edwin W Willems
Publikováno v:
Cephalalgia, 22, 37-47. SAGE Publications Ltd
We investigated the effects of donitriptan, which possesses a uniquely high affinity and efficacy at 5-HT1B/1D receptors, on carotid and systemic haemodynamics in anaesthetized pigs. Donitriptan (0.16-100 μg kg-1, i.v.) dose-dependently decreased to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa56393bc1bf9e2d88019947960c81c3
https://pure.eur.nl/en/publications/c1a9f07a-bbf0-425d-873b-7584d9328b02
https://pure.eur.nl/en/publications/c1a9f07a-bbf0-425d-873b-7584d9328b02
Autor:
J. P. C. Heiligers, P.R. Saxena, Kapil Kapoor, Edwin W Willems, Carlos M. Villalón, P. De Vries, Beril Tom
Publikováno v:
Cephalalgia, 21, 110-119. SAGE Publications Ltd
It has recently been shown that the α-adrenoceptors mediating vasoconstriction of porcine carotid arteriovenous anastomoses resemble both α1- and α2-adrenoceptors, but no attempt was made to identify the specific subtypes (α1A, α1B and α1D) inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32838597504fcff993b8c5ad33738088
https://doi.org/10.1046/j.1468-2982.2001.00167.x
https://doi.org/10.1046/j.1468-2982.2001.00167.x
Publikováno v:
Cephalalgia, 20, 538-545. SAGE Publications Ltd
The mechanistically novel benzopyran derivative SB-220453, which is undergoing clinical evaluation in migraine, exhibits a high affinity for a selective, but not yet characterized, binding site in the human brain. It inhibits nitric oxide release and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e2ab979ca7317b87e0cdad38300f07
https://doi.org/10.1046/j.1468-2982.2000.00078.x
https://doi.org/10.1046/j.1468-2982.2000.00078.x
Publikováno v:
Naunyn-Schmiedebergs Archives of Pharmacology, 360, 591-596. Springer-Verlag
Ergot alkaloids, sumatriptan and the newer 5-HT1B/1D receptor agonists all contract cranial blood vessels and this effect seems to be primarily responsible for their efficacy in migraine. We have compared the contractile effects of a number of ergot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817881df7199fc0bb775468d9b6ee2c3
https://hdl.handle.net/1765/65067
https://hdl.handle.net/1765/65067
This volume contains the Proceedings of the invited lectures of the Second International Sym posium on SEROTONIN from Cell Biology to Pharmacology and Therapeutics held in Houston, Texas September 15-18, 1992. The meeting was held under the co-spon
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 358:212-219
It has been suggested that opening of cephalic arteriovenous anastomoses may be involved in the headache phase of migraine. Indeed, a number of acutely acting anti-migraine drugs, including the ergot alkaloids and sumatriptan, constrict porcine carot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff8b65b2ae7fbf3e8019c6da6ed2280
https://doi.org/10.1007/pl00005245
https://doi.org/10.1007/pl00005245