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Contribution of planar (0-1 ortho) and nonplanar (2-4 ortho) fractions of aroclor 1260 to the induction of altered hepatic foci in female Sprague-Dawley rats

Autor: S. Jensen, Jan H. Koeman, A. Brouwer, H. van den Berg, H. Sundberg, Gunilla Scheu, P.G. Wester, Åke Bergman, J. L. de Boer, S.A. van der Plas

Publikováno v: Toxicology and Applied Pharmacology, 169, 255-268
van der Plas, S A, Sundberg, H, van den Berg, H, Scheu, G, Wester, P, Jensen, S, Bergman, A, de Boer, J, Koeman, J H & Brouwer, A 2000, ' Contribution of planar (0-1 ortho) and nonplanar (2-4 ortho) fractions of aroclor 1260 to the induction of altered hepatic foci in female Sprague-Dawley rats ', Toxicology and Applied Pharmacology, vol. 169, no. 3, pp. 255-268 . https://doi.org/10.1006/taap.2000.9058
Toxicology and Applied Pharmacology 169 (2000)
Toxicology and Applied Pharmacology, 169(3), 255-268. Academic Press Inc.

The hepatic tumor promoting activity of the planar 0-1 ortho ( approximately 9.7% w/w) and the nonplanar 2-4 ortho ( approximately 90.3% w/w) fraction of the commercial PCB mixture Aroclor 1260 was studied using a medium-term two-stage initiation/pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8790dbbf9a575440a4835839db3c1422
https://research.vu.nl/en/publications/e0a2d500-b693-4c91-bb55-7cd05fb75505

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Toxaphene: a challenging analytical problem

Autor: J. de Boer, U.A.Th. Brinkman, A. Schelvis, P.G. Wester, H.-J. De Geus

Publikováno v: Journal of Environmental Monitoring, 2(5), 503-511
Journal of Environmental Monitoring 2 (2000) 5
Journal of Environmental Monitoring, 2(5), 503-511. Royal Society of Chemistry
de Geus, H J, Wester, P G, Schelvis, A, de Boer, J & Brinkman, U A T 2000, ' Toxaphene: a challenging analytical problem ', Journal of Environmental Monitoring, vol. 2, no. 5, pp. 503-511 . https://doi.org/10.1039/b002867n

The analysis of toxaphene, a highly complex mixture of chlorinated bornanes, bornenes and camphenes, is a challenging problem, especially as individual congeners are present at trace levels in biota and other relevant samples. The complicated nomencl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda232d8b1311c2fc15fe6ecd3b51538
https://research.vu.nl/en/publications/34231068-c203-4ae0-a584-4ecd0bd11842

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The use of a microsomal in vitro assay to study phase I biotransformation of chlorobornanes (toxaphene®) in marine mammals and birds

Autor: Jan P. Boon, M.S. Helle, H.J.C. Klamer, E. Roex, B. Govers, P.G. Wester, J. de Boer, M.T.J. Hillebrand, D. Pastor, H.M. Sleiderink, M. Dekker, D. Morse, A. van Schanke

Publikováno v: Comparative Biochemistry and Physiology. C, Pharmacology, Toxicology and Endocrinology 121 (1998)
Comparative Biochemistry and Physiology. C, Pharmacology, Toxicology and Endocrinology, 121, 385-403

The factors determining the bioaccumulation of lipophilic compounds in wildlife are often poorly understood, partly because it is difficult to do in vivo experiments with animals such as marine mammals and birds. To evaluate the role of phase I biotr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adabfed43fa0494ce6d3be07f0a5c35
https://doi.org/10.1016/s0742-8413(98)10058-0

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Determination of tris(4-chlorophenyl) methanol and tris(4-chlorophenyl) methane in fish, marine mammals and sediment

