Výsledky vyhledávání - "P.K.R. Kumar"

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Influence of medium- and long-range interactions in different folding types of globular proteins

Autor: K Gayatri, Thirumananseri Kumarevel, Samuel Selvaraj, M. Michael Gromiha, P.K.R Kumar

Publikováno v: Biophysical Chemistry. 99:189-198

Recognition of protein fold from amino acid sequence is a challenging task. The structure and stability of proteins from different fold are mainly dictated by inter-residue interactions. In our earlier work, we have successfully used the medium- and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc07a1087b036a94b9a3779fb7befdf
https://doi.org/10.1016/s0301-4622(02)00183-7

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Chemical probing studies of variants of the genomic hepatitis delta virus ribozyme by primer extension analysis

Autor: P.K.R. Kumar, Kazunari Taira, Satoshi Nishikawa

Publikováno v: Scopus-Elsevier

We have investigated in detail the higher order structure of the genomic hepatitis delta virus (HDV) ribozyme using various base-specific chemical probes under native, semi-denaturing, and denaturing conditions. The bases of the HDV ribozyme were pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e808e2028c35024bc9f1240857a8000a
https://doi.org/10.1021/bi00168a025

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Akademický článek

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Plasmid instabilities of single and three-plasmid systems in Escherichia coli during continuous cultivation

Autor: R. Geiger, H.-E. Maschke, P.K.R. Kumar, Karl Schügerl

Publikováno v: Journal of Biotechnology. 24:235-251

Plasmid instabilities in E. coli JM103 carrying three plasmids (pRK248cI, pMTC48, pEcoR4) and a single plasmid system (pTG206) for the production of fusion EcoRI (SPA::EcoRI) and catechol 2,3-dioxygenase, respectively, were investigated in continuous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dcc2249d9659d982397cea3f41f321
https://doi.org/10.1016/0168-1656(92)90034-7

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Random mutations to evaluate the role of bases at two important single-stranded regions of genomic HDV ribozyme

Autor: Kazunari Taira, Fumiko Nishikawa, Junji Kawakami, P.K.R. Kumar, Hirotsugu Miyashiro, Young-Ah Suh, Satoshi Nishikawa

Publikováno v: Nucleic Acids Research. 20:3919-3924

In elucidating function of two important single-stranded regions [SSrA (726-731 nt) and SSrB (762-766 nt)] derived mainly from three secondary structure models in genomic hepatitis delta virus (HDV) ribozyme possessing self-cleavage activity, we have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40d089dd8cee7925b3f6fd52abf82e5
https://doi.org/10.1093/nar/20.15.3919

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Supercritical fluid extraction from dry mouldy bran for the purification of gibberellic acid from the concomitant products produced during solid state fermentation

Autor: P.K.R. Kumar, K. Udaya Sankar, B.K. Lonsane

Publikováno v: The Chemical Engineering Journal. 46:B53-B58

Dry mouldy bran (DMB) containing gibberellic acid (GA3) is a solid fermented material resulting from solid state fermentation by Gibberella fujikuroi P-3. Samples of this bran were subjected to supercritical fluid extraction (SCFE) to remove other co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e9c4b3c2b757ab5d94cf43facef1eca
https://doi.org/10.1016/0300-9467(91)80030-z

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In vitro selection of RNA aptamers against cellular and abnormal isoform of mouse prion protein

Autor: Takashi Yokoyama, Ken Noda, P.K.R. Kumar, Fumiko Nishikawa, Satoru Sekiya, Satoshi Nishikawa

Publikováno v: Scopus-Elsevier

Prion disease is caused by conformational change of normal cellular type of prion protein (PrP(c)) folding into abnormal type (PrP(sc)). We succeeded to isolate anti-PrP(c) aptamers. In the presence of competitor RNA, anti-PrP(c) aptamers showed high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ddd82c52548a622aef9b05290ddb86
https://pubmed.ncbi.nlm.nih.gov/17150783

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Structure in the local environment of Zn2+ion in the anti-termination protein ofBacillus subtilis

Autor: Hiroshi Mizuno, P. Fons, P.K.R. Kumar, D. Balasundaresan

Publikováno v: Acta Crystallographica Section A Foundations of Crystallography. 64:C110-C111

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d409d248f80e31a8b9cff865edbf4551
https://doi.org/10.1107/s0108767308096463

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Artificial evolution and natural ribozymes

Autor: P.K.R. Kumar, Andrew D. Ellington

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 9(12)

In vitro selection techniques have been used to probe the sequence, structure, and function of natural ribozymes such as the viroid hammerheads and group I self-splicing introns. These artificial evolution experiments help to delimit the range of alt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc1ece5a383d750306cb6ea2cc77f87
https://pubmed.ncbi.nlm.nih.gov/7672511

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