Zobrazeno 1 - 10
of 141
pro vyhledávání: '"P.J.G. Butler"'
Autor:
Mariann Bienz, Yoshiki Higuchi, Thomas Schwarz-Romond, Naoki Shibata, P.J.G. Butler, Akira Kikuchi, Marc Fiedler
Publikováno v:
Nature Structural & Molecular Biology. 14:484-492
The Wnt signaling pathway controls numerous cell fates in animal development and is also a major cancer pathway. Dishevelled (Dvl) transduces the Wnt signal by interacting with the cytoplasmic Axin complex. Dvl and Axin each contain a DIX domain whos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829010ccfff0e61ca42dad0669f60c6f
https://doi.org/10.1038/nsmb1247
https://doi.org/10.1038/nsmb1247
Autor:
L.E. Kemp, S Pillozzi, P.J.G. Butler, Ermanno Gherardi, Oliver Holmes, F Carafoli, Malcolm Lyon, Jon A. Deakin
Publikováno v:
Journal of Molecular Biology. 367:395-408
Hepatocyte growth factor/scatter factor (HGF/SF), the ligand for the receptor tyrosine kinase encoded by the c-Met proto-oncogene, is a multidomain protein structurally related to the pro-enzyme plasminogen and with major roles in development, tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdf960e56e0fffc9e78116c7960c4b2
https://doi.org/10.1016/j.jmb.2006.12.061
https://doi.org/10.1016/j.jmb.2006.12.061
Publikováno v:
Journal of Molecular Biology. 340:797-808
EmrE is a multidrug transporter that utilises the proton gradient across bacterial cell membranes to pump hydrophobic cationic toxins out of the cell. The structure of EmrE is very unusual, because it is an asymmetric homodimer containing eight alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19faff245994f12603815a3cefcf56c9
https://doi.org/10.1016/j.jmb.2004.05.014
https://doi.org/10.1016/j.jmb.2004.05.014
Autor:
James A. Huntington, Murray Stewart, C. Chaillan-Huntington, Carl M. Feldherr, Debra Akin, P.J.G. Butler
Publikováno v:
Journal of Molecular Biology. 314:465-477
Nuclear transport factor 2 (NTF2) mediates nuclear import of RanGDP, a central component of many nuclear trafficking pathways. NTF2 is a homodimer and each chain has independent binding sites for RanGDP and nuclear pore proteins (nucleoporins) that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7784997249333e343d89b92bd385bf87
https://doi.org/10.1006/jmbi.2001.5136
https://doi.org/10.1006/jmbi.2001.5136
Publikováno v:
Journal of Molecular Biology. 290:331-345
The yeast non-Mendelian factor [URE3] propagates by a prion-like mechanism, involving aggregation of the chromosomally encoded protein Ure2. The [URE3] phenotype is equivalent to loss of function of Ure2, a protein involved in regulation of nitrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b17e78f3b82fbd911169633cc5fc92
https://doi.org/10.1006/jmbi.1999.2872
https://doi.org/10.1006/jmbi.1999.2872
Autor:
P.J.G. Butler
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 354:537-550
The tobacco mosaic virus (TMV) particle was the first macromolecular structure to be shown to self–assemble in vitro , allowing detailed studies of the mechanism. Nucleation of TMV self–assembly is by the binding of a specific stem–loop of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a650cf4089761859b9d9b60c584f41de
https://doi.org/10.1098/rstb.1999.0405
https://doi.org/10.1098/rstb.1999.0405
Publikováno v:
Journal of Molecular Biology. 265:590-602
The major intrinsic protein (MIP) from bovine lens fibre membranes has been purified from unstripped membranes using a single ion-exchange chromatography step (MonoS) in the non-ionic detergent octyl-beta-D-glucopyranoside (OG). SDS-PAGE has confirme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8ed027ddc2c6a79ab86c0d109fdc72
https://doi.org/10.1006/jmbi.1996.0763
https://doi.org/10.1006/jmbi.1996.0763
Publikováno v:
Proceedings of the National Academy of Sciences. 92:6509-6513
Many transcription factors and some other proteins contain glutamine repeats; their abnormal expansion has been linked to several dominantly inherited neuro-degenerative diseases. Having found that poly(L-glutamine) alone forms beta-strands held toge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9cacbefd5daa4cc443f43210dd0a7c
https://doi.org/10.1073/pnas.92.14.6509
https://doi.org/10.1073/pnas.92.14.6509
Publikováno v:
Journal of Molecular Biology. 224:381-394
We have employed the rapid-freeze technique to prepare specimens for electron microscopy of a coat protein solution of tobacco mosaic virus at equilibrium at pH 7·0 and 6·8, ionic strength 0·1 m and 20 °C. The former are the conditions for the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f76ec3a4b48a23c75927e3c22d4b5a9
https://doi.org/10.1016/0022-2836(92)91002-7
https://doi.org/10.1016/0022-2836(92)91002-7
Autor:
Tom L. Blundell, Julian Gough, Ermanno Gherardi, Ricardo Núñez Miguel, G. Hartmann, A. Bandyopadhyay, Mark Youles, L. Iamele, P.J.G. Butler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(21)
Little is known about the large ectodomain of MET, the product of the c- met protooncogene and receptor for hepatocyte growth factor/scatter factor (HGF/SF). Here, we establish by deletion mutagenesis that the HGF/SF and heparin-binding sites of MET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaa085101f8d485adaeef1d123a55db
https://pubmed.ncbi.nlm.nih.gov/14528000
https://pubmed.ncbi.nlm.nih.gov/14528000