Výsledky vyhledávání - "P.M.J. Burgers"

The application of levulinic acid as protective group to the synthesis of tetradecaribonucleotide U-A-U-A-U-A-U-A-U-A-U-A-U-A via the modified phosphotriester method

Autor: J. H. Van Boom, P.M.J. Burgers

Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 97:73-80

Acylation on the 5i-position of 2i-O-methoxytetrahydropyranyl ribonucleosides la (B=U) and 2a (B=Aan) with levulinic acid, followed by phosphorylation of the 3i-hydroxy function with the monofunctional phosphorylating agent 2,2,2-trichloroethyl 2-chl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c799dea039d682ae85ab26711e4a38a
https://doi.org/10.1002/recl.19780970305

Zobrazit plný text záznamu

The preparation of diribonucleoside monophosphates containing 4-thiouridine via the phosphotriester approach

Autor: J. H. Van Boom, P.M.J. Burgers, J. A. J. Den Hartog, G. A. Van Der Marel

Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 95:108-112

A new procedure for the synthesis of 2′-ketals of 4-thiouridine (1c), N4-methylcytidine (2a) and N4,N4-dimethylcytidine (2b), starting from the. easily accessible 3′,5′-di-O-acetyl-2′-O-(methoxytetrahydropyranyl)uridine (1b), has been devised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84b964ca81913daf47b6b331868d7da2
https://doi.org/10.1002/recl.19760950507

Zobrazit plný text záznamu

Recueil des Travaux Chimiques des Pays-Bas Journal of the Royal Netherlands Chemical Society: General method for the synthesis of 3′,5′-diesters and 2′-acetals of the four common nucleosides

Autor: C. A. G. Haasnoot, P.M.J. Burgers, J. H. Van Boom, Colin B. Reese

Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 96:91-95

A procedure suitable for the preparation on a large scale of 5′-O-(methoxyacetyl)-3′-O-propionylribonucleosides (9a-d) from each of the four main ribonucleosides 6a-d has been developed. The usefulness of 9a-d as starting products for the synthes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::256d37aaf95b1eac86374e0428bf7922
https://doi.org/10.1002/recl.19770960402

Zobrazit plný text záznamu

Eukaryotic DNA Polymerase δ

Autor: P.M.J. Burgers

DNA polymerase δ (Pol δ) is the DNA synthetic workhorse in the eukaryotic cell. Besides its essential function on the lagging strand of the DNA replication fork, this enzyme also functions during DNA recombinational processes, various DNA repair pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d36bdf6aabd76105c74343ad24e5a2e
https://doi.org/10.1016/b978-0-12-378630-2.00305-4

Zobrazit plný text záznamu

Formation of 5′-amino-deoxy-dinucleoside monophosphates in the de-blocking of oligonucleotides via intermediate aryl phosphotriesters

Autor: J.F.M. de Rooij, P.M.J. Burgers, G. Wille-Hazeleger, J. H. Van Boom

Publikováno v: Nucleic Acids Research. 5:s37-s42

Ammonolysis of aryl groups from internucleotide linkages of oligonucleotides with a free 5′-hydroxy function leads to the formation of a considerable amount of side-products.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5ffa0ab22637787d6dda8ca0fbec0c
https://doi.org/10.1093/nar/1.suppl_1.s37

Zobrazit plný text záznamu

Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16s ribosomal rna of escherichia coli: preparation op U-C-C-U-U-A and A-C-C-U-C-C-U-U-A via the modified phosphotriester method

Autor: P.M.J. Burgers, J. H. Van Boom, C. H. M. Verdegaal, G. Wille

Publikováno v: Tetrahedron. 34:1999-2007

The synthesis of oligoribonucleotides U-C-C-U-U-A and A-C-C-U-C-C-U-U-A, which are located at the 3'-terminus of 16S rRNA of E. coli , is described. The key-intermediates in the synthesis of these compounds are the fully-protected mononucleotides 5a-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00aefca35c003adc2e7d97ee4c41a9b1
https://doi.org/10.1016/0040-4020(78)80109-4

Zobrazit plný text záznamu

Synthesis of oltgonucleotides with sequences identical with or analogous to the 3′-end of 16S ribosomal RNA of Es cherichia coli: preparation of m62A-C-C-U-C-C and A-C-C-U-C-m42C via phosphotriester intermediates1

Autor: R. Crea, G. Wille, G. A. Van Der Marel, P.M.J. Burgers, J. H. Van Boom

Publikováno v: Nucleic Acids Research. 4:747-759

The synthesis of two fully-protected hexanucleotides (11a and 11b) via a phosphotriester approach, which is based on the use of two types of protecting groups for the internucleotide linkages, i.e. one 2,2,2-tribromo-ethyl at the 5'-terminus and four

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c389d0a8501676c9908cd84aba7dc4fe
https://doi.org/10.1093/nar/4.3.747

Zobrazit plný text záznamu

Synthesis of oligonucleotides with sequences identical with or analogous to the 3′ - end of I6S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method1

Autor: J. H. Van Boom, G. A. Van Der Marel, P.M.J. Burgers, C. H. M. Verdegaal, G. Wille

Publikováno v: Nucleic Acids Research. 4:1047-1063

A combination of two different methods for the synthesis of oligoribonucleotides, i.e. the two-step phosphotriester method with 2-chlorophenyl phosphate as bifunctional phosphate source and the modified triester method with 2,2,2-trichloroethyl 2-chl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f09887525bf0c4b9316b27b64ab0585f
https://doi.org/10.1093/nar/4.4.1047

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání