Zobrazeno 1 - 10
of 157
pro vyhledávání: '"P.N. Maton"'
Publikováno v:
Peptides. 11(6)
We have previously described that [Tyr 0 ]CGRP(28–37) acts as a receptor antagonist of rat CGRP in guinea pig pancreatic acini. We therefore examined other C-terminal peptides of CGRP for such activity. CGRP-acetyl(28–37) acetate did act as a rat
Publikováno v:
Gastroenterology. 99(4)
In 1983, all trials of omeprazole in humans were stopped because rats given the drug developed gastric endocrine cell hyperplasia and carcinoid tumors. Further studies in rats showed that drug-induced achlorhydria and hypergastrinemia caused these ch
Publikováno v:
Regulatory Peptides. 34:76
Autor:
P.N. Maton, H.J.F. Hodgson
Publikováno v:
Baillière's Clinical Gastroenterology. 1:35-61
In patients with hepatic metastases due to carcinoid tumours without systemic symptoms, surgery is indicated for readily resectable tumuors, in particular if the primary is also resectable. Such a policy should prolong life. If the tumuor is not read
Publikováno v:
Gastroenterology. 88:391-396
Normal volunteers (n = 6), patients with untreated celiac disease and subtotal villous atrophy (n = 6), patients with nonresponsive celiac disease (n = 2), and patients with celiac disease on a gluten-free diet with a virtually normal biopsy specimen
Publikováno v:
Regulatory Peptides. 8:9-19
To examine the distribution of cholecystokinins (CCKs) along the small intestine we examined the nature of CCKs in samples of jejunum, mid-intestine and ileum from human and porcine intestine. CCKs in intestinal mucosa were extracted by boiling in bo
Autor:
Aviva Petrie, Vs Chadwick, E. A. Fagan, Humphrey Hodgson, Mark B. Pepys, Roland Dyck, P.N. Maton
Publikováno v:
European Journal of Clinical Investigation. 12:351-359
Prospective measurements were made of serum C-reactive protein levels and erythrocyte sedimentation rate in sixty-four patients with Crohn's disease and fifty with ulcerative colitis. The results were related to clinical assessment of disease activit
Publikováno v:
European Journal of Clinical Investigation. 12:97-105
The effects of intraluminal sodium taurocholate (STC) on biliary and pancreatic secretion were studied in man using a duodenal perfusion technique and indocyanine green (ICG) as an exogenous biliary marker. Duodenal perfusion with 15 or 30 mmol/l STC
Publikováno v:
Clinical Science. 69:259-263
1. To determine the functional significance of physiological plasma concentrations of cholecystokinin, five volunteers each received graded doses of intravenous infusions of cholecystokinin octapeptide (CCK-8). At each dose plasma concentrations of C
Autor:
J A Cherner, M.J. Collen, Robert T. Jensen, Jerry D. Gardner, P.N. Maton, K.E. McArthur, J. M. Howard
Publikováno v:
Digestion. 32:59-61
The safety and efficacy of the new, highly potent histamine H2 receptor antagonist, famotidine, was evaluated in nine patients with Zollinger-Ellison syndrome. Famotidine was found to be sa