Autor: P.G. Wester, E.H.G. Evers, U.A.T. Brinkman, J. de Boer

Publikováno v: Environmental Pollution, 93(1), 39-47. Elsevier Limited
Environmental Pollution, 93(1), 39-47
de Boer, J, Wester, P G, Evers, E H G & Brinkman, U A T 1996, ' Determination of tris(4-chlorophenyl)methanol and tris(4-chlorophenyl)methane in fish, marine mammals and sediment. ', Environmental Pollution, vol. 93, no. 1, pp. 39-47 . https://doi.org/10.1016/0269-7491(96)00017-6
Environmental Pollution 93 (1996) 1

Tris (4-chlorophenyl)methanol (TCP) and tris (4-chlorophenyl)methane (TCPMe) were determined in aquatic organisms and sediment by a method based on Soxhlet extraction, gel permeation chromatography, fractionation over silica and gas chromatography/ma

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https://doi.org/10.1016/0269-7491(96)00017-6

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Determination of toxaphene in human milk from Nicaragua and in fish and marine mammals from the northeastern Atlantic and the North Sea

Autor: Jacob de Boer, P.G. Wester

Publikováno v: Chemosphere. 27:1879-1890

Concentrations of toxaphene (polychlorinated monoterpenes, chlorobornanes) were determined in human milk samples from Nicaragua and in fish from the North Sea. Relatively high toxaphene levels were found in the Nicaraguan human milk samples. The lack

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https://doi.org/10.1016/0045-6535(93)90384-h

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Method for the analysis of non-ortho substituted chlorobiphenyls in fish and marine mammals

Autor: J. de Boer, F. van der Valk, C.J.N. Stronck, M.J.M. Daudt, P.G. Wester

Publikováno v: Chemosphere. 25:1277-1283

A method has been developed for the analysis of non-ortho substituted chlorobiphenyls (CBs) in fish. The method consists of a saponification, clean-up over alumina and silica and HPLC fractionation over porous graphitic carbon. GC/NCI-MS is used for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2408f62734983d591776c046953f2533
https://doi.org/10.1016/0045-6535(92)90142-e

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Chlorobiphenyls and organochlorine pesticides in various sub-Antarctic organisms

Autor: P.G. Wester, Jacob de Boer

Publikováno v: Marine Pollution Bulletin. 22:441-447

Brains, livers and muscles of two Gentoo penguins ( Pygoscelis papua ) from the Falkland Islands and muscles of Argentinian hake ( Merluccius merluccius hubbsi ), flying fish ( Cypselurus cyanopterus ) and squid ( Illex illecebroscus argentinus ) wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7a6280ed1077bd5e109f7267f5d1691
https://doi.org/10.1016/0025-326x(91)90212-b

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Determination of toxaphene in fish from Northern Europe

Autor: P.G. Wester, Frank van der Valk

Publikováno v: Chemosphere. 22:57-66

Concentrations of toxaphene were determined in fish from the Netherlands and adjacent marine areas by GC/NCl-MS after thorough clean-up. Levels of toxaphene lay between 0.1 and 7 mg / kg on lipid basis. Toxaphene components showing different environm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71b809c854705cd718ee8138030a36b4
https://doi.org/10.1016/0045-6535(91)90264-e

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Enantiomer fractions instead of enantiomer ratios

Autor: P.G. Wester, Jacob de Boer, Udo A. Th. Brinkman, Henk-Jan de Geus

Publikováno v: Chemosphere, 41(5), 725-727
Chemosphere 41 (2000) 5
Chemosphere, 41(5), 725-727. Elsevier Limited
de Geus, H J, Wester, P G, de Boer, J & Brinkman, U A T 2000, ' Enantiomer fractions instead of enantiomer ratios ', Chemosphere, vol. 41, no. 5, pp. 725-727 . https://doi.org/10.1016/S0045-6535(99)00431-2

The use of enantiomer ratios (ERs) to indicate the relative amounts of a pair of enantiomers in a sample has some disadvantages. Enantiomer fractions (EFs) are proposed as all alternative expression to eliminate the difficulties. (C) 2000 Elsevier Sc

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https://research.wur.nl/en/publications/enantiomer-fractions-instead-of-enantiomer-ratios

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