Zobrazeno 1 - 10 of 89 pro vyhledávání: '"P.K. Eagon"'
1
Hepatic hyperplasia and cancer in rats: alterations in copper metabolism
Autor: Kalipatnapu N. Rao, Annette G. Teepe, Stasa D. Tadic, Bonnie E. Beiler, Marilyn J. Epley, Mary S. Elm, P.K. Eagon, Hisashi Shinozuka
Publikováno v: Carcinogenesis. 20:1091-1096
We previously demonstrated that rats exposed to the peroxisome proliferator (PP) diethylhexylphthalate (DEHP) had reduced serum ceruloplasmin (CP) oxidase activity, which suggests tissue copper deposition. Copper is highly toxic in excess, and result
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417da87c94d62155b9155a7698e2ea03
https://doi.org/10.1093/carcin/20.6.1091
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2
Sex steroid metabolism and receptor status in hepatic hyperplasia and cancer in rats
Autor: P.K. Eagon, Krishna Rao, MJ Epley, H Shinozuka, Elm
Publikováno v: Gastroenterology. 110:1199-1207
BACKGROUND & AIMS: Both androgenic and estrogenic steroids have been implicated in the development and course of several liver diseases, including hepatocellular carcinoma. The aim of this study was to investigate temporal changes in hepatic estrogen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4e7ca9049e4500ef937bedc0224efd
https://doi.org/10.1053/gast.1996.v110.pm8613010
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3
DI(2-ethylhexyl)phthalate-induced changes in liver estrogen metabolism and hyperplasia
Autor: Edward P. Brady, P.K. Eagon, Nalini Chandar, Mary S. Elm, Kalipatnapu N. Rao, Marilyn J. Epley
Publikováno v: International Journal of Cancer. 58:736-743
Exposure to a common phthalate, di(2-ethylhexyl)phthalate (DEHP), is associated with liver hyperplasia prior to the development of hepatocellular carcinoma in rodents. The exact mechanism of liver hyperplasia as well as tumorigenesis by this agent is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180baedec3a9530b785c737ffb73c170
https://doi.org/10.1002/ijc.2910580519
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4
Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury
Autor: Mary S. Elm, David C. Whitcomb, Stasa D. Tadic, Vladimir M. Subbotin, Gijsberta J. Van Londen, P.K. Eagon, Ha-Sheng Li
Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 93(3)
Sex differences in susceptibility to alcohol-induced liver injury have been observed in both humans and experimental animal models. Using a standard model of alcohol-induced fatty liver injury and microarray analysis, we have identified differential
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8bfa2cfb55690e208e11f551d77eb0
https://pubmed.ncbi.nlm.nih.gov/12183503
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10
Effect of chronic ethanol ingestion on alpha-mannosidase isoenzymes in rat liver
Autor: P.K. Eagon, P. Lauro, Robert H. Glew, P.S. Lechner, A. A. Okolo
Publikováno v: Clinica chimica acta; international journal of clinical chemistry. 174(3)
Identification of biochemical changes induced by ethanol ingestion would aid in the diagnosis and management of many alcohol-related problems in man. In this paper we identify a pH 5.5 alpha-mannosidase activity in the rat which is affected by chroni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0071bfa5676b99c01f47ad9a5fb76011
https://pubmed.ncbi.nlm.nih.gov/3390956
